Below are the most recent publications written about "Microglia" by people in Profiles.
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Schafer DP, Stevens B, Bennett ML, Bennett FC. Role of Microglia in Central Nervous System Development and Plasticity. Cold Spring Harb Perspect Biol. 2025 Oct 01; 17(10).
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Faust TE, Lee YH, O'Connor CD, Boyle MA, Gunner G, Dur?n-Laforet V, Ferrari LL, Murphy RE, Badimon A, Sakers K, Eroglu C, Ayata P, Schaefer A, Schafer DP. Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling. Cell. 2025 Sep 18; 188(19):5212-5230.e21.
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Miao G, Fortier TM, Liu H, Schafer DP, Fitzgerald KA, Mao J, Baehrecke EH. Microglia promote inflammatory cell death upon neuronal mitochondrial impairment during neurodegeneration. Nat Struct Mol Biol. 2025 Oct; 32(10):2046-2059.
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Liu S, Li L, Zhang F, Garcia-Corral M, Meyer K, Fortuna PRJ, van Sambeek B, Appleton E, Ng AHM, Khoshakhlagh P, Lu YR, Cameron J, Ramirez RN, Chen Y, Wu CT, Huang JY, Tan Y, Chao G, Aach J, Lim ET, Tam JM, Raychaudhuri S, Church GM. Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC. Nat Commun. 2025 Jun 10; 16(1):5136.
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Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.
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Baker V, Budinger D, Riechers SP, Heneka MT. Protocol for observing tunneling nanotube formation and function in both fixed and live primary mouse neurons and microglia coculture system. STAR Protoc. 2025 Jun 20; 6(2):103723.
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Gross PS, Dur?n-Laforet V, Ho LT, Melchor GS, Zia S, Manavi Z, Barclay WE, Lee SH, Shults N, Selva S, Alvarez E, Plemel JR, Fu MM, Schafer DP, Huang JK. Senescent-like microglia limit remyelination through the senescence associated secretory phenotype. Nat Commun. 2025 Mar 07; 16(1):2283.
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Lin JP, Brake A, Donadieu M, Lee A, Smith G, Hu K, Nair G, Kawaguchi R, Sati P, Geschwind DH, Jacobson S, Schafer DP, Reich DS. 4D marmoset brain map reveals MRI and molecular signatures for onset of multiple sclerosis-like lesions. Science. 2025 Feb 28; 387(6737):eadp6325.
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Lonkar N, Latz E, McManus RM. Neuroinflammation and immunometabolism in neurodegenerative diseases. Curr Opin Neurol. 2025 Apr 01; 38(2):163-171.
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McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.