Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Li T, Castro-Gomez S, Botella Lucena P, Vieira-Saecker A, Schwartz S, Ding Y, Deng Y, Gou M, Stein V, Golenbock DT, Latz E, Heneka MT. Inflammasome adaptor ASC promotes sustained neuroinflammation and mild cognitive impairment in a closed-head injury model. J Clin Invest. 2026 Apr 01; 136(7).
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de Farias IS, Duarte-Barbosa M, Salazar N, Andreata-Santos R, de Lucena VWL, Maricato JT, Gazzinelli RT, Janini LMR, Bortoluci KR. NLRP3 inflammasome activation in astrocytes restricts SARS-CoV-2 through gasdermin-D-driven IL-1? release. Front Immunol. 2025; 16:1703765.
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Ravichandran KA, Brosseron F, McManus RM, Ising C, G?rgen S, Schmidt SV, Santarelli F, Lee SY, Jung H, Chung WS, Kim CH, Ruiz Laza A, Ruiz de Almod?var C, Ramirez A, Latz E, Heneka MT. Enhancing Tyro3 signaling ameliorates IL-1? production through STAT1 in Alzheimer's disease models. J Leukoc Biol. 2025 Dec 01; 117(12).
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Koerber RM, Krollmann C, Cieslak K, Tregel E, Saenz ML, Br?mmendorf TH, Koschmieder S, Griesshammer M, G?tgemann I, Baldauf CK, Fischer T, Brossart P, Kolbe CC, Latz E, Wolf D, Teichmann LL. NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms. Nat Commun. 2025 Nov 26; 16(1):10591.
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Krause K, Franch Arroyo S, Ugolini M, Kueck T, Sullivan TJ, G?lvez EJC, Muenzner M, Goosmann C, Brinkmann V, Frese CK, Alagesan K, Vierbuchen T, Heine H, Resch U, Sander LE, Charpentier E. Streptococcus pyogenes EVs induce the alternative inflammasome via caspase-4/-5 in human monocytes. EMBO Rep. 2025 Oct; 26(19):4847-4885.
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Weber ANR, McManus RM, Hornung V, Geyer M, Kuemmerle-Deschner JB, Latz E. The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets. Nat Immunol. 2025 Sep; 26(9):1453-1466.
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Brezani V, Joshi RS, Ortega-Ribera M, Nagesh PT, Brezani V, Zivny A, Kurt-Jones EA, Golenbock DT, Szabo G. Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer's disease associated with inflammasome activation and ASC speck propagation. J Neuroinflammation. 2025 Jul 15; 22(1):183.
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Dehdashtian E, Caricchio R. From innate immunity to autoimmunity: Neutrophils in systemic lupus erythematosus pathogenesis. Lupus. 2025 Sep; 34(10):989-1002.
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Cahill S, Humphries F. Inflammasomopathies: mechanisms and disease signatures. Trends Immunol. 2025 May; 46(5):372-385.
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Mishra N, Mohs M, Wittmann N, Gross S, Thompson PR, Bossaller L. PLC and PAD2 Regulate Extracellular Calcium-Triggered Release of Macrophage Extracellular DNA Traps. Eur J Immunol. 2025 Apr; 55(4):e202350942.