SMARCB1 Protein

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"SMARCB1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.

Descriptor ID	D000071796
MeSH Number(s)	D12.776.260.716 D12.776.660.235.650 D12.776.664.235.900 D12.776.930.809
Concept/Terms	SMARCB1 Protein SMARCB1 Protein Integrase Interactor 1 Protein BAF47 Protein SNF5 Homolog Protein Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1 Swi Snf Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1 BRG1-Associated Factor 47 Protein BRG1 Associated Factor 47 Protein

Below are MeSH descriptors whose meaning is more general than "SMARCB1 Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
SMARCB1 Protein [D12.776.260.716]
Nuclear Proteins [D12.776.660]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
SMARCB1 Protein [D12.776.660.235.650]
Nucleoproteins [D12.776.664]
Chromosomal Proteins, Non-Histone [D12.776.664.235]
SMARCB1 Protein [D12.776.664.235.900]
Transcription Factors [D12.776.930]
SMARCB1 Protein [D12.776.930.809]

Below are MeSH descriptors whose meaning is related to "SMARCB1 Protein".

Below are MeSH descriptors whose meaning is more specific than "SMARCB1 Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "SMARCB1 Protein" by people in this website by year, and whether "SMARCB1 Protein" was a major or minor topic of these publications.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2003	0	2	2
2004	0	1	1
2005	0	1	1
2006	0	1	1
2010	0	1	1
2019	1	0	1
2021	0	1	1

Below are the most recent publications written about "SMARCB1 Protein" by people in Profiles.

Baker TG, Lyons MJ, Leddy L, Parham DM, Welsh CT. Epithelioid Sarcoma Arising in a Long-Term Survivor of an Atypical Teratoid/Rhabdoid Tumor in a Patient With Rhabdoid Tumor Predisposition Syndrome. Pediatr Dev Pathol. 2021 Mar-Apr; 24(2):164-168.

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Trieu V, Aulet RM, Ciolino A, Rimash T. SMARCB1-Deficient Sinonasal Carcinoma: A Case Report and Discussion of the Clinical Implications. Ann Otol Rhinol Laryngol. 2019 Jul; 128(7):676-680.

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Kuwahara Y, Kennedy LM, Karnezis AN, Mora-Blanco EL, Rogers AB, Fletcher CD, Huntsman DG, Roberts CWM, Rathmell WK, Weissman BE. High Frequency of Ovarian Cyst Development in Vhl2B/+;Snf5+/- Mice. Am J Pathol. 2018 07; 188(7):1510-1516.

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Kuwahara Y, Mora-Blanco EL, Banine F, Rogers AB, Fletcher C, Sherman LS, Roberts CW, Weissman BE. Establishment and characterization of MRT cell lines from genetically engineered mouse models and the influence of genetic background on their development. Int J Cancer. 2013 Jun 15; 132(12):2767-77.

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Bakshi R, Hassan MQ, Pratap J, Lian JB, Montecino MA, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS. The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes. J Cell Physiol. 2010 Nov; 225(2):569-76.

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Guidi CJ, Mudhasani R, Hoover K, Koff A, Leav I, Imbalzano AN, Jones SN. Functional interaction of the retinoblastoma and Ini1/Snf5 tumor suppressors in cell growth and pituitary tumorigenesis. Cancer Res. 2006 Aug 15; 66(16):8076-82.

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Imbalzano AN, Jones SN. Snf5 tumor suppressor couples chromatin remodeling, checkpoint control, and chromosomal stability. Cancer Cell. 2005 Apr; 7(4):294-5.

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Doan DN, Veal TM, Yan Z, Wang W, Jones SN, Imbalzano AN. Loss of the INI1 tumor suppressor does not impair the expression of multiple BRG1-dependent genes or the assembly of SWI/SNF enzymes. Oncogene. 2004 Apr 22; 23(19):3462-73.

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Guidi CJ, Veal TM, Jones SN, Imbalzano AN. Transcriptional compensation for loss of an allele of the Ini1 tumor suppressor. J Biol Chem. 2004 Feb 06; 279(6):4180-5.

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Favre M, Butticaz C, Stevenson B, Jongeneel CV, Telenti A. High frequency of alternative splicing of human genes participating in the HIV-1 life cycle: a model using TSG101, betaTrCP, PPIA, INI1, NAF1, and PML. J Acquir Immune Defic Syndr. 2003 Oct 01; 34(2):127-33.

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