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Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing.
Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins.
Enhanced Cas12a editing in mammalian cells and zebrafish.
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins.
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.
Genome-wide detection and analysis of CRISPR-Cas off-targets.
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag.
CRISPR Cas Systems