Frailty

"Frailty" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A state of increased vulnerability to stressors, following declines in function and reserves across multiple physiologic systems, characterized by MUSCLE WEAKNESS; FATIGUE; slowed motor performance; low physical activity; and unintentional weight loss.

Descriptor ID	D000073496
MeSH Number(s)	C23.550.359
Concept/Terms	Frailty Frailty Frailties Frailness Frailty Syndrome Frailty Syndrome Syndrome, Frailty Syndromes, Frailty

Below are MeSH descriptors whose meaning is more general than "Frailty".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Frailty [C23.550.359]

Below are MeSH descriptors whose meaning is related to "Frailty".

Below are MeSH descriptors whose meaning is more specific than "Frailty".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Frailty" by people in this website by year, and whether "Frailty" was a major or minor topic of these publications.

Bar chart showing 53 publications over 11 distinct years, with a maximum of 14 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2016	1	0	1
2017	2	1	3
2018	4	0	4
2019	3	0	3
2020	6	0	6
2021	7	0	7
2022	14	0	14
2023	6	0	6
2024	2	2	4
2025	1	0	1
2026	4	0	4

Below are the most recent publications written about "Frailty" by people in Profiles.

Mian H, Faisal MS, Chen T, Brazauskas R, Oloyede T, Ahmed N, Afrough A, Anderson LD, Banerjee R, Berdeja J, Bidikian A, Devos J, Dhakal B, Dias A, Dima D, Efebera YA, Gowda L, Hansen DK, Hashmi H, Landau HJ, Lekakis L, Mirza AS, Narra R, Patel K, Rosko AE, Schroeder M, Sidana S, Usmani S, Pasquini MC, Nishihori T, Akhtar OS, Mohan M. Efficacy and safety of frail patients treated with ciltacabtagene autoleucel in the real world: A Center for International Blood and Marrow Transplant Research analysis. Cancer. 2026 Oct 01; 132(19):e70614.

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Ghazzal BZ, Lessard D, Tejan J, Otabil EM, Doerr A, Nagy NY, Harrington DJ, Montenario M, Saczynski JS, McManus DD. Recurrence or persistence of atrial fibrillation is associated with frailty and adverse outcomes: the SAGE-AF cohort study. BMC Geriatr. 2026 06 13; 26(1).

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Reddington H, Shafique S, Palleiko B, Bludevich B, Crawford A, Maxfield M, Uy KF, Emmerick ICM, Lou F. The Modified Frailty Index and Its Association With Esophagectomy Outcomes. J Surg Res. 2026 Aug; 324:20-26.

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Buchholz EJ, Reynolds CA, Bell TR, Williams ME, Tang R, Panizzon MS, Lyons MJ, Jak AJ, Hunt JFV, Gillespie NA, Fennema-Notestine C, Elman JA, Kremen WS, Franz CE. Mediators of attachment, frailty, and mild cognitive impairment in older adults. Health Psychol. 2026 Sep; 45(9):952-961.

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Adegbite B, Tan CR, Shekarkhand T, Firestone RS, Jurgens EM, Miller K, Lesokhin AM, Shah GL, Korde N, Rajeeve S, Landau HJ, Scordo M, Hassoun H, Maclachlan KH, Shah UA, Hultcrantz M, Hamadeh IS, Derkach A, Nemirovsky D, Giralt SA, Mailankody S, Usmani SZ, Hashmi H. Outcomes in frail patients receiving BCMA-directed bispecific antibodies for relapsed/refractory multiple myeloma. Blood Adv. 2025 Aug 12; 9(15):4016-4022.

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Yuan Y, Barooah A, Lapane KL, Mack D, Rothschild AJ, Ulbricht CM. Health Profile Transitions and the Association With Cognitive Impairment in Older Nursing Home Residents With Suicidal Ideation. Int J Geriatr Psychiatry. 2024 10; 39(10):e70003.

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Shi SM, Olivieri-Mui B, Park CM, Sison S, McCarthy EP, Kim DH. Frailty in Medicare Advantage Beneficiaries and Traditional Medicare Beneficiaries. JAMA Netw Open. 2024 08 01; 7(8):e2431067.

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Athreya DS, Saczynski JS, Gurwitz JH, Monahan KM, Bamgbade BA, Paul TJ, Sogade F, Lessard DM, McManus DD, Helm RH. Cognitive impairment and treatment strategy for atrial fibrillation in older adults: The SAGE-AF study. J Am Geriatr Soc. 2024 07; 72(7):2082-2090.

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Buchholz E, Gillespie NA, Hunt JF, Reynolds CA, Rissman RA, Schroeder A, Cortes I, Bell T, Lyons MJ, Kremen WS, Franz CE. Midlife cumulative deficit frailty predicts Alzheimer's disease-related plasma biomarkers in older adults. Age Ageing. 2024 03 01; 53(3).

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Xu EJ, Kyriazis P, Pawar A, Pavlakis M, Aala A. Frailty and Kidney Transplant Waitlisting: A Single-Center Experience. Transplant Proc. 2024 Jan-Feb; 56(1):37-43.

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