Below are the most recent publications written about "Transgenes" by people in Profiles.
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Tang Q, Pires-Ferreira D, Mueller C, Gruntman AM, Flotte TR. Optimization of Alpha-1 Antitrypsin Expression from Adeno-Associated Virus Vectors. Hum Gene Ther. 2026 Jul; 37(13-14):609-617.
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Xicluna R, Yamada K, Gonzalez-Visiedos M, Greenwood CM, Zaugg D, Waiz D, Steiner G, Hahn K, Schwandt T, Otteneder MB, Biswas M, Mu?oz-Melero M, Kumar SRP, Herzog RW, Haegel H. Transient prophylactic immunosuppression with abatacept or dasatinib prevents immune responses in AAV gene transfer. Mol Ther. 2026 Jul 01; 34(7):3805-3819.
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Cui M, Cheng SY, Liang J, McGowan J, Xu M, Xu G, Luo L, Wu J, Harman CD, Jacobson AL, Kapeller LE, Mayes MA, Namkung S, Sharma T, Leland TB, Zhang F, Yip M, Rossmiller B, Xue T, Chen X, Boonying W, Lotun A, Wang D, Su Q, Xie J, Wei Y, Rothstein AM, Gregory-Ksander MS, Komaromy A, Tian B, Lin H, Punzo C, Tai PWL, Gao G. Modification of the VP1u region boosts transduction of adeno-associated virus vectors for ocular gene therapy. Mol Ther. 2026 May 06; 34(5):2781-2800.
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Godin P, Nagykery N, Sicher N, Barnes JL, Miller AG, Bunner C, Thompson AK, Kano M, Gao G, Wang D, Donahoe PK, Rhodes L, Brake DA, Conlon TJ, Swanson WF, Vansandt LM, P?pin D. Gene therapy delivery of anti-M?llerian hormone in prepubertal female domestic cats induces long-term sterilization. Nat Commun. 2025 Nov 28; 16(1):10747.
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Moyer AJ, Chrabasz JA, Barcus AK, Cheng J, Capps MES, Lalonde RL, Mosimann C, Thyme SB. Genetic context of transgene insertion can influence neurodevelopment in zebrafish. Genetics. 2025 11 12; 231(3).
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Peterman EL, Ploessl DS, Love KS, Sanabria V, Daniels RF, Johnstone CP, Godavarti DR, Kabaria SR, Oakes CG, Pai AA, Galloway KE. High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes. Nucleic Acids Res. 2025 Jun 06; 53(11).
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Liu H, Liu N, Zhou C, Du A, Kapadia M, Tai PWL, Barton E, Gao G, Wang D. High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling. EMBO Mol Med. 2025 Jun; 17(6):1475-1494.
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Tang X, Wang H, Yin Y, Zhong G. A peptide conjugate enables systemic injection of the morpholino inducer and more durable induction of T3H38 ribozyme-controlled AAV transgene in mice. Gene Ther. 2025 03; 32(2):163-171.
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Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, De Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, Gaitan Y, Duryea J, Hannigan S, Dickinson ME, Mirochnitchenko O, Wang D, Lutz CM, Heaney JD, Gao G, Murray SA, Lagor WR. A comprehensive atlas of AAV tropism in the mouse. Mol Ther. 2025 Mar 05; 33(3):1282-1299.
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Xie Q, Chen X, Ma H, Zhu Y, Ma Y, Jalinous L, Cox GF, Weaver F, Yang J, Kennedy Z, Gruntman A, Du A, Su Q, He R, Tai PW, Gao G, Xie J. Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO Mol Med. 2024 Apr; 16(4):945-965.