"Dynactin Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-subunit protein of EUKARYOTIC CELLS. It functions in bidirectional intracellular transport of ORGANELLES and CYTOPLASMIC VESICLES by linking them to DYNEIN and KINESIN.
| Descriptor ID |
D000072159
|
| MeSH Number(s) |
D05.500.142 D12.776.220.600.450.150 D12.776.631.560.225
|
| Concept/Terms |
Dynactin Subunit 2- Dynactin Subunit 2
- Dynamitin Protein
- p50 Dynamitin
- Dynamitin, p50
- Dynactin-2
- Dynactin 2
Dynactin Subunit 1- Dynactin Subunit 1
- Dynein Activator Protein
- p150(Glued)
- 150 kDa Dynein-Associated Protein
- 150 kDa Dynein Associated Protein
- Dynein-Associated Protein, 150-kDa
- 150-kDa Dynein-Associated Protein
- Dynein Associated Protein, 150 kDa
- Dynactin
- Dynactin 1
|
Below are MeSH descriptors whose meaning is more general than "Dynactin Complex".
Below are MeSH descriptors whose meaning is more specific than "Dynactin Complex".
This graph shows the total number of publications written about "Dynactin Complex" by people in this website by year, and whether "Dynactin Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dynactin Complex" by people in Profiles.
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Collins ES, Balchand SK, Faraci JL, Wadsworth P, Lee WL. Cell cycle-regulated cortical dynein/dynactin promotes symmetric cell division by differential pole motion in anaphase. Mol Biol Cell. 2012 Sep; 23(17):3380-90.
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Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P. Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux. Mol Biol Cell. 2010 Mar 15; 21(6):979-88.
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Str?m AL, Shi P, Zhang F, Gal J, Kilty R, Hayward LJ, Zhu H. Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation. J Biol Chem. 2008 Aug 15; 283(33):22795-805.
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Uetake Y, Terada Y, Matuliene J, Kuriyama R. Interaction of Cep135 with a p50 dynactin subunit in mammalian centrosomes. Cell Motil Cytoskeleton. 2004 May; 58(1):53-66.
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Puls I, Jonnakuty C, LaMonte BH, Holzbaur EL, Tokito M, Mann E, Floeter MK, Bidus K, Drayna D, Oh SJ, Brown RH, Ludlow CL, Fischbeck KH. Mutant dynactin in motor neuron disease. Nat Genet. 2003 Apr; 33(4):455-6.
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Rusan NM, Tulu US, Fagerstrom C, Wadsworth P. Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport. J Cell Biol. 2002 Sep 16; 158(6):997-1003.
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Vaughan PS, Leszyk JD, Vaughan KT. Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactin. J Biol Chem. 2001 Jul 13; 276(28):26171-9.
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Purohit A, Pihan GA, Doxsey SJ. Methods for the study of pericentrin in centrosome assembly and function. Methods Cell Biol. 2001; 67:53-69.
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Young A, Dictenberg JB, Purohit A, Tuft R, Doxsey SJ. Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes. Mol Biol Cell. 2000 Jun; 11(6):2047-56.
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Purohit A, Tynan SH, Vallee R, Doxsey SJ. Direct interaction of pericentrin with cytoplasmic dynein light intermediate chain contributes to mitotic spindle organization. J Cell Biol. 1999 Nov 01; 147(3):481-92.