Immunity, Innate

"Immunity, Innate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.

Descriptor ID	D007113
MeSH Number(s)	G12.450.564
Concept/Terms	Immunity, Innate Immunity, Innate Immunity, Non-Specific Immunity, Non Specific Non-Specific Immunity Innate Immune Response Immune Response, Innate Immune Responses, Innate Innate Immune Responses Immunity, Native Native Immunity Innate Immunity Immunity, Natural Natural Immunity Resistance, Natural Resistance, Natural Natural Resistance

Below are MeSH descriptors whose meaning is more general than "Immunity, Innate".

Biological Sciences [G]
Immune System Phenomena [G12]
Immunity [G12.450]
Immunity, Innate [G12.450.564]

Below are MeSH descriptors whose meaning is related to "Immunity, Innate".

Below are MeSH descriptors whose meaning is more specific than "Immunity, Innate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunity, Innate" by people in this website by year, and whether "Immunity, Innate" was a major or minor topic of these publications.

Bar chart showing 581 publications over 31 distinct years, with a maximum of 43 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	2	3
1997	0	1	1
1998	0	2	2
1999	1	3	4
2000	0	5	5
2001	0	9	9
2002	0	4	4
2003	2	8	10
2004	6	7	13
2005	5	13	18
2006	6	12	18
2007	14	6	20
2008	16	11	27
2009	12	11	23
2010	10	21	31
2011	22	14	36
2012	23	20	43
2013	19	15	34
2014	21	13	34
2015	17	8	25
2016	14	21	35
2017	12	15	27
2018	14	12	26
2019	9	19	28
2020	14	10	24
2021	11	6	17
2022	4	8	12
2023	1	17	18
2024	14	8	22
2025	7	4	11
2026	1	0	1

Below are the most recent publications written about "Immunity, Innate" by people in Profiles.

Merbecks AJ, Mennicken C, de Graaf DM, Shkarina K, Wagner T, Latz E. Western lifestyle linked to maladaptive trained immunity. Elife. 2026 Jan 21; 15.

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Basham KJ, Ward RA, Vyas JM, Nolling Jensen K. Immunomodulatory functions of fungal melanins in respiratory infections. mBio. 2026 Jan 14; 17(1):e0214125.

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Bridges K, Awany D, Gela A, Mwambene TD, Kurtz SL, Baker RE, Elkins KL, Sassetti CM, Scriba TJ, Lauffenburger DA. Cross-species blood transcriptional correlates of BCG-mediated protection against tuberculosis include innate and adaptive immune processes. JCI Insight. 2025 Dec 22; 10(24).

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Dehdashtian E, Caricchio R. From innate immunity to autoimmunity: Neutrophils in systemic lupus erythematosus pathogenesis. Lupus. 2025 Sep; 34(10):989-1002.

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Grace PS, Peters JM, Sixsmith J, Lu R, Irvine EB, Luedeman C, Fenderson BA, Vickers A, Slein MD, McKitrick T, Wei MH, Cummings RD, Wallace A, Cavacini LA, Choudhary A, Proulx MK, Sundling C, K?llenius G, Reljic R, Ernst JD, Casadevall A, Locht C, Pinter A, Sassetti CM, Bryson BD, Fortune SM, Alter G. Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction. Immunity. 2025 Jun 10; 58(6):1586-1597.e5.

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Kwaku GN, Jensen KN, Simaku P, Floyd DJ, Saelens JW, Reardon CM, Ward RA, Basham KJ, Hepworth OW, Vyas TD, Zamith-Miranda D, Nosanchuk JD, Vyas JM, Brown Harding H. Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation. PLoS Pathog. 2025 May; 21(5):e1012879.

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Wani KA, Pukkila-Worley R. Evolutionarily ancient functions of enzymatic TIR proteins in innate immunity. Trends Immunol. 2025 Jun; 46(6):441-454.

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Anterasian C, Gela A, Mwambene TD, Shah JA, Ivie J, Dill-McFarland KA, Hanekom WA, Kiritsy MC, Sassetti CM, Musvosvi M, Hatherill M, Scriba TJ, Hawn TR. BCG induced innate immune response heterogeneity and susceptibility to pediatric tuberculosis. J Immunol. 2025 May 01; 214(5):936-946.

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Thong PM, Wong YH, Kornfeld H, Goletti D, Ong CWM. Immune dysregulation of diabetes in tuberculosis. Semin Immunol. 2025 06; 78:101959.

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Tse-Kang S, Wani KA, Pukkila-Worley R. Patterns of pathogenesis in innate immunity: insights from C. elegans. Nat Rev Immunol. 2025 Sep; 25(9):637-648.

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