Protein Tyrosine Phosphatases
"Protein Tyrosine Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Descriptor ID |
D017027
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MeSH Number(s) |
D08.811.277.352.650.775
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Concept/Terms |
Protein Tyrosine Phosphatases- Protein Tyrosine Phosphatases
- Phosphatases, Protein Tyrosine
- Tyrosine Phosphatases, Protein
- Phosphotyrosyl Protein Phosphatase
- Phosphatase, Phosphotyrosyl Protein
- Protein Phosphatase, Phosphotyrosyl
- Protein-Tyrosine Phosphatase
- Phosphatase, Protein-Tyrosine
- PTPase
- Tyrosyl Phosphoprotein Phosphatase
- Phosphatase, Tyrosyl Phosphoprotein
- Phosphoprotein Phosphatase, Tyrosyl
- Phosphotyrosine Phosphatase
- Phosphatase, Phosphotyrosine
- Protein-Tyrosine-Phosphatase
- Protein Tyrosine Phosphatase
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Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatases".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatases" by people in this website by year, and whether "Protein Tyrosine Phosphatases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 8 | 1 | 9 |
1998 | 2 | 1 | 3 |
1999 | 1 | 0 | 1 |
2000 | 1 | 0 | 1 |
2001 | 4 | 1 | 5 |
2002 | 2 | 1 | 3 |
2003 | 2 | 0 | 2 |
2004 | 5 | 1 | 6 |
2005 | 3 | 0 | 3 |
2006 | 4 | 1 | 5 |
2007 | 2 | 3 | 5 |
2008 | 2 | 0 | 2 |
2009 | 0 | 2 | 2 |
2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatases" by people in Profiles.
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Logan MA, Hackett R, Doherty J, Sheehan A, Speese SD, Freeman MR. Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury. Nat Neurosci. 2012 Mar 18; 15(5):722-30.
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Choi SH, McCollum D. A role for metaphase spindle elongation forces in correction of merotelic kinetochore attachments. Curr Biol. 2012 Feb 07; 22(3):225-30.
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Rached MT, Kode A, Silva BC, Jung DY, Gray S, Ong H, Paik JH, DePinho RA, Kim JK, Karsenty G, Kousteni S. FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice. J Clin Invest. 2010 Jan; 120(1):357-68.
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Chen K, Craige SE, Keaney JF. Downstream targets and intracellular compartmentalization in Nox signaling. Antioxid Redox Signal. 2009 Oct; 11(10):2467-80.
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Choi SH, P?li-Gulli MP, Mcleod I, Sarkeshik A, Yates JR, Simanis V, McCollum D. Phosphorylation state defines discrete roles for monopolin in chromosome attachment and spindle elongation. Curr Biol. 2009 Jun 23; 19(12):985-95.
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Chen CT, Feoktistova A, Chen JS, Shim YS, Clifford DM, Gould KL, McCollum D. The SIN kinase Sid2 regulates cytoplasmic retention of the S. pombe Cdc14-like phosphatase Clp1. Curr Biol. 2008 Oct 28; 18(20):1594-9.
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Bach H, Papavinasasundaram KG, Wong D, Hmama Z, Av-Gay Y. Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B. Cell Host Microbe. 2008 May 15; 3(5):316-22.
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Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G. Endocrine regulation of energy metabolism by the skeleton. Cell. 2007 Aug 10; 130(3):456-69.
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Vivanco I, Palaskas N, Tran C, Finn SP, Getz G, Kennedy NJ, Jiao J, Rose J, Xie W, Loda M, Golub T, Mellinghoff IK, Davis RJ, Wu H, Sawyers CL. Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. Cancer Cell. 2007 Jun; 11(6):555-69.
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Jin QW, Ray S, Choi SH, McCollum D. The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast. Mol Biol Cell. 2007 Aug; 18(8):2924-34.