Below are the most recent publications written about "Directed Molecular Evolution" by people in Profiles.
-
Rosener B, Sayin S, Oluoch PO, García González AP, Mori H, Walhout AJ, Mitchell A. Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host. Elife. 2020 11 30; 9.
-
Hill ME, MacPherson DJ, Wu P, Julien O, Wells JA, Hardy JA. Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. ACS Chem Biol. 2016 06 17; 11(6):1603-12.
-
Hochbaum DR, Zhao Y, Farhi SL, Klapoetke N, Werley CA, Kapoor V, Zou P, Kralj JM, Maclaurin D, Smedemark-Margulies N, Saulnier JL, Boulting GL, Straub C, Cho YK, Melkonian M, Wong GK, Harrison DJ, Murthy VN, Sabatini BL, Boyden ES, Campbell RE, Cohen AE. All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins. Nat Methods. 2014 Aug; 11(8):825-33.
-
Wang Y, Khan IF, Boissel S, Jarjour J, Pangallo J, Thyme S, Baker D, Scharenberg AM, Rawlings DJ. Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus. Nucleic Acids Res. 2014 Jun; 42(10):6463-75.
-
Mukherjee S, Thompson LK, Godin S, Schackwitz W, Lipzen A, Martin J, Blanchard JL. Population level analysis of evolved mutations underlying improvements in plant hemicellulose and cellulose fermentation by Clostridium phytofermentans. PLoS One. 2014; 9(1):e86731.
-
Thyme SB, Boissel SJ, Arshiya Quadri S, Nolan T, Baker DA, Park RU, Kusak L, Ashworth J, Baker D. Reprogramming homing endonuclease specificity through computational design and directed evolution. Nucleic Acids Res. 2014 Feb; 42(4):2564-76.
-
Huber KL, Olson KD, Hardy JA. Robust production of a peptide library using methodological synchronization. Protein Expr Purif. 2009 Oct; 67(2):139-47.
-
Rando OJ. Evolution in a test tube: the hatchet before the scalpel. Cell. 2008 Nov 28; 135(5):789-91.
-
Vázquez-Limón C, Vega-Badillo J, Martínez A, Espinosa-Molina G, Gosset G, Soberón X, López-Munguía A, Osuna J. Growth rate of a non-fermentative Escherichia coli strain is influenced by NAD+ regeneration. Biotechnol Lett. 2007 Dec; 29(12):1857-63.
-
Li Y, Moysey R, Molloy PE, Vuidepot AL, Mahon T, Baston E, Dunn S, Liddy N, Jacob J, Jakobsen BK, Boulter JM. Directed evolution of human T-cell receptors with picomolar affinities by phage display. Nat Biotechnol. 2005 Mar; 23(3):349-54.