Dual-Specificity Phosphatases

"Dual-Specificity Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.

Descriptor ID	D054637
MeSH Number(s)	D08.811.277.352.650.625.225 D08.811.277.352.650.775.250 D08.811.641.755 D12.644.360.268 D12.776.476.268
Concept/Terms	Dual-Specificity Phosphatases Dual-Specificity Phosphatases Dual Specificity Phosphatases Phosphatases, Dual-Specificity Dual-Specificity Phosphatase Dual Specificity Phosphatase Phosphatase, Dual-Specificity DUSP Phosphatases Phosphatases, DUSP

Below are MeSH descriptors whose meaning is more general than "Dual-Specificity Phosphatases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Phosphoric Monoester Hydrolases [D08.811.277.352.650]
Phosphoprotein Phosphatases [D08.811.277.352.650.625]
Dual-Specificity Phosphatases [D08.811.277.352.650.625.225]
Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
Dual-Specificity Phosphatases [D08.811.277.352.650.775.250]
Multifunctional Enzymes [D08.811.641]
Dual-Specificity Phosphatases [D08.811.641.755]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Dual-Specificity Phosphatases [D12.644.360.268]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Dual-Specificity Phosphatases [D12.776.476.268]

Below are MeSH descriptors whose meaning is related to "Dual-Specificity Phosphatases".

Below are MeSH descriptors whose meaning is more specific than "Dual-Specificity Phosphatases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dual-Specificity Phosphatases" by people in this website by year, and whether "Dual-Specificity Phosphatases" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2003 and 2004 and 2007 and 2009 and 2012 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2004	0	1	1
2007	0	1	1
2009	1	0	1
2012	1	0	1
2014	1	0	1

Below are the most recent publications written about "Dual-Specificity Phosphatases" by people in Profiles.

Gupta R, Bugide S, Wang B, Green MR, Johnson DB, Wajapeyee N. Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway. Proc Natl Acad Sci U S A. 2019 03 05; 116(10):4583-4591.

View in: PubMed
Li H, Jiang X, Yu Y, Huang W, Xing H, Agar NY, Yang HW, Yang B, Carroll RS, Johnson MD. KAP regulates ROCK2 and Cdk2 in an RNA-activated glioblastoma invasion pathway. Oncogene. 2015 Mar 12; 34(11):1432-41.

View in: PubMed
Barreiro LB, Tailleux L, Pai AA, Gicquel B, Marioni JC, Gilad Y. Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1204-9.

View in: PubMed
Zaidi SK, Dowdy CR, van Wijnen AJ, Lian JB, Raza A, Stein JL, Croce CM, Stein GS. Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network. Cancer Res. 2009 Nov 01; 69(21):8249-55.

View in: PubMed
Yu Y, Jiang X, Schoch BS, Carroll RS, Black PM, Johnson MD. Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma. Cancer Res. 2007 Jan 01; 67(1):130-8.

View in: PubMed
Zhang Y, Blattman JN, Kennedy NJ, Duong J, Nguyen T, Wang Y, Davis RJ, Greenberg PD, Flavell RA, Dong C. Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Nature. 2004 Aug 12; 430(7001):793-7.

View in: PubMed
Li G, Gustafson-Brown C, Hanks SK, Nason K, Arbeit JM, Pogliano K, Wisdom RM, Johnson RS. c-Jun is essential for organization of the epidermal leading edge. Dev Cell. 2003 Jun; 4(6):865-77.

View in: PubMed

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