Below are the most recent publications written about "Dependovirus" by people in Profiles.
-
Lonfat N, Moreno-Leon L, Punzo C, Khanna H. Update on Gene Therapy Clinical Trials for Eye Diseases. Hum Gene Ther. 2025 Oct; 36(19-20):1287-1300.
-
Xing R, Xu M, Reil D, Destefano A, Cui M, Liu N, Liang J, Xu G, Luo L, Xu M, Zhang F, Tai PWL, Wei Y, Gruntman AM, Flotte TR, Gao G, Wang D. A single amino acid variant in the variable region I of AAV capsid confers liver detargeting. PLoS Pathog. 2025 Sep; 21(9):e1013533.
-
Eichler F, Cataltepe OI, Daci R, Puri AS, Taghian T, Jiang X, Shazeeb MS, Kuhn A, Hader A, Celik H, Vardar Z, Lewis CJ, Artinian R, Nagy A, Vachha B, Thompson R, Gallagher T, Bateman S, Parzych J, Spanakis SG, Vaughn TA, Pier K, De Boever E, Abbott MA, D Ambrosio E, Kokoski D, Blackwood M, Drummond E, Ratai EM, Townsend EL, McLaughlin H, Tifft CJ, Keeler AM, Sena-Esteves M, Gray-Edwards HL, Flotte TR. Dual-vector rAAVrh8 gene therapy for GM2 gangliosidosis: a phase 1/2 trial. Nat Med. 2025 Sep; 31(9):2927-2935.
-
Ardeshir A, O'Hagan D, Mehta I, Shandilya S, Hopkins LLJ, Adamson L, Kuroda MJ, Hahn PA, da Costa LAB, Fuchs SP, Martinez-Navio JM, Gardner MR, Van Rompay KKA, Magnani DM, Lifson JD, Gao G, Farzan M, Desrosiers RC, Das J, Martins MA. Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life. Nature. 2025 Sep; 645(8082):1020-1028.
-
Iwanowicz A, Boudi A, Seeley C, Sapp E, Miller R, Liu S, Chase K, Shing K, Batista AR, Siena-Esteves M, Aronin N, DiFiglia M, Kegel-Gleason KB. Intrastriatal Delivery of a Zinc Finger Protein Targeting the Mutant HTT Gene Allele Obviates Lipid Phenotypes in Brain and Plasma in Huntington's Disease?Mice. Hum Gene Ther. 2025 Aug; 36(15-16):1083-1094.
-
Wang Y, Liu J, Zhu S, Hu S, Chen X, Mandon E, Tran NT, Zhang S, Qi Y, Ma H, He R, Cao Y, Su Q, Gallagher TL, Li Z, Zhou C, Tai PWL, Gao G, Xie J. miR-375 protects against acetaminophen-induced acute liver failure by orchestrating pharmacogene expression. Mol Ther. 2025 Oct 01; 33(10):4874-4888.
-
Manek R, Huang W, Huang Y, Guo L, Cornell CS, Shazeeb MS, Verbitsky A, Jackson R, Johnson J, Berthelette P, Yu D, Pfister EL, Bangari D, Ying X, Kumar D, Mueller C, Kyostio-Moore S. Blood phenylalanine lowering partially reverses white matter changes in a mouse model of phenylketonuria. Mol Ther. 2025 Sep 03; 33(9):4303-4319.
-
Liu H, Liu N, Zhou C, Du A, Kapadia M, Tai PWL, Barton E, Gao G, Wang D. High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling. EMBO Mol Med. 2025 Jun; 17(6):1475-1494.
-
Byrne BJ, Flanigan KM, Matesanz SE, Finkel RS, Waldrop MA, D'Ambrosio ES, Johnson NE, Smith BK, B?nnemann C, Carrig S, Rossano JW, Greenberg B, Lalaguna L, Lara-Pezzi E, Subramony S, Corti M, Mercado-Rodriguez C, Leon-Astudillo C, Ahrens-Nicklas R, Bharucha-Goebel D, Gao G, Gessler DJ, Hwu WL, Chien YH, Lee NC, Boye SL, Boye SE, George LA. Current clinical applications of AAV-mediated gene therapy. Mol Ther. 2025 Jun 04; 33(6):2479-2516.
-
Green EA, Fu Q, Ndahiro N, Leibiger TM, Wang Y, Lee Y, Lee KH, Betenbaugh M, Yoon S, McNally DJ. Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing. Biotechnol Bioeng. 2025 Jul; 122(7):1640-1655.