Sign in to edit your profile (add interests, mentoring, photo, etc.)
    Keywords
    Last Name
    Institution

    Lloyd Hutchinson PhD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentPathology
    AddressUniversity of Massachusetts Medical School
    One Innovation Drive, Biotech Three
    Worcester MA 01605
    Phone508-793-6240
        Overview 
        Narrative

        Academic Background:

        BS -1987, Microbiology and Chemistry, Univ. of Guelph, Guelph ON Canada

        PhD.- 1996, Molecular Virology and Immunology, McMaster Univ., Hamilton ON Canada

        Postdoctoral Fellow -2004, Molecular Oncology, Vascular Biology Program, Children’s Hospital, Harvard Medical School, Boston MA

        Research Interests :Dr. Hutchinson's picture

        My research encompasses tumor biology including hematopathology and solid tumors. A primary focus is the discovery and development of novel technology and cancer biomarkers for early cancer detection. The eventual goal is to provide oncologists with tools that enable early intervention and better outcomes for patients. Diagnostic assays and biomarkers in development may be used for early detection, to assist in diagnosis, prognosis, and treatment decisions or to monitor levels of minimal residual disease



        Bibliographic 
        selected publications
        List All   |   Timeline
        1. Wang SA, Hutchinson L, Tang G, Chen SS, Miron PM, Huh YO, Jones DM, Bueso-Ramos C, Verstovsek S, Medeiros LJ, Miranda RN. Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: Clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components. Am J Hematol. 2013 Mar; 88(3):219-24.
          View in: PubMed
        2. Menon MP, Hutchinson L, Garver J, Jaffe ES, Woda BA. Transformation of follicular lymphoma to epstein-barr virus-related hodgkin-like lymphoma. J Clin Oncol. 2013 Feb 10; 31(5):e53-6.
          View in: PubMed
        3. Cerny J, Yu H, Ramanathan M, Raffel GD, Walsh WV, Fortier N, Shanahan L, O'Rourke E, Bednarik J, Barton B, Kroll-Desrosiers A, Hao S, Woda B, Hutchinson L, M Evens A, Rosmarin AG, Nath R. Expression of CD25 independently predicts early treatment failure of acute myeloid leukaemia (AML). Br J Haematol. 2012 Nov 1.
          View in: PubMed
        4. Zhang H, Peng C, Hu Y, Li H, Sheng Z, Chen Y, Sullivan C, Cerny J, Hutchinson L, Higgins A, Miron P, Zhang X, Brehm MA, Li D, Green MR, Li S. The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. Nat Genet. 2012 Jul 15.
          View in: PubMed
        5. Piperdi B, Walsh WV, Bradley K, Zhou Z, Bathini V, Hanrahan-Boshes M, Hutchinson L, Perez-Soler R. Phase-I/II Study of Bortezomib in Combination with Carboplatin and Bevacizumab as First-Line Therapy in Patients With Advanced Non-Small-Cell Lung Cancer. J Thorac Oncol. 2012 Jun; 7(6):1032-40.
          View in: PubMed
        6. Hure MC, Elco CP, Ward D, Hutchinson L, Meng X, Dorfman DM, Yu H. Histiocytic sarcoma arising from clonally related mantle cell lymphoma. J Clin Oncol. 2012 Feb 10; 30(5):e49-53.
          View in: PubMed
        7. Kurian EM, Caporelli ML, Baker S, Woda B, Cosar EF, Hutchinson L. Cervista HR and HPV 16/18 assays vs hybrid capture 2 assay: outcome comparison in women with negative cervical cytology. Am J Clin Pathol. 2011 Nov; 136(5):808-16.
          View in: PubMed
        8. Dvorak K, Goldman A, Kong J, Lynch JP, Hutchinson L, Houghton JM, Chen H, Chen X, Krishnadath KK, Westra WM. Molecular mechanisms of Barrett's esophagus and adenocarcinoma. Ann N Y Acad Sci. 2011 Sep; 1232:381-91.
          View in: PubMed
        9. Shi M, Minehart Miron P, Hutchinson L, Woda BA, Nath R, Cerny J, Yu H. Anaplastic lymphoma kinase-positive large B-cell lymphoma with complex karyotype and novel ALK gene rearrangements. Hum Pathol. 2011 Oct; 42(10):1562-7.
          View in: PubMed
        10. Hutchinson L, Stenstrom B, Chen D, Piperdi B, Levey S, Lyle S, Wang TC, Houghton J. Human Barrett's Adenocarcinoma of the Esophagus, Associated Myofibroblasts, and Endothelium Can Arise from Bone Marrow-Derived Cells After Allogeneic Stem Cell Transplant. Stem Cells Dev. 2011 Jan; 20(1):11-7.
          View in: PubMed
        11. Cerny J, Wang S, Miron P, Hutchinson L, Brettler D. EBV-negative Hodgkin lymphoma in ZAP-70-positive B-cell lymphocytic leukemia patient. Ann Hematol. 2009 May; 88(5):495-7.
          View in: PubMed
        12. Cerny J, Fadare O, Hutchinson L, Wang SA. Clinicopathological features of extramedullary recurrence/relapse of multiple myeloma. Eur J Haematol. 2008 Jul; 81(1):65-9.
          View in: PubMed
        13. Pozdnyakova O, Stachurski D, Hutchinson L, Ramakrishnan S, Miron PM. Trisomy 8 in B-cell chronic lymphocytic leukemia. Cancer Genet Cytogenet. 2008 May; 183(1):49-52.
          View in: PubMed
        14. Wang SA, Yue G, Hutchinson L, Landry ML, Hasserjian RP, Hao S, Galili N, Raza A, Woda BA. Myelodysplastic syndrome with pure red cell aplasia shows characteristic clinicopathological features and clonal T-cell expansion. Br J Haematol. 2007 Jul; 138(2):271-5.
          View in: PubMed
        15. Stachurski D, Miron PM, Al-Homsi S, Hutchinson L, Harris NL, Woda B, Wang SA. Anaplastic lymphoma kinase-positive diffuse large B-cell lymphoma with a complex karyotype and cryptic 3' ALK gene insertion to chromosome 4 q22-24. Hum Pathol. 2007 Jun; 38(6):940-5.
          View in: PubMed
        For assistance with using Profiles, please refer to the online tutorials or contact UMMS Help Desk or call 508-856-8643.
        Lloyd's Networks
        Click the "See All" links for more information and interactive visualizations!
        Concepts
        _
        Co-Authors
        _
        Similar People
        _
        Same Department
        Physical Neighbors
        _

        This is an official Page/Publication of the University of Massachusetts Worcester Campus
        Office of the Vice Provost for Research, 55 Lake Ave North, Worcester, Massachusetts 01655
        Questions or Comments? Email: publicaffairs@umassmed.edu Phone: 508-856-1572