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Amyloid Precursor Protein Secretases
Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease.
Identification of beta-secretase (BACE1) substrates using quantitative proteomics.
Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor.
Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
Serum Amyloid A Protein