Disease Models, Animal

"Disease Models, Animal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Descriptor ID	D004195
MeSH Number(s)	C22.232 E05.598.500 E05.599.395.080
Concept/Terms	Disease Models, Animal Disease Models, Animal Animal Disease Model Animal Disease Models Disease Model, Animal

Below are MeSH descriptors whose meaning is more general than "Disease Models, Animal".

Diseases [C]
Animal Diseases [C22]
Disease Models, Animal [C22.232]
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Models, Animal [E05.598]
Disease Models, Animal [E05.598.500]
Models, Theoretical [E05.599]
Models, Biological [E05.599.395]
Disease Models, Animal [E05.599.395.080]

Below are MeSH descriptors whose meaning is related to "Disease Models, Animal".

Below are MeSH descriptors whose meaning is more specific than "Disease Models, Animal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Disease Models, Animal" by people in this website by year, and whether "Disease Models, Animal" was a major or minor topic of these publications.

Bar chart showing 1627 publications over 31 distinct years, with a maximum of 105 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	3	3
1997	0	5	5
1998	0	3	3
1999	0	5	5
2000	2	9	11
2001	5	14	19
2002	4	25	29
2003	2	33	35
2004	7	38	45
2005	7	41	48
2006	5	45	50
2007	5	54	59
2008	9	49	58
2009	11	51	62
2010	16	42	58
2011	11	60	71
2012	9	50	59
2013	6	62	68
2014	11	75	86
2015	10	66	76
2016	7	98	105
2017	7	78	85
2018	6	93	99
2019	7	76	83
2020	9	76	85
2021	7	62	69
2022	0	32	32
2023	1	27	28
2024	19	42	61
2025	4	78	82
2026	3	45	48

Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.

Megathlin HR, Burzenski L, Coleman DA, Albert B, Farley ML, Brehm MA, Greiner DL, Shultz LD. NSG Mice Lacking Apoe: An Immunodeficient Mouse Model of Atherosclerosis. FASEB J. 2026 Oct 31; 40(20).

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Austermeier S, Cheng KO, Dietschmann A, Vascelli G, Montaño DE, Hitzler SUJ, Skurk KS, Fernández-Fernández C, Saloni S, Westermann S, Jaeger M, Jablonowski N, Wisgott S, Elshafee O, Brachelente C, de Graaf DM, Próchnicki T, Latz E, Wirtz S, Becker C, Renga G, Oikonomou V, Hube B, Donders GGG, Pekmezovic M, Zelante T, Gresnigt MS. Local albumin excess exacerbates Candida albicans-induced inflammasome activation linked with hyperinflammation during vulvovaginal candidiasis. Nat Commun. 2026 Oct 29; 17(1).

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Han L, Rodriguez E, Shaw C, Kurian J, Capuano S, Escalante GM, Muniraju M, Jung K, Mutsvunguma LZ, Engelman K, Jung J, Ross CN, Reidel IG, Ogembo JG. Newly developed monoclonal antibodies for marmoset immunosuppression enable KSHV lytic replication and salivary shedding: A promising model for KSHV pathogenesis studies. PLoS Pathog. 2026 Oct; 22(10):e1014698.

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Simmons A, Wilferd SF, Campagnuolo S, Pena V, Bimonte-Nelson H, Newbern J, Sirianni RW, Plaisier CL, Stabenfeldt SE. Differential sex-dependent responses of circulating steroid hormones and cortical gene expression in a traumatic brain injury model. Sci Adv. 2026 Oct 23; 12(43):eaei5171.

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Olde Heuvel F, Pagliarini M, Sun F, Lupu L, Zhao Z, Cui L, Zhang J, Halbgebauer R, Mannes M, Boeckers TM, Knöll B, Lien E, Mollnes TE, Huber-Lang M, Roselli F. Loss of C3 and CD14 reduces region-specific neuroinflammation in a murine polytrauma model. Inflamm Res. 2026 Sep 24; 75(1).

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Maguire AS, Ta NL, Gross AL, Garrett CJ, Zimmerman AD, Diffie EB, Osterhoudt DE, Pacer SH, Mitchell ML, Cannon JS, Hall PI, Sandey M, Cole RC, Seyfried TN, Gray-Edwards HL, Sena-Esteves M, Martin DR. Intravenous gene therapy improves life span and clinical outcomes in a feline model of Sandhoff disease. Sci Transl Med. 2026 09 09; 18(866):eadx2447.

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Boudi A, Sapp E, Li YY, Shing K, Kegel-Gleason K, Petrozziello T, Sadri-Vakili G, Aronin N, DiFiglia M, Li X. Early reduction of myelin-associated glycoprotein at myelin membranes in Huntington's disease. Exp Neurol. 2026 Dec; 406:115995.

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Perez NM, Ranjitkar S, Jordan N, Gregory KJ, Schneider SS, Dwyer DF, Mathias CB. Context-dependent regulation of mast cell-mediated food allergy in C57BL/6J mice. J Allergy Clin Immunol. 2026 Nov; 158(5):1347-1360.e9.

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Belgrad J, Summers A, Landles C, Greene JR, Hildebrand S, Knox E, Sapp E, Yamada N, Furgal R, Miller R, Osborne GF, Chase K, Luu E, Freedman J, Bramato B, McHugh N, Nnah I, Benoit V, O'Reilly D, Greer P, Bates GP, Vogt TF, Lee R, Howland D, DiFiglia M, Aronin N, Khvorova A. Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington's disease pathogenesis in mice. Sci Transl Med. 2026 Aug 12; 18(862):eaea3104.

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Wang Y, Peng W, Fan W, Xiao H, Guo S, Tang Z, Qin J. Yakuchinone B Ameliorates DSS-Induced Colitis by Modulating the Gut Microbiota-Metabolite Axis. Nutrients. 2026 Aug 12; 18(16).

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