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    David D McManus MD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentMedicine
    AddressUniversity of Massachusetts Medical School
    55 Lake Avenue North
    Worcester MA 01655
    Phone508-334-1000
      Other Positions
      InstitutionUMMS - School of Medicine
      DepartmentQuantitative Health Sciences

        Bibliographic 
        selected publications
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        1. Lubitz SA, Moser C, Sullivan L, Rienstra M, Fontes JD, Villalon ML, Pai M, McManus DD, Schnabel RB, Magnani JW, Yin X, Levy D, Pencina MJ, Larson MG, Ellinor PT, Benjamin EJ. Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community. J Am Heart Assoc. 2013; 2(5):e000126.
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        2. Darling CE, Fisher KA, McManus DD, Coles AH, Spencer FA, Gore JM, Goldberg RJ. Survival after hospital discharge for ST-segment elevation and non-ST-segment elevation acute myocardial infarction: a population-based study. Clin Epidemiol. 2013; 5:229-36.
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        3. Joffe SW, Webster K, McManus DD, Kiernan MS, Lessard D, Yarzebski J, Darling C, Gore JM, Goldberg RJ. Improved survival after heart failure: a community-based perspective. J Am Heart Assoc. 2013; 2(3):e000053.
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        4. McManus DD, Saczynski JS, Lessard D, Kinno M, Pidikiti R, Esa N, Harrington J, Goldberg RJ. Recent Trends in the Incidence, Treatment, and Prognosis of Patients With Heart Failure and Atrial Fibrillation (the Worcester Heart Failure Study). Am J Cardiol. 2013 May 15; 111(10):1460-5.
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        5. Smith DH, Thorp ML, Gurwitz JH, McManus DD, Goldberg RJ, Allen LA, Hsu G, Sung SH, Magid DJ, Go AS. Chronic Kidney Disease and Outcomes in Heart Failure With Preserved Versus Reduced Ejection Fraction: The Cardiovascular Research Network PRESERVE Study. Circ Cardiovasc Qual Outcomes. 2013 May 1; 6(3):333-42.
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        6. Joffe SW, Dewolf M, Shih J, McManus DD, Spencer FA, Lessard D, Gore JM, Goldberg RJ. Trends in the medical management of patients with heart failure. J Clin Med Res. 2013 Jun; 5(3):194-204.
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        7. Schnabel RB, Rienstra M, Sullivan LM, Sun JX, Moser CB, Levy D, Pencina MJ, Fontes JD, Magnani JW, McManus DD, Lubitz SA, Tadros TM, Wang TJ, Ellinor PT, Vasan RS, Benjamin EJ. Risk assessment for incident heart failure in individuals with atrial fibrillation. Eur J Heart Fail. 2013 Aug; 15(8):843-9.
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        8. Alonso A, Krijthe BP, Aspelund T, Stepas KA, Pencina MJ, Moser CB, Sinner MF, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Agarwal SK, McManus DD, Ellinor PT, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Soliman EZ, Stricker BH, Gudnason V, Heckbert SR, Benjamin EJ. Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE-AF Consortium. J Am Heart Assoc. 2013; 2(2):e000102.
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        9. Gurwitz JH, Magid DJ, Smith DH, Goldberg RJ, McManus DD, Allen LA, Saczynski JS, Thorp ML, Hsu G, Sung SH, Go AS. Contemporary prevalence and correlates of incident heart failure with preserved ejection fraction. Am J Med. 2013 May; 126(5):393-400.
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        10. Darling C, Saczynski JS, McManus DD, Lessard D, Spencer FA, Goldberg RJ. Delayed hospital presentation in acute decompensated heart failure: Clinical and patient reported factors. Heart Lung. 2013 Jul-Aug; 42(4):281-6.
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        11. Goldberg RJ, Gurwitz JH, Saczynski JS, Hsu G, McManus DD, Magid DJ, Smith DH, Go AS. Comparison of Medication Practices in Patients With Heart Failure and Preserved Versus Those With Reduced Ejection Fraction (from the Cardiovascular Research Network [CVRN]). Am J Cardiol. 2013 May 1; 111(9):1324-9.
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        12. Goldberg RJ, McManus DD, Allison J. Greater Knowledge and Appreciation of Commonly-used Research Study Designs. Am J Med. 2013 Feb; 126(2):169.e1-8.
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        13. McManus DD, Hsu G, Sung SH, Saczynski JS, Smith DH, Magid DJ, Gurwitz JH, Goldberg RJ, Go AS. Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction. J Am Heart Assoc. 2013; 2(1):e005694.
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        14. Saczynski JS, Go AS, Magid DJ, Smith DH, McManus DD, Allen L, Ogarek J, Goldberg RJ, Gurwitz JH. Patterns of Comorbidity in Older Adults with Heart Failure: The Cardiovascular Research Network PRESERVE Study. J Am Geriatr Soc. 2013 Jan; 61(1):26-33.
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        15. Awad HH, McManus DD, Anderson FA, Gore JM, Goldberg RJ. Young patients hospitalized with an acute coronary syndrome. Coron Artery Dis. 2013 Jan; 24(1):54-60.
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        16. McManus DD, Lee J, Maitas O, Esa N, Pidikiti R, Carlucci A, Harrington J, Mick E, Chon KH. A novel application for the detection of an irregular pulse using an iPhone 4S in patients with atrial fibrillation. Heart Rhythm. 2013 Mar; 10(3):315-9.
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        17. Shaikh AY, Maan A, Khan UA, Aurigemma GP, Hill JC, Kane JL, Tighe DA, Mick E, McManus DD. Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study. Cardiovasc Ultrasound. 2012; 10:48.
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        18. Shaikh AY, Maan A, Heist EK, Tighe DA, Aurigemma GP, McManus DD. Management strategies in atrial fibrillation in patients with heart failure. Cardiol Rev. 2012 Nov; 20(6):288-96.
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        19. McManus DD, Huang W, Domakonda KV, Ward J, Saczysnki JS, Gore JM, Goldberg RJ. Trends in atrial fibrillation in patients hospitalized with an acute coronary syndrome. Am J Med. 2012 Nov; 125(11):1076-84.
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        20. Saczynski JS, Gabbay E, McManus DD, McManus R, Gore JM, Gurwitz JH, Lessard D, Goldberg RJ. Increase in the proportion of patients hospitalized with acute myocardial infarction with do-not-resuscitate orders already in place between 2001 and 2007: a nonconcurrent prospective study. Clin Epidemiol. 2012; 4:267-74.
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        21. McManus DD, Rienstra M, Benjamin EJ. An update on the prognosis of patients with atrial fibrillation. Circulation. 2012 Sep 4; 126(10):e143-6.
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        22. Waring ME, McManus RH, Saczynski JS, Anatchkova MD, McManus DD, Devereaux RS, Goldberg RJ, Allison JJ, Kiefe CI. Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): design and rationale. Circ Cardiovasc Qual Outcomes. 2012 Sep 1; 5(5):e44-50.
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        23. Lee J, Reyes BA, McManus DD, Mathias O, Chon KH. Atrial fibrillation detection using a smart phone. Conf Proc IEEE Eng Med Biol Soc. 2012 Aug; 2012:1177-80.
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        24. Kaess BM, Enserro DM, McManus DD, Xanthakis V, Chen MH, Sullivan LM, Ingram C, O'Donnell CJ, Keaney JF, Vasan RS, Glazer NL. Cardiometabolic correlates and heritability of fetuin-a, retinol-binding protein 4, and Fatty-Acid binding protein 4 in the framingham heart study. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1943-7.
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        25. Lee J, Reyes BA, McManus DD, Mathias O, Chon KH. Atrial Fibrillation Detection Using an iPhone 4S. IEEE Trans Biomed Eng. 2013 Jan; 60(1):203-6.
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        26. Mick E, McManus DD, Goldberg RJ. Meta-analysis of increased heart rate and blood pressure associated with CNS stimulant treatment of ADHD in adults. Eur Neuropsychopharmacol. 2012 Jul 13.
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        27. Coles AH, Fisher KA, Darling C, McManus D, Maitas O, Yarzebski J, Gore JM, Lessard D, Goldberg RJ. Recent trends in post-discharge mortality among patients with an initial acute myocardial infarction. Am J Cardiol. 2012 Oct 15; 110(8):1073-7.
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        28. Cutrona SL, Toh S, Iyer A, Foy S, Daniel GW, Nair VP, Ng D, Butler MG, Boudreau D, Forrow S, Goldberg R, Gore J, McManus D, Racoosin JA, Gurwitz JH. Validation of acute myocardial infarction in the Food and Drug Administration's Mini-Sentinel program. Pharmacoepidemiol Drug Saf. 2013 Jan; 22(1):40-54.
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        29. Rienstra M, McManus DD, Benjamin EJ. Novel risk factors for atrial fibrillation: useful for risk prediction and clinical decision making? Circulation. 2012 May 22; 125(20):e941-6.
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        30. McManus DD, Nguyen HL, Saczynski JS, Tisminetzky M, Bourell P, Goldberg RJ. Multiple cardiovascular comorbidities and acute myocardial infarction: temporal trends (1990-2007) and impact on death rates at 30 days and 1 year. Clin Epidemiol. 2012; 4:115-23.
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        31. McManus DD, Aslam F, Goyal P, Goldberg RJ, Huang W, Gore JM. Incidence, prognosis, and factors associated with cardiac arrest in patients hospitalized with acute coronary syndromes (the Global Registry of Acute Coronary Events Registry). Coron Artery Dis. 2012 Mar; 23(2):105-12.
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        32. Ward J, Szabo G, McManus D, Boyer E. Advanced molecular biologic techniques in toxicologic disease. J Med Toxicol. 2011 Dec; 7(4):288-94.
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        33. Park D, McManus D, Darling C, Goldberg JH, Gore JM, Lessard D, Goldberg RJ. Recent trends in the characteristics and prognosis of patients hospitalized with acute heart failure. Clin Epidemiol. 2011; 3:295-303.
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        34. Lee J, McManus DD, Merchant S, Chon KH. Automatic Motion and Noise Artifact Detection in Holter ECG Data Using Empirical Mode Decomposition and Statistical Approaches. IEEE Trans Biomed Eng. 2012 Jun; 59(6):1499-506.
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        35. Magnani JW, Rienstra M, Lin H, Sinner MF, Lubitz SA, McManus DD, Dupuis J, Ellinor PT, Benjamin EJ. Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation. 2011 Nov 1; 124(18):1982-93.
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        36. McManus DD, Ambros V. Circulating MicroRNAs in cardiovascular disease. Circulation. 2011 Nov 1; 124(18):1908-10.
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        37. Waring ME, Saczynski JS, McManus D, Zacharias M, Lessard D, Gore JM, Goldberg RJ. Weight and Mortality Following Heart Failure Hospitalization among Diabetic Patients. Am J Med. 2011 Sep; 124(9):834-40.
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        38. McManus DD, Piacentine SM, Lessard D, Gore JM, Yarzebski J, Spencer FA, Goldberg RJ. Thirty-year (1975 to 2005) trends in the incidence rates, clinical features, treatment practices, and short-term outcomes of patients <55 years of age hospitalized with an initial acute myocardial infarction. Am J Cardiol. 2011 Aug 15; 108(4):477-82.
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        39. Barringhaus KG, Park KL, McManus DD, Steg PG, Montalescot G, Van de Werf F, López-Sendón J, FitzGerald G, Gore JM. Outcomes from patients with Multi-Vessel disease following primary PCI: staged PCI imparts very low mortality. Catheter Cardiovasc Interv. 2011 Apr 1; 77(5):617-22.
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        40. McManus DD, Shaikh AY, Abhishek F, Vasan RS. Atrial fibrillation and heart failure parallels: lessons for atrial fibrillation prevention. Crit Pathw Cardiol. 2011 Mar; 10(1):46-51.
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        41. McManus DD, Lyass A, Ingelsson E, Massaro JM, Meigs JB, Aragam J, Benjamin EJ, Vasan RS. Relations of circulating resistin and adiponectin and cardiac structure and function: the framingham offspring study. Obesity (Silver Spring). 2012 Sep; 20(9):1882-6.
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        42. McManus DD, Chinali M, Saczynski JS, Gore JM, Yarzebski J, Spencer FA, Lessard D, Goldberg RJ. 30-year trends in heart failure in patients hospitalized with acute myocardial infarction. Am J Cardiol. 2011 Feb 1; 107(3):353-9.
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        43. McManus DD, Gore J, Yarzebski J, Spencer F, Lessard D, Goldberg RJ. Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI. Am J Med. 2011 Jan; 124(1):40-7.
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        44. Santolucito PA, Tighe DA, McManus DD, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Management and outcomes of renal disease and acute myocardial infarction. Am J Med. 2010 Sep; 123(9):847-55.
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        45. McManus DD, Xanthakis V, Sullivan LM, Zachariah J, Aragam J, Larson MG, Benjamin EJ, Vasan RS. Longitudinal tracking of left atrial diameter over the adult life course: Clinical correlates in the community. Circulation. 2010 Feb 9; 121(5):667-74.
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        46. McManus DD, Corteville DC, Shlipak MG, Whooley MA, Ix JH. Relation of kidney function and albuminuria with atrial fibrillation (from the Heart and Soul Study). Am J Cardiol. 2009 Dec 1; 104(11):1551-5.
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        47. Turakhia MP, McManus DD, Whooley MA, Schiller NB. Increase in end-systolic volume after exercise independently predicts mortality in patients with coronary heart disease: data from the Heart and Soul Study. Eur Heart J. 2009 Oct; 30(20):2478-84.
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        48. McManus DD, Mattei ML, Rose K, Rashkin J, Rosenthal LS. Inadvertent lead placement in the left ventricle: a case report and brief review. Indian Pacing Electrophysiol J. 2009; 9(4):224-8.
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        49. Saczynski JS, McManus D, Zhou Z, Spencer F, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Trends in atrial fibrillation complicating acute myocardial infarction. Am J Cardiol. 2009 Jul 15; 104(2):169-74.
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        50. McManus DD, Rosenthal LS, Robotis DA. Inappropriate shock from nonphysiologic noise during implantation of a Boston Scientific COGNIS N119 biventricular implantable cardioverter-defibrillator (CRT-D). Heart Rhythm. 2009 Jul; 6(7):1066-8.
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        51. McManus DD, Shah SJ, Fabi MR, Rosen A, Whooley MA, Schiller NB. Prognostic value of left ventricular end-systolic volume index as a predictor of heart failure hospitalization in stable coronary artery disease: data from the Heart and Soul Study. J Am Soc Echocardiogr. 2009 Feb; 22(2):190-7.
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        52. McManus DD, Ockene IS. Brief supported lifestyle counseling: modest interventions yield modest effects. Arch Intern Med. 2008 Jan 28; 168(2):129-30.
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        53. McManus D, Shlipak M, Ix JH, Ali S, Whooley MA. Association of cystatin C with poor exercise capacity and heart rate recovery: data from the heart and soul study. Am J Kidney Dis. 2007 Mar; 49(3):365-72.
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        54. Hsue PY, McManus D, Selby V, Ren X, Pillutla P, Younes N, Goldschlager N, Waters DD. Cardiac arrest in patients who smoke crack cocaine. Am J Cardiol. 2007 Mar 15; 99(6):822-4.
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        55. McManus D, Pipkin SS, Whooley MA. Screening for depression in patients with coronary heart disease (data from the Heart and Soul Study). Am J Cardiol. 2005 Oct 15; 96(8):1076-81.
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