Below are the most recent publications written about "NLR Family, Pyrin Domain-Containing 3 Protein" by people in Profiles.
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Weber ANR, McManus RM, Hornung V, Geyer M, Kuemmerle-Deschner JB, Latz E. The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets. Nat Immunol. 2025 Sep; 26(9):1453-1466.
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Brezani V, Joshi RS, Ortega-Ribera M, Nagesh PT, Brezani V, Zivny A, Kurt-Jones EA, Golenbock DT, Szabo G. Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer's disease associated with inflammasome activation and ASC speck propagation. J Neuroinflammation. 2025 Jul 15; 22(1):183.
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Dehdashtian E, Caricchio R. From innate immunity to autoimmunity: Neutrophils in systemic lupus erythematosus pathogenesis. Lupus. 2025 Sep; 34(10):989-1002.
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McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.
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Lynn T, Kelleher ME, Georges HM, McCauley EM, Logan RW, Yonkers KA, Abrahams VM. Buprenorphine induces human fetal membrane sterile inflammation. J Reprod Immunol. 2025 Mar; 168:104445.
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Surve D, Fish A, Debnath M, Pinjari A, Lorenzana A, Piya S, Peyton S, Kulkarni A. Sprayable inflammasome-inhibiting lipid nanorods in a polymeric scaffold for psoriasis therapy. Nat Commun. 2024 10 19; 15(1):9035.
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Babuta M, Morel C, de Carvalho Ribeiro M, Calenda C, Ortega-Ribera M, Thevkar Nagesh P, Copeland C, Zhuang Y, Wang Y, Cho Y, Joshi R, Brezani V, Hawryluk D, Datta AA, Mehta J, Nasser I, Szabo G. Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis. Gut. 2024 Oct 07; 73(11):1854-1869.
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Karabag D, Heneka MT, Ising C. The putative contribution of cellular senescence to driving tauopathies. Trends Immunol. 2024 10; 45(10):837-848.
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Weiss FD, Alvarez Y, Shakeri F, Sahu A, Leka P, Dernst A, Rollheiser J, Vasconcelos M, Geraci A, Duthie F, Stahl R, Lee HE, Gellner AK, Buness A, Latz E, Meissner F. Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice. Cell Death Differ. 2024 Dec; 31(12):1717-1729.
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Wang W, Dernst A, Martin B, Lorenzi L, Cadefau-Fabregat M, Phulphagar K, Wagener A, Budden C, Stair N, Wagner T, F?rber H, Jaensch A, Stahl R, Duthie F, Schmidt SV, Coll RC, Meissner F, Cuartero S, Latz E, Mangan MSJ. Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation. Cell Rep. 2024 09 24; 43(9):114736.