This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to
Kaufman, Michael
| Item Type | Name |
|
Concept
|
Protein Kinase Inhibitors
|
|
Academic Article
|
Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036.
|
|
Academic Article
|
Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants.
|
|
Academic Article
|
Discovery of vimseltinib (DCC-3014), a highly selective CSF1R switch-control kinase inhibitor, in clinical development for the treatment of Tenosynovial Giant Cell Tumor (TGCT).
|
|
Academic Article
|
Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase.
|
|
Academic Article
|
Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
|
|
Academic Article
|
Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region.
|
|
Academic Article
|
Vimseltinib: A Precision CSF1R Therapy for Tenosynovial Giant Cell Tumors and Diseases Promoted by Macrophages.
|
|
Academic Article
|
Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.
|
|
Academic Article
|
Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors.
|
- Protein Kinase Inhibitors