Cognitive Dysfunction

"Cognitive Dysfunction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Diminished or impaired mental and/or intellectual function.

Descriptor ID	D060825
MeSH Number(s)	F03.615.250.700
Concept/Terms	Cognitive Dysfunction Cognitive Dysfunction Cognitive Dysfunctions Dysfunction, Cognitive Dysfunctions, Cognitive Cognitive Impairments Cognitive Impairment Impairment, Cognitive Impairments, Cognitive Mild Cognitive Impairment Mild Cognitive Impairment Cognitive Impairment, Mild Cognitive Impairments, Mild Impairment, Mild Cognitive Impairments, Mild Cognitive Mild Cognitive Impairments Mild Neurocognitive Disorder Disorder, Mild Neurocognitive Disorders, Mild Neurocognitive Mild Neurocognitive Disorders Neurocognitive Disorder, Mild Neurocognitive Disorders, Mild Cognitive Decline Cognitive Decline Cognitive Declines Decline, Cognitive Declines, Cognitive Mental Deterioration Deterioration, Mental Deteriorations, Mental Mental Deteriorations

Below are MeSH descriptors whose meaning is more general than "Cognitive Dysfunction".

Psychiatry and Psychology [F]
Mental Disorders [F03]
Neurocognitive Disorders [F03.615]
Cognition Disorders [F03.615.250]
Cognitive Dysfunction [F03.615.250.700]

Below are MeSH descriptors whose meaning is related to "Cognitive Dysfunction".

Below are MeSH descriptors whose meaning is more specific than "Cognitive Dysfunction".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cognitive Dysfunction" by people in this website by year, and whether "Cognitive Dysfunction" was a major or minor topic of these publications.

Bar chart showing 295 publications over 16 distinct years, with a maximum of 45 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	0	1	1
2012	3	2	5
2013	3	1	4
2014	6	1	7
2015	4	0	4
2016	6	0	6
2017	18	2	20
2018	21	4	25
2019	24	4	28
2020	32	5	37
2021	24	6	30
2022	28	2	30
2023	24	1	25
2024	33	12	45
2025	16	6	22
2026	5	1	6

Below are the most recent publications written about "Cognitive Dysfunction" by people in Profiles.

Fu C, Ye K, Qiu Z, Hu X, Wang X, Xiao H. Agaricus bisporus polysaccharides alleviate high-fat diet-induced cognitive impairment via microbiota-gut-brain axis modulation. Food Res Int. 2026 Nov 01; 243(Pt 1):120317.

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Zeamer AL, Lai Y, Loew E, Sanborn V, Tracy M, Jo C, Ferdinand D, Ward DV, Bhattarai SK, Drake J, McCormick BA, Bucci V, Haran JP. Microbiome functional gene pathways are indicative of cognitive performance in older adults at risk for Alzheimer's disease. Gut Microbes. 2026 Dec 31; 18(1):2676162.

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Buchholz EJ, Reynolds CA, Bell TR, Williams ME, Tang R, Panizzon MS, Lyons MJ, Jak AJ, Hunt JFV, Gillespie NA, Fennema-Notestine C, Elman JA, Kremen WS, Franz CE. Mediators of attachment, frailty, and mild cognitive impairment in older adults. Health Psychol. 2026 Sep; 45(9):952-961.

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Li T, Castro-Gomez S, Botella Lucena P, Vieira-Saecker A, Schwartz S, Ding Y, Deng Y, Gou M, Stein V, Golenbock DT, Latz E, Heneka MT. Inflammasome adaptor ASC promotes sustained neuroinflammation and mild cognitive impairment in a closed-head injury model. J Clin Invest. 2026 Apr 01; 136(7).

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Gifford KA, Rong J, Schramm E, Zhang Y, Pathiravasan CH, Benjamin EJ, Lin H, Liu C, Au R, Libon DJ, Murabito JM. Digital Stroop Test as a neurocognitive marker in a community-based sample of older adults: Data from the Framingham Heart Study. J Alzheimers Dis. 2026 03; 110(1):463-470.

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Cánovas R, Cox T, Doré V, Bourgeat P, Fripp J, Feizpour A, Shishegar R, Fowler CJ, Laws SM, Porter T, Rainey-Smith S, Shaw LM, Bateman RJ, Li Y, Vitaliy O, Weiner MW, Morris JC, Benzinger TLS, Schindler SE, Nakamura A, Iwatsubo T, Ikeuchi T, Kato T, Maruff P, Sohrabi HR, Rowe CC, Martins RN, Masters CL, Doecke JD. When Does Alzheimer's Disease Start? Plasma A?42/40 Assays Show Steep Changes at A?-PET Centiloid 15, Mean Age of 66?Years. Ann Neurol. 2026 May; 99(5):1327-1342.

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Sabbagh MN, Cummings JL, Ballard C, van der Flier WM, Heneka MT, Holst JJ, Knudsen LB, Salloway S, Tansey MG, Drucker DJ. Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders. Nat Aging. 2026 Jan; 6(1):56-67.

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Bentvelzen AC, Kochan NA, Saks DG, Chander RJ, Koncz R, Aam S, Alves GS, Briceno EM, Brodtmann A, Cerami C, Clancy U, Cysique L, Deary IJ, DeCarli C, Dodich A, Godefroy O, Jochems ACC, Jokinen H, Kang Y, Karayanidis F, Kessels RPC, Kyläheiko I, Lancaster K, Laukka EJ, Levine DA, Marseglia A, Pase MP, Peters R, Salmon DP, Salvadori E, Shirk SD, Stokes KA, Sudo FK, Summers MJ, Vandermorris S, Vasquez BP, Sachdev PS. Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia. JAMA Netw Open. 2025 12 01; 8(12):e2547948.

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Banerjee A, Yang F, Dutta J, Cacciola A, Hornberger M, Saranathan M. Atrophy patterns of deep gray matter nuclei in Alzheimer's disease and frontotemporal dementia. J Alzheimers Dis. 2025 12; 108(4):1760-1777.

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Fink A, Reinke C, Aretz B, Heneka MT, Doblhammer G. Can vigorous physical activity mitigate the effect of systemic inflammation on cognitive performance? Results from a large older community dwelling population in The Netherlands. J Alzheimers Dis. 2025 12; 108(3):1369-1377.

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