Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins.

Descriptor ID	D056926
MeSH Number(s)	D08.811.913.050.134.415.500.049 D12.644.128.100 D12.776.189.200 D12.776.260.103.562 D12.776.930.125.562
Concept/Terms	CLOCK Proteins CLOCK Proteins Circadian Locomotor Output Cycles Kaput Proteins CLOCK Protein

Below are MeSH descriptors whose meaning is more general than "CLOCK Proteins".

Below are MeSH descriptors whose meaning is related to "CLOCK Proteins".

Below are MeSH descriptors whose meaning is more specific than "CLOCK Proteins".