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Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients.
Huntington's disease: silencing a brutal killer.
Polymorphism, Single Nucleotide
Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells.
Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities.
Polymorphism Single Nucleotide