Basic Helix-Loop-Helix Transcription Factors

"Basic Helix-Loop-Helix Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of DNA-binding transcription factors that contain a basic HELIX-LOOP-HELIX MOTIF.

Descriptor ID	D051792
MeSH Number(s)	D12.776.260.103 D12.776.930.125
Concept/Terms	Basic Helix-Loop-Helix Transcription Factors Basic Helix-Loop-Helix Transcription Factors Basic Helix Loop Helix Transcription Factors bHLH Transcription Factors Transcription Factors, bHLH bHLH Proteins

Below are MeSH descriptors whose meaning is more general than "Basic Helix-Loop-Helix Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic Helix-Loop-Helix Transcription Factors [D12.776.260.103]
Transcription Factors [D12.776.930]
Basic Helix-Loop-Helix Transcription Factors [D12.776.930.125]

Below are MeSH descriptors whose meaning is related to "Basic Helix-Loop-Helix Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "Basic Helix-Loop-Helix Transcription Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Basic Helix-Loop-Helix Transcription Factors" by people in this website by year, and whether "Basic Helix-Loop-Helix Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 107 publications over 29 distinct years, with a maximum of 7 publications in 2008 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	0	2	2
1999	0	3	3
2000	0	3	3
2001	0	3	3
2002	0	2	2
2003	0	6	6
2004	0	3	3
2005	1	3	4
2006	2	4	6
2007	2	4	6
2008	1	6	7
2009	2	3	5
2010	2	1	3
2011	1	1	2
2012	3	2	5
2013	5	2	7
2014	3	2	5
2015	2	2	4
2016	3	1	4
2017	1	1	2
2018	1	1	2
2019	1	1	2
2020	2	2	4
2021	5	1	6
2022	0	4	4
2023	0	2	2
2024	0	3	3
2025	1	0	1

Below are the most recent publications written about "Basic Helix-Loop-Helix Transcription Factors" by people in Profiles.

Cheng YF, Kempfle JS, Chiang H, Tani K, Wang Q, Chen SH, Lenz D, Chen WY, Wu W, Petrillo M, Edge ASB. Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation. PLoS Genet. 2025 Jan; 21(1):e1011573.

View in: PubMed
Colino-Lage H, Guerrero-G?mez D, G?mez-Orte E, Gonz?lez X, Martina JA, Dansen TB, Ayuso C, Askjaer P, Puertollano R, Irazoqui JE, Cabello J, Miranda-Vizuete A. Regulation of Caenorhabditis elegans HLH-30 subcellular localization dynamics: Evidence for a redox-dependent mechanism. Free Radic Biol Med. 2024 Oct; 223:369-383.

View in: PubMed
Gonzalez X, Irazoqui JE. Distinct members of the Caenorhabditis elegans CeMbio reference microbiota exert cryptic virulence that is masked by host defense. Mol Microbiol. 2024 09; 122(3):387-402.

View in: PubMed
Hsieh HC, Huang IH, Chang SW, Chen PL, Su YC, Wang S, Tsai WJ, Chen PH, Aroian RV, Chen CS. PRMT-7/PRMT7 activates HLH-30/TFEB to guard plasma membrane integrity compromised by bacterial pore-forming toxins. Autophagy. 2024 06; 20(6):1335-1358.

View in: PubMed
Goswamy D, Gonzalez X, Labed SA, Irazoqui JE. C. elegans orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB. Front Immunol. 2023; 14:1094145.

View in: PubMed
Masoudi N, Schnabel R, Yemini E, Leyva-D?az E, Hobert O. Cell-specific effects of the sole C. elegans Daughterless/E protein homolog, HLH-2, on nervous system development. Development. 2023 01 01; 150(1).

View in: PubMed
Puig S, Shelton MA, Barko K, Seney ML, Logan RW. Sex-specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal and analgesia. Genes Brain Behav. 2022 09; 21(7):e12829.

View in: PubMed
Gamble MC, Chuan B, Gallego-Martin T, Shelton MA, Puig S, O'Donnell CP, Logan RW. A role for the circadian transcription factor NPAS2 in the progressive loss of non-rapid eye movement sleep and increased arousal during fentanyl withdrawal in male mice. Psychopharmacology (Berl). 2022 Oct; 239(10):3185-3200.

View in: PubMed
Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, Thuong NTT, Thwaites GE, Caws M, Thai PVK, Bang ND, Chau TTH, Khor CC, Li Z, Hibberd M, Chang X, Nguyen FK, Hernandez CA, Jones MA, Sassetti CM, Fitzgerald KA, Musvosvi M, Gela A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk. J Immunol. 2022 03 15; 208(6):1352-1361.

View in: PubMed
Becker-Krail DD, Parekh PK, Ketchesin KD, Yamaguchi S, Yoshino J, Hildebrand MA, Dunham B, Ganapathiraju MK, Logan RW, McClung CA. Circadian transcription factor NPAS2 and the NAD+ -dependent deacetylase SIRT1 interact in the mouse nucleus accumbens and regulate reward. Eur J Neurosci. 2022 02; 55(3):675-693.

View in: PubMed

People

Explore

Similar Concepts

Top Journals