Muscle Fibers, Skeletal

"Muscle Fibers, Skeletal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Large, multinucleate single cells, either cylindrical or prismatic in shape, that form the basic unit of SKELETAL MUSCLE. They consist of MYOFIBRILS enclosed within and attached to the SARCOLEMMA. They are derived from the fusion of skeletal myoblasts (MYOBLASTS, SKELETAL) into a syncytium, followed by differentiation.

Descriptor ID	D018485
MeSH Number(s)	A10.690.552.500.500 A11.620.249
Concept/Terms	Muscle Fibers, Skeletal Muscle Fibers, Skeletal Fiber, Skeletal Muscle Fibers, Skeletal Muscle Muscle Fiber, Skeletal Skeletal Muscle Fiber Skeletal Myocytes Skeletal Muscle Fibers Myocytes, Skeletal Myocyte, Skeletal Skeletal Myocyte Myotubes Myotube

Below are MeSH descriptors whose meaning is more general than "Muscle Fibers, Skeletal".

Anatomy [A]
Tissues [A10]
Muscles [A10.690]
Muscle, Striated [A10.690.552]
Muscle, Skeletal [A10.690.552.500]
Muscle Fibers, Skeletal [A10.690.552.500.500]
Cells [A11]
Muscle Cells [A11.620]
Muscle Fibers, Skeletal [A11.620.249]

Below are MeSH descriptors whose meaning is related to "Muscle Fibers, Skeletal".

Below are MeSH descriptors whose meaning is more specific than "Muscle Fibers, Skeletal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Muscle Fibers, Skeletal" by people in this website by year, and whether "Muscle Fibers, Skeletal" was a major or minor topic of these publications.

Bar chart showing 81 publications over 27 distinct years, with a maximum of 10 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	1	0	1
2001	0	1	1
2002	2	1	3
2003	0	1	1
2004	3	3	6
2005	3	1	4
2006	1	1	2
2007	1	2	3
2008	1	2	3
2009	2	2	4
2010	1	1	2
2011	0	1	1
2012	5	5	10
2013	2	0	2
2014	2	1	3
2015	1	0	1
2016	1	2	3
2017	2	0	2
2018	2	2	4
2019	4	3	7
2020	2	0	2
2021	2	1	3
2022	0	4	4
2023	0	1	1
2024	1	4	5
2025	0	2	2

Below are the most recent publications written about "Muscle Fibers, Skeletal" by people in Profiles.

Foster AD, Straight CR, Woods PC, Lee C, Kent JA, Chipkin SR, Debold EP, Miller MS. Cellular and molecular contractile function in aged human skeletal muscle is altered by phosphate and acidosis and partially reversed with an ATP analog. Am J Physiol Cell Physiol. 2025 Apr 01; 328(4):C1220-C1233.

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Stocks B, Quesada JP, Mozzicato AM, Jacob C, Jensen S, MacGregor KA, Bangsbo J, Zierath JR, Hostrup M, Deshmukh AS. Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise. Sci Adv. 2025 Jan 31; 11(5):eadp8608.

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Katayama M, Nomura K, Mudry JM, Chibalin AV, Krook A, Zierath JR. Exercise-induced methylation of the Serhl2 promoter and implication for lipid metabolism in rat skeletal muscle. Mol Metab. 2025 Feb; 92:102081.

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Mart?nez P, Silva M, Abarz?a S, Tevy MF, Jaimovich E, Constantine-Paton M, Bustos FJ, van Zundert B. Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death. Mol Med. 2024 Oct 25; 30(1):185.

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Debold EP, Westerblad H. New insights into the cellular and molecular mechanisms of skeletal muscle fatigue: the Marion J. Siegman Award Lectureships. Am J Physiol Cell Physiol. 2024 Oct 01; 327(4):C946-C958.

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Liu S, Marang C, Woodward M, Joumaa V, Leonard T, Scott B, Debold E, Herzog W, Walcott S. Modeling thick filament activation suggests a molecular basis for force depression. Biophys J. 2024 03 05; 123(5):555-571.

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Guay KP, Ke H, Gierasch LM, Gershenson A, Hebert DN. Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types. Methods Mol Biol. 2024; 2750:143-163.

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Fontelonga T, Hall AJ, Brown JL, Jung YL, Alexander MS, Dominov JA, Mouly V, Vieira N, Zatz M, Vainzof M, Gussoni E. Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin. Adv Biol (Weinh). 2023 12; 7(12):e2300157.

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Pillon NJ, Sard?n Puig L, Altintas A, Kamble PG, Casan?-Gald?n S, Gabriel BM, Barr?s R, Conesa A, Chibalin AV, N?slund E, Krook A, Zierath JR. Palmitate impairs circadian transcriptomics in muscle cells through histone modification of enhancers. Life Sci Alliance. 2023 01; 6(1).

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Ke H, Guay KP, Flotte TR, Gierasch LM, Gershenson A, Hebert DN. Secretion of functional a1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2206103119.

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