Astrocytes

"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.

Descriptor ID	D001253
MeSH Number(s)	A08.637.200 A11.650.200
Concept/Terms	Astrocytes Astrocytes Astrocyte Astroglia Astroglias

Below are MeSH descriptors whose meaning is more general than "Astrocytes".

Anatomy [A]
Nervous System [A08]
Neuroglia [A08.637]
Astrocytes [A08.637.200]
Cells [A11]
Neuroglia [A11.650]
Astrocytes [A11.650.200]

Below are MeSH descriptors whose meaning is related to "Astrocytes".

Below are MeSH descriptors whose meaning is more specific than "Astrocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.

Bar chart showing 89 publications over 24 distinct years, with a maximum of 9 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2000	1	2	3
2002	4	0	4
2003	1	3	4
2004	1	0	1
2005	0	3	3
2006	1	3	4
2008	5	1	6
2009	1	0	1
2010	1	0	1
2011	4	2	6
2013	1	1	2
2014	1	4	5
2015	1	3	4
2016	1	2	3
2017	3	0	3
2018	1	6	7
2019	0	1	1
2020	3	4	7
2021	4	5	9
2022	3	4	7
2023	0	1	1
2024	2	3	5
2025	1	0	1

Below are the most recent publications written about "Astrocytes" by people in Profiles.

Lin JP, Brake A, Donadieu M, Lee A, Smith G, Hu K, Nair G, Kawaguchi R, Sati P, Geschwind DH, Jacobson S, Schafer DP, Reich DS. 4D marmoset brain map reveals MRI and molecular signatures for onset of multiple sclerosis-like lesions. Science. 2025 Feb 28; 387(6737):eadp6325.

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Petersen N, McCann KE, Stavarache MA, Kim LY, Weinshenker D, Winder DG. Adenosine A2A Receptors Link Astrocytic a1-Adrenergic Signaling to Wake-Promoting Dopamine Neurons. Biol Psychiatry. 2025 May 01; 97(9):915-928.

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Botella Lucena P, Heneka MT. Inflammatory aspects of Alzheimer's disease. Acta Neuropathol. 2024 Aug 28; 148(1):31.

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Hochbaum DR, Hulshof L, Urke A, Wang W, Dubinsky AC, Farnsworth HC, Hakim R, Lin S, Kleinberg G, Robertson K, Park C, Solberg A, Yang Y, Baynard C, Nadaf NM, Beron CC, Girasole AE, Chantranupong L, Cortopassi MD, Prouty S, Geistlinger L, Banks AS, Scanlan TS, Datta SR, Greenberg ME, Boulting GL, Macosko EZ, Sabatini BL. Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration. Cell. 2024 Oct 03; 187(20):5679-5697.e23.

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Biswas DD, Shi Y, El Haddad L, Sethi R, Huston M, Kehoe S, Scarrow ER, Strickland LM, Pucci LA, Dhindsa JS, Hunanyan A, La Spada AR, ElMallah MK. Respiratory neuropathology in spinocerebellar ataxia type 7. JCI Insight. 2024 Jul 18; 9(18).

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Huber RE, Babbitt C, Peyton SR. Heterogeneity of brain extracellular matrix and astrocyte activation. J Neurosci Res. 2024 May; 102(5):e25356.

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P?rez-N??ez R, Chamorro A, Gonz?lez MF, Contreras P, Artigas R, Corval?n AH, van Zundert B, Reyes C, Moya PR, Avalos AM, Schneider P, Quest AFG, Leyton L. Protein kinase B (AKT) upregulation and Thy-1-av?3?integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis. J Neuroinflammation. 2023 Jan 06; 20(1):5.

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Henning L, Antony H, Breuer A, M?ller J, Seifert G, Audinat E, Singh P, Brosseron F, Heneka MT, Steinh?user C, Bedner P. Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy. Glia. 2023 02; 71(2):168-186.

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de Oliveira LG, de Souza Angelo Y, Yamamoto P, Carregari VC, Crunfli F, Reis-de-Oliveira G, Costa L, Vendramini PH, Duque ?A, Dos Santos NB, Firmino EM, Paiva IM, Almeida GM, Sebollela A, Polonio CM, Zanluqui NG, de Oliveira MG, da Silva P, Davanzo GG, Ayupe MC, Salgado CL, de Souza Filho AF, de Ara?jo MV, Silva-Pereira TT, de Almeida Campos AC, G?es LGB, Dos Passos Cunha M, Caldini EG, D'Imp?rio Lima MR, Fonseca DM, de S? Guimar?es AM, Minoprio PC, Munhoz CD, Mori CMC, Moraes-Vieira PM, Cunha TM, Martins-de-Souza D, Peron JPS. SARS-CoV-2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes. J Neurochem. 2022 10; 163(2):113-132.

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Chaturvedi R, Stork T, Yuan C, Freeman MR, Emery P. Astrocytic GABA transporter controls sleep by modulating GABAergic signaling in Drosophila circadian neurons. Curr Biol. 2022 05 09; 32(9):1895-1908.e5.

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