Below are the most recent publications written about "Gene Editing" by people in Profiles.
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Iyer S, Daman K, Sun Y, Tutto A, Holbrook SE, Joynt AT, Yan J, Ambegaokar P, Guo D, Liu P, Stauffer JE, Maitland SA, Lee SM, Xiao Y, Huang HC, Zhu LJ, Gallagher TL, Cox GA, Keeler AM, Siegwart DJ, Emerson CP, Wolfe SA. SORT LNPs encapsulating Cas9 mRNA achieve efficient editing in skeletal muscle in a dystrophic mouse model. Mol Ther. 2026 Jul 01; 34(7):3885-3902.
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Castelli JMP, Poljakov K, Jwa Y, Cunningham R, Cassidy ME, Gray MD, Sanchez Gaytan JN, Enstrom MR, Gastelum G, Wang Z, Linton JD, Rongvaux A, Taylor JJ, Adair JE. In vivo production of an anti-HIV antibody in mice by non-viral gene knockin in primate hematopoietic stem and progenitor cells. Mol Ther. 2026 May 06; 34(5):2754-2769.
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Gottimukkala KSV, Lane DD, Cunningham R, Malik HS, Jwa Y, Cassidy ME, Castelli JMP, Enstrom MR, Poljakov K, Gastelum G, Ho SH, Tassa C, Adair JE. CRISPR-AuNP: physicochemical optimization of a gold nanoparticle platform for cost-effective and modular non-viral gene editing in HSPCs. Gene Ther. 2026 03; 33(2):188-202.
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Luo D, Wang N, Major-Monfried H, Ralls J, Rha S, Maitland SA, Ponnienselvan K, Yamada M, Bauer DE, Wolfe SA, Kentsis A. Modular Platform for Therapeutic Drug Delivery Using Trifunctional Bio-Orthogonal Macromolecular Conjugates. Bioconjug Chem. 2025 11 19; 36(11):2472-2486.
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Lonfat N, Moreno-Leon L, Punzo C, Khanna H. Update on Gene Therapy Clinical Trials for Eye Diseases. Hum Gene Ther. 2025 10; 36(19-20):1287-1300.
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Alves CRR, Das S, Krishnan V, Ha LL, Fox LR, Stutzman HE, Shamber CE, Kalailingam P, McCarthy S, Lino Cardenas CL, Fong CE, Imai T, Mitra S, Yun S, Wood RK, Benning FMC, Roh K, Lawton J, Kim N, Silverstein RA, Ferreira da Silva J, de la Cruz D, Richa R, Xie J, Gray-Edwards HL, Malhotra R, Chung DY, Chao LH, Tsai SQ, Maguire CA, Lindsay ME, Kleinstiver BP, Musolino PL. Treatment of a severe vascular disease using a bespoke CRISPR-Cas9 base editor in mice. Nat Biomed Eng. 2026 May; 10(5):952-967.
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Gao J, Bamidele N, Pires-Ferreira D, Zheng C, Destefano A, Cheng H, Tang Q, Cao Y, Xie J, Gao G, Gruntman A, Sontheimer E, Flotte TR, Xue W. A compact base editor rescues AATD-associated liver and lung disease in mouse models. Mol Ther. 2025 11 05; 33(11):5817-5828.
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Oikemus S, Hu K, Shin M, Idrizi F, Goodman-Khan A, Kolb A, Ghanta KS, Lee J, Wagh A, Wolfe SA, Zhu LJ, Watts JK, Lawson ND. Identifying optimal conditions for precise knock-in of exogenous DNA into the zebrafish genome. Development. 2025 Jun 15; 152(12).
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Zheng C, Zhang G, Dean LJ, Sontheimer EJ, Xue W. The reverse transcriptase domain of prime editors contributes to DNA repair in mammalian cells. Nat Biotechnol. 2026 Jan; 44(1):146-153.
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Kyawe PP, Liu P, Jiang Z, Bradley ES, Cicuto T, Trombly MI, Silverman N, Fitzgerald KA, McDougall WM, Wang JP. CRISPR editing of candidate host factors that impact influenza A virus infection. Microbiol Spectr. 2025 Mar 04; 13(3):e0262724.