Transcription Factors

"Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.

Descriptor ID	D014157
MeSH Number(s)	D12.776.930
Concept/Terms	Transcription Factors Transcription Factors Factors, Transcription Transcription Factor Factor, Transcription

Below are MeSH descriptors whose meaning is more general than "Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]

Below are MeSH descriptors whose meaning is related to "Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "Transcription Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transcription Factors" by people in this website by year, and whether "Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 1118 publications over 31 distinct years, with a maximum of 80 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	15	2	17
1996	10	6	16
1997	11	5	16
1998	11	9	20
1999	17	13	30
2000	19	11	30
2001	23	9	32
2002	53	22	75
2003	39	21	60
2004	52	28	80
2005	36	18	54
2006	28	17	45
2007	20	15	35
2008	22	20	42
2009	21	31	52
2010	30	22	52
2011	26	20	46
2012	28	27	55
2013	21	23	44
2014	24	25	49
2015	22	22	44
2016	16	21	37
2017	14	10	24
2018	19	16	35
2019	16	10	26
2020	11	15	26
2021	12	9	21
2022	6	16	22
2023	4	11	15
2024	5	9	14
2025	4	0	4

Below are the most recent publications written about "Transcription Factors" by people in Profiles.

Guharajan S, Parisutham V, Brewster RC. A systematic survey of TF function in E. coli suggests RNAP stabilization is a prevalent strategy for both repressors and activators. Nucleic Acids Res. 2025 Feb 08; 53(4).

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Guharajan S, Parisutham V, Brewster RC. A systematic survey of TF function in E. coli suggests RNAP stabilization is a prevalent strategy for both repressors and activators. Nucleic Acids Res. 2025 Feb 08; 53(4).

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Gritti I, Wan J, Weeresekara V, Vaz JM, Tarantino G, Bryde TH, Vijay V, Kammula AV, Kattel P, Zhu S, Vu P, Chan M, Wu MJ, Gordan JD, Patra KC, Silveira VS, Manguso RT, Wein MN, Ott CJ, Qi J, Liu D, Sakamoto K, Gujral TS, Bardeesy N. DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming. Cancer Discov. 2025 Feb 07; 15(2):382-400.

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Pierson Smela M, Kramme CC, Fortuna PRJ, Wolf B, Goel S, Adams J, Ma C, Velychko S, Widocki U, Srikar Kavirayuni V, Chen T, Vincoff S, Dong E, Kohman RE, Kobayashi M, Shioda T, Church GM, Chatterjee P. Rapid human oogonia-like cell specification via transcription factor-directed differentiation. EMBO Rep. 2025 Feb; 26(4):1114-1143.

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Rahman S, Bloye G, Farah N, Demeulemeester J, Costa JR, O'Connor D, Pocock R, Rapoz-D'Silva T, Turna A, Wang L, Lee S, Fielding AK, Roels J, Jaksik R, Dawidowska M, Van Vlierberghe P, Hadjur S, Hughes JR, Davies JOJ, Gutierrez A, Kelliher MA, Van Loo P, Dawson MA, Mansour MR. Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia. Blood. 2024 Nov 28; 144(22):2319-2326.

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Kim Y, Nguyen TT, Durning DJ, Ishidate T, Aydemir O, Mello CC, Hu Y, Kahn TW, Aroian RV. Resistance to Cry14A family Bacillus thuringiensis crystal proteins in Caenornabditis elegans operates via the nhr-31 transcription factor and vacuolar-type ATPase pathway. PLoS Pathog. 2024 Oct; 20(10):e1012611.

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Fitisemanu FM, Padilla-Benavides T. Emerging perspectives of copper-mediated transcriptional regulation in mammalian cell development. Metallomics. 2024 10 04; 16(10).

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Peterson CL. Heterochromatin: Hiding from the remodeling machines. Mol Cell. 2024 Sep 05; 84(17):3167-3169.

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Flynn MJ, Harper NW, Li R, Zhu LJ, Lee MJ, Benanti JA. Calcineurin promotes adaptation to chronic stress through two distinct mechanisms. Mol Biol Cell. 2024 Oct 01; 35(10):ar123.

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Kim H, Tan TK, Lee DZY, Huang XZ, Ong JZL, Kelliher MA, Yeoh AEJ, Sanda T, Tan SH. Oncogenic dependency on SWI/SNF chromatin remodeling factors in T-cell acute lymphoblastic leukemia. Leukemia. 2024 Sep; 38(9):1906-1917.

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