Endosomal Sorting Complexes Required for Transport

"Endosomal Sorting Complexes Required for Transport" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.

Descriptor ID	D056827
MeSH Number(s)	D05.500.199 D12.776.543.990.493
Concept/Terms	Endosomal Sorting Complexes Required for Transport Endosomal Sorting Complexes Required for Transport ESCRT Machinery Machinery, ESCRT ESCRT Complexes Complexes, ESCRT Endosomal Sorting Complex Required for Transport Endosomal Sorting Complex Required for Transport Machinery Endosomal Sorting Complex Required for Transport III Endosomal Sorting Complex Required for Transport III ESCRT III Endosomal Sorting Complex Required for Transport I Endosomal Sorting Complex Required for Transport I ESCRT I Endosomal Sorting Complex Required for Transport II Endosomal Sorting Complex Required for Transport II ESCRT II

Below are MeSH descriptors whose meaning is more general than "Endosomal Sorting Complexes Required for Transport".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Endosomal Sorting Complexes Required for Transport [D05.500.199]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Vesicular Transport Proteins [D12.776.543.990]
Endosomal Sorting Complexes Required for Transport [D12.776.543.990.493]

Below are MeSH descriptors whose meaning is related to "Endosomal Sorting Complexes Required for Transport".

Below are MeSH descriptors whose meaning is more specific than "Endosomal Sorting Complexes Required for Transport".

Endosomal Sorting Complexes Required for Transport
Nedd4 Ubiquitin Protein Ligases

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endosomal Sorting Complexes Required for Transport" by people in this website by year, and whether "Endosomal Sorting Complexes Required for Transport" was a major or minor topic of these publications.

Bar chart showing 52 publications over 21 distinct years, with a maximum of 8 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2002	0	1	1
2003	0	1	1
2006	0	5	5
2007	0	2	2
2008	0	3	3
2009	1	7	8
2010	2	0	2
2011	3	0	3
2012	3	1	4
2013	3	1	4
2014	1	0	1
2015	1	1	2
2017	1	0	1
2018	0	1	1
2019	2	1	3
2021	1	1	2
2022	1	1	2
2023	0	1	1
2025	1	1	2
2026	1	2	3

Below are the most recent publications written about "Endosomal Sorting Complexes Required for Transport" by people in Profiles.

Paes T, Zhang Q, Borges CO, Mohan DR, Vaz V, Soares BS, Carroll RS, Kaiser UB, Smith TR, Bi WL, Meredith D, Lerario AM, Abreu AP. Distinct genetic alterations drive Cushing disease vs silent corticotroph adenomas. J Clin Endocrinol Metab. 2026 Oct 16; 111(11):3062-3074.

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Jun YW, Hass EP, Lee S, Fazzio TG, Gao FB. Mislocalization of FTD3-associated mutant CHMP2B to the nucleus of human neurons due to loss of a nuclear export signal. Acta Neuropathol Commun. 2026 01 20; 14(1):45.

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Chaugule S, Yang YS, Sato T, Mayer E, Shim JH. USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development. Cell Mol Life Sci. 2026 Jan 15; 83(1):72.

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Zhang F, Wang Y, Zhang L, Wang C, Chen D, Liu H, Xu R, Haynes CM, Shim JH, Ge X. The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence. Elife. 2025 Jul 07; 13.

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Mohan DR, Paes T, Buelvas Mebarak J, Meredith DM, Soares B, Vaz V, Carroll RS, Kaiser UB, Smith TR, Bi WL, Lerario AM, Abreu AP. Non-recurrent mutations and copy number changes predominate pituitary adenoma genomes. Eur J Endocrinol. 2025 Apr 30; 192(5):590-602.

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Jun YW, Lee S, Ban BK, Lee JA, Gao FB. Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis. Autophagy. 2023 07; 19(7):2045-2061.

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Chen Y, Krishnan G, Parsi S, Pons M, Nikolaki V, Cao L, Xu Z, Gao FB. The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias. Acta Neuropathol Commun. 2022 11 22; 10(1):169.

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Wang R, Miao G, Shen JL, Fortier TM, Baehrecke EH. ESCRT dysfunction compromises endoplasmic reticulum maturation and autophagosome biogenesis in Drosophila. Curr Biol. 2022 03 28; 32(6):1262-1274.e4.

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Massart J, Sjögren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barrès R, O'Gorman DJ, Zierath JR, Krook A. Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. Nat Commun. 2021 10 12; 12(1):5948.

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Chaugule S, Kim JM, Yang YS, Knobeloch KP, He X, Shim JH. Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. Int J Mol Sci. 2021 Sep 24; 22(19).

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