Amyloid

"Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.

Descriptor ID	D000682
MeSH Number(s)	D05.500.049 D12.776.049
Concept/Terms	Amyloid Amyloid Amyloid Substance Substance, Amyloid Amyloid Fibrils Amyloid Fibrils Fibrils, Amyloid

Below are MeSH descriptors whose meaning is more general than "Amyloid".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Amyloid [D05.500.049]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Amyloid [D12.776.049]

Below are MeSH descriptors whose meaning is related to "Amyloid".

Below are MeSH descriptors whose meaning is more specific than "Amyloid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Amyloid" by people in this website by year, and whether "Amyloid" was a major or minor topic of these publications.

Bar chart showing 49 publications over 22 distinct years, with a maximum of 6 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2002	0	1	1
2003	0	1	1
2004	0	1	1
2005	1	0	1
2006	1	2	3
2007	3	0	3
2008	1	1	2
2009	2	1	3
2010	1	0	1
2011	2	2	4
2012	1	0	1
2014	2	1	3
2015	3	0	3
2016	1	0	1
2017	3	0	3
2018	2	0	2
2019	5	1	6
2020	2	1	3
2021	0	1	1
2022	0	2	2
2024	1	2	3

Below are the most recent publications written about "Amyloid" by people in Profiles.

Lam AD, Thibault EG, Mayblyum DV, Hsieh S, Pellerin KR, Sternberg EJ, Viswanathan A, Buss S, Sarkis RA, Jacobs HIL, Johnson KA, Sperling RA. Association of Seizure Foci and Location of Tau and Amyloid Deposition and Brain Atrophy in Patients With Alzheimer Disease and Seizures. Neurology. 2024 Nov 12; 103(9):e209920.

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Wang J, Lin Q, Qiu C, McClements DJ, Ji H, Jin Z. Composite biopolymer foams fabricated from natural aldehyde functionalized chitosan-whey protein amyloid fibrils: Application for removal of phthalate esters from water. Carbohydr Polym. 2025 Jan 15; 348(Pt A):122789.

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Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2632-2652.

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Prokaeva T, Klimtchuk ES, Feschenko P, Spencer B, Cui H, Burks EJ, Aslebagh R, Muneeruddin K, Shaffer SA, Varghese E, Berk JL, Connors LH. An additive destabilising effect of compound T60I and V122I substitutions in ATTRv amyloidosis. Amyloid. 2023 Jun; 30(2):141-152.

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Nicastro LK, de Anda J, Jain N, Grando KCM, Miller AL, Bessho S, Gallucci S, Wong GCL, T?kel ?. Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses. PLoS Pathog. 2022 08; 18(8):e1010742.

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Janssen O, Jansen WJ, Vos SJB, Boada M, Parnetti L, Gabryelewicz T, Fladby T, Molinuevo JL, Villeneuve S, Hort J, Epelbaum S, Lle? A, Engelborghs S, van der Flier WM, Landau S, Popp J, Wallin A, Scheltens P, Rikkert MO, Snyder PJ, Rowe C, Ch?telat G, Ru?z A, Marqui? M, Chipi E, Wolfsgruber S, Heneka M, Boecker H, Peters O, Jarholm J, Rami L, Tort-Merino A, Binette AP, Poirier J, Rosa-Neto P, Cerman J, Dubois B, Teichmann M, Alcolea D, Fortea J, S?nchez-Saudin?s MB, Ebenau J, Pocnet C, Eckerstr?m M, Thompson L, Villemagne V, Buckley R, Burnham S, Delarue M, Freund-Levi Y, Wallin ?K, Ramakers I, Tsolaki M, Soininen H, Hampel H, Spiru L, Tijms B, Ossenkoppele R, Verhey FRJ, Jessen F, Visser PJ. Characteristics of subjective cognitive decline associated with amyloid positivity. Alzheimers Dement. 2022 10; 18(10):1832-1845.

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Tursi SA, Puligedda RD, Szabo P, Nicastro LK, Miller AL, Qiu C, Gallucci S, Relkin NR, Buttaro BA, Dessain SK, T?kel ?. Salmonella Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli. Nat Commun. 2020 02 21; 11(1):1007.

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Luciunaite A, McManus RM, Jankunec M, R?cz I, Dansokho C, Dalgediene I, Schwartz S, Brosseron F, Heneka MT. Soluble A? oligomers and protofibrils induce NLRP3 inflammasome activation in microglia. J Neurochem. 2020 12; 155(6):650-661.

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Brosseron F, Kolbe CC, Santarelli F, Carvalho S, Antonell A, Castro-Gomez S, Tacik P, Namasivayam AA, Mangone G, Schneider R, Latz E, W?llner U, Svenningsson P, S?nchez-Valle R, Molinuevo JL, Corvol JC, Heneka MT. Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. Alzheimers Dement. 2020 02; 16(2):292-304.

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Aftabizadeh M, Tatarek-Nossol M, Andreetto E, El Bounkari O, Kipp M, Beyer C, Latz E, Bernhagen J, Kapurniotu A. Blocking Inflammasome Activation Caused by ?-Amyloid Peptide (A?) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic. ACS Chem Neurosci. 2019 08 21; 10(8):3703-3717.

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