AMP-Activated Protein Kinases

"AMP-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.

Descriptor ID	D055372
MeSH Number(s)	D08.811.913.696.620.682.700.085 D12.644.360.062 D12.776.476.062
Concept/Terms	AMP-Activated Protein Kinases AMP-Activated Protein Kinases AMP Activated Protein Kinases AMP-Activated Kinase AMP Activated Kinase AMP-Activated Protein Kinase AMP Activated Protein Kinase 5'-AMP-Activated Protein Kinase 5' AMP Activated Protein Kinase AMP-Activated Protein Kinase beta Subunits AMP-Activated Protein Kinase beta Subunits AMP Activated Protein Kinase beta Subunits AMP-Activated Protein Kinase beta Subunit AMP Activated Protein Kinase beta Subunit AMP-Activated Protein Kinase gamma Subunits AMP-Activated Protein Kinase gamma Subunits AMP Activated Protein Kinase gamma Subunits AMP-Activated Protein Kinase gamma Subunit AMP Activated Protein Kinase gamma Subunit AMP-Activated Protein Kinase alpha Subunits AMP-Activated Protein Kinase alpha Subunits AMP Activated Protein Kinase alpha Subunits PRKAA AMP-Activated Protein Kinase alpha Subunit AMP Activated Protein Kinase alpha Subunit

Below are MeSH descriptors whose meaning is more general than "AMP-Activated Protein Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
AMP-Activated Protein Kinases [D08.811.913.696.620.682.700.085]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
AMP-Activated Protein Kinases [D12.644.360.062]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
AMP-Activated Protein Kinases [D12.776.476.062]

Below are MeSH descriptors whose meaning is related to "AMP-Activated Protein Kinases".

Below are MeSH descriptors whose meaning is more specific than "AMP-Activated Protein Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "AMP-Activated Protein Kinases" by people in this website by year, and whether "AMP-Activated Protein Kinases" was a major or minor topic of these publications.

Bar chart showing 61 publications over 22 distinct years, with a maximum of 6 publications in 2008 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2004	0	2	2
2005	0	4	4
2006	0	1	1
2007	0	1	1
2008	3	3	6
2009	5	1	6
2010	2	3	5
2011	1	1	2
2012	3	0	3
2013	0	5	5
2014	2	1	3
2015	2	3	5
2016	3	0	3
2017	1	2	3
2018	3	0	3
2020	0	2	2
2021	2	0	2
2022	0	1	1
2023	1	0	1
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "AMP-Activated Protein Kinases" by people in Profiles.

Ke L, He W, Zong C, Wang T, Xiao J, Cao Y, Xiao H, Liu X. A novel peptide derived from Haematococcus pluvialis residue balanced lipid metabolism through NHR-49/PPARa and AAK-2/AMPK pathways in Caenorhabditis elegans. Biofactors. 2025 Mar-Apr; 51(2):e70017.

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Swift NA, Yang Q, Jester HM, Zhou X, Manuel A, Kemp BE, Steinberg GR, Ma T. Suppression of neuronal AMPK?2 isoform impairs recognition memory and synaptic plasticity. Neurobiol Dis. 2024 Oct 15; 201:106664.

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Shuai X, Dai T, McClements DJ, Ruan R, Du L, Liu Y, Chen J. Hypolipidemic effects of macadamia oil are related to AMPK activation and oxidative stress relief: In vitro and in vivo studies. Food Res Int. 2023 06; 168:112772.

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Ju S, Chen H, Wang S, Lin J, Ma Y, Aroian RV, Peng D, Sun M. C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens. Commun Biol. 2022 06 30; 5(1):643.

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Ahuja P, Ng CF, Pang BPS, Chan WS, Tse MCL, Bi X, Kwan HR, Brobst D, Herlea-Pana O, Yang X, Du G, Saengnipanthkul S, Noh HL, Jiao B, Kim JK, Lee CW, Ye K, Chan CB. Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice. Autophagy. 2022 06; 18(6):1367-1384.

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Banskota S, Wang H, Kwon YH, Gautam J, Gurung P, Haq S, Hassan FMN, Bowdish DM, Kim JA, Carling D, Fullerton MD, Steinberg GR, Khan WI. Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK. Inflamm Bowel Dis. 2021 05 17; 27(6):914-926.

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Bae-Gartz I, Kasper P, Gro?mann N, Breuer S, Janoschek R, Kretschmer T, Appel S, Schmitz L, Vohlen C, Quaas A, Schweiger MR, Grimm C, Fischer A, Ferrari N, Graf C, Frese CK, Lang S, Demir M, Schramm C, Fink G, Goeser T, D?tsch J, Hucklenbruch-Rother E. Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming. Sci Rep. 2020 09 22; 10(1):15424.

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Maron BJ, Maron MS. PRKAG2 Glycogen Storage Disease Cardiomyopathy: Out of the Darkness and Into the Light. J Am Coll Cardiol. 2020 07 14; 76(2):198-200.

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Kr?ller-Sch?n S, Jansen T, Tran TLP, Kvandov? M, Kalinovic S, Oelze M, Keaney JF, Foretz M, Viollet B, Daiber A, Kossmann S, Lagrange J, Frenis K, Wenzel P, M?nzel T, Schulz E. Endothelial a1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction. Basic Res Cardiol. 2019 01 14; 114(2):8.

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Jansen T, Kr?ller-Sch?n S, Sch?nfelder T, Foretz M, Viollet B, Daiber A, Oelze M, Brandt M, Steven S, Kvandov? M, Kalinovic S, Lagrange J, Keaney JF, M?nzel T, Wenzel P, Schulz E. a1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction. Cardiovasc Res. 2018 12 01; 114(14):1883-1893.

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