Muscle, Skeletal

"Muscle, Skeletal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

Descriptor ID	D018482
MeSH Number(s)	A02.633.567 A10.690.552.500
Concept/Terms	Muscle, Skeletal Muscle, Skeletal Muscle, Voluntary Muscles, Voluntary Voluntary Muscle Voluntary Muscles Skeletal Muscle Muscles, Skeletal Skeletal Muscles Soleus Muscle Soleus Muscle Muscle, Soleus Plantaris Muscle Plantaris Muscle Muscle, Plantaris Anterior Tibial Muscle Anterior Tibial Muscle Muscle, Anterior Tibial Tibial Muscle, Anterior Gastrocnemius Muscle Gastrocnemius Muscle Muscle, Gastrocnemius

Below are MeSH descriptors whose meaning is more general than "Muscle, Skeletal".

Anatomy [A]
Musculoskeletal System [A02]
Muscles [A02.633]
Muscle, Skeletal [A02.633.567]
Tissues [A10]
Muscles [A10.690]
Muscle, Striated [A10.690.552]
Muscle, Skeletal [A10.690.552.500]

Below are MeSH descriptors whose meaning is related to "Muscle, Skeletal".

Below are MeSH descriptors whose meaning is more specific than "Muscle, Skeletal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Muscle, Skeletal" by people in this website by year, and whether "Muscle, Skeletal" was a major or minor topic of these publications.

Bar chart showing 657 publications over 31 distinct years, with a maximum of 36 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	5	6	11
1996	5	3	8
1997	2	4	6
1998	3	9	12
1999	4	11	15
2000	5	5	10
2001	7	5	12
2002	20	7	27
2003	26	10	36
2004	25	8	33
2005	24	9	33
2006	21	13	34
2007	19	7	26
2008	25	9	34
2009	19	9	28
2010	10	12	22
2011	20	6	26
2012	20	9	29
2013	18	7	25
2014	20	6	26
2015	7	10	17
2016	15	2	17
2017	18	11	29
2018	15	10	25
2019	11	4	15
2020	7	11	18
2021	8	10	18
2022	2	18	20
2023	1	10	11
2024	13	6	19
2025	11	4	15

Below are the most recent publications written about "Muscle, Skeletal" by people in Profiles.

Hayden CMT, Busa MA, Smith ZH, Nagarajan R, Arieta LR, Kent JA. Skeletal muscle energetics during submaximal contractions are linked to metabolic performance during ambulatory exercise: A pilot study in male adults. Physiol Rep. 2025 Aug; 13(16):e70528.

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Sen I, Smith JAB, Caria E, Orlov I, Savikj M, Brady AJ, Lian K, Ellefsen S, Zierath JR, Krook A. Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis. Sci Adv. 2025 Jul 11; 11(28):eads4371.

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Salsi V, Losi F, Fosso B, Ferrarini M, Pini S, Manfredi M, Vattemi G, Mongini T, Maggi L, Pesole G, Henras AK, Kaufman PD, McStay B, Tupler R. Nucleolar FRG2 lncRNAs inhibit rRNA transcription and cytoplasmic translation, linking FSHD to dysregulation of muscle-specific protein synthesis. Nucleic Acids Res. 2025 Jul 08; 53(13).

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Ehrlich AM, MacGregor KA, Ashcroft SP, Small L, Altintas A, Chibalin AV, Anagho-Mattanovich M, Stocks B, Moritz T, Treebak JT, Zierath JR. HIF1a mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise. Proc Natl Acad Sci U S A. 2025 Jul 15; 122(28):e2504080122.

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Gromova A, Cha B, Nguyen N, Garg D, Coscolluela C, Strickland LM, Luong D, Longo F, Sopher BL, ElMallah MK, La Spada AR. Neuromuscular junction transcriptome analysis of spinal and bulbar muscular atrophy mice implicates sarcomere gene expression and calcium flux dysregulation in disease pathogenesis. Hum Mol Genet. 2025 Jul 03; 34(14):1238-1251.

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Smith JAB, Gabriel BM, Brady AJ, Abdelmoez AM, Savikj M, Wright SC, Koutsilieri S, Barr?s R, Lauschke VM, Krook A, Zierath JR, Pillon NJ. Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: Insights from in vitro analysis. Mol Metab. 2025 Sep; 99:102200.

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Kj?rgaard J, Lindqvist CB, Quesada JP, Jessen S, Schlabs F, Ehrlich AM, Yonamine CY, Garc?a-Ure?a M, Schmalbruch JH, Small L, Thomassen M, Lemminger AK, Eibye K, Gonzalez-Franquesa A, Stidsen JV, H?jlund K, Zierath JR, Kilpel?inen TO, Bangsbo J, Treebak JT, Hostrup M, Deshmukh AS. Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake. Cell Rep Med. 2025 Jun 17; 6(6):102163.

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Hendry JI, Erol ME, Layec G, Debold EP, Tewari SG, Wallqvist A, Pannala VR. A human skeletal muscle cross-bridge model to characterize the role of metabolite accumulation in muscle fatigue. Exp Physiol. 2025 Sep; 110(9):1283-1301.

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Kj?rgaard J, Stocks B, Henderson J, Freemantle JB, Rizo-Roca D, Puglia M, Madrazo Montoya M, Andersson D, B?ckdahl J, Eriksson-Hogling D, Stidsen JV, Wierer M, Rasmussen S, Sakamoto K, H?jlund K, Ryd?n M, Zierath JR, Krook A, Deshmukh AS. Personalized molecular signatures of insulin resistance and type 2 diabetes. Cell. 2025 Jul 24; 188(15):4106-4122.e16.

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Pinto-Hernandez P, Fernandez-Sanjurjo M, Paget D, Caravia XM, Roiz-Valle D, Castilla-Silgado J, Diez-Robles S, Coto-Vilcapoma A, Fernandez-Vivero D, Gama-Perez P, Garcia-Roves PM, Lopez-Otin C, Zierath JR, Krook A, Fernandez-Garcia B, Tomas-Zapico C, Iglesias-Gutierrez E. Training-induced plasma miR-29a-3p is secreted by skeletal muscle and contributes to metabolic adaptations to resistance exercise in mice. Mol Metab. 2025 Aug; 98:102173.

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