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    David Grunwald PhD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentBiochemistry and Molecular Pharmacology
    AddressAlbert Sherman Center
    368 Plantation Street
    Worcester MA 01605
    Phone774-455-3632
      Other Positions
      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentBiochemistry and Molecular Pharmacology

      InstitutionUMMS - Programs, Centers and Institutes
      DepartmentRNA Therapeutics Institute

        Bibliographic 
        selected publications
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        1. Nieuwenhuizen RP, Lidke KA, Bates M, Puig DL, Grünwald D, Stallinga S, Rieger B. Measuring image resolution in optical nanoscopy. Nat Methods. 2013 Jun; 10(6):557-62.
          View in: PubMed
        2. Singer S, Zhao R, Barsotti AM, Ouwehand A, Fazollahi M, Coutavas E, Breuhahn K, Neumann O, Longerich T, Pusterla T, Powers MA, Giles KM, Leedman PJ, Hess J, Grunwald D, Bussemaker HJ, Singer RH, Schirmacher P, Prives C. Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes. Mol Cell. 2012 Dec 14; 48(5):799-810.
          View in: PubMed
        3. Grünwald D, Singer RH. Multiscale dynamics in nucleocytoplasmic transport. Curr Opin Cell Biol. 2012 Feb; 24(1):100-6.
          View in: PubMed
        4. Grünwald D, Singer RH, Rout M. Nuclear export dynamics of RNA-protein complexes. Nature. 2011 Jul 21; 475(7356):333-41.
          View in: PubMed
        5. Lionnet T, Wu B, Grünwald D, Singer RH, Larson DR. Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression. Cold Spring Harb Symp Quant Biol. 2010; 75:113-26.
          View in: PubMed
        6. Dange T, Joseph A, Grünwald D. A perspective of the dynamic structure of the nucleus explored at the single-molecule level. Chromosome Res. 2011 Jan; 19(1):117-29.
          View in: PubMed
        7. Hocine S, Singer RH, Grünwald D. RNA processing and export. Cold Spring Harb Perspect Biol. 2010 Dec; 2(12):a000752.
          View in: PubMed
        8. Grünwald D, Singer RH. In vivo imaging of labelled endogenous ß-actin mRNA during nucleocytoplasmic transport. Nature. 2010 Sep 30; 467(7315):604-7.
          View in: PubMed
        9. Dange T, Grünwald D, Grünwald A, Peters R, Kubitscheck U. Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study. J Cell Biol. 2008 Oct 6; 183(1):77-86.
          View in: PubMed
        10. Grünwald D, Singer RH, Czaplinski K. Cell biology of mRNA decay. Methods Enzymol. 2008; 448:553-77.
          View in: PubMed
        11. Grünwald D, Shenoy SM, Burke S, Singer RH. Calibrating excitation light fluxes for quantitative light microscopy in cell biology. Nat Protoc. 2008; 3(11):1809-14.
          View in: PubMed
        12. Grünwald D, Martin RM, Buschmann V, Bazett-Jones DP, Leonhardt H, Kubitscheck U, Cardoso MC. Probing intranuclear environments at the single-molecule level. Biophys J. 2008 Apr 1; 94(7):2847-58.
          View in: PubMed
        13. Siebrasse JP, Grünwald D, Kubitscheck U. Single-molecule tracking in eukaryotic cell nuclei. Anal Bioanal Chem. 2007 Jan; 387(1):41-4.
          View in: PubMed
        14. Grünwald D, Spottke B, Buschmann V, Kubitscheck U. Intranuclear binding kinetics and mobility of single native U1 snRNP particles in living cells. Mol Biol Cell. 2006 Dec; 17(12):5017-27.
          View in: PubMed
        15. Grünwald D, Hoekstra A, Dange T, Buschmann V, Kubitscheck U. Direct observation of single protein molecules in aqueous solution. Chemphyschem. 2006 Apr 10; 7(4):812-5.
          View in: PubMed
        16. Grünwald D, Cardoso MC, Leonhardt H, Buschmann V. Diffusion and binding properties investigated by Fluorescence Correlation Spectroscopy (FCS). Curr Pharm Biotechnol. 2005 Oct; 6(5):381-6.
          View in: PubMed
        17. Kubitscheck U, Grünwald D, Hoekstra A, Rohleder D, Kues T, Siebrasse JP, Peters R. Nuclear transport of single molecules: dwell times at the nuclear pore complex. J Cell Biol. 2005 Jan 17; 168(2):233-43.
          View in: PubMed
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