Spermatozoa

"Spermatozoa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.

Descriptor ID	D013094
MeSH Number(s)	A05.360.490.890 A11.497.760
Concept/Terms	Spermatozoa Spermatozoa Spermatozoon Sperm X-Chromosome-Bearing Sperm X-Chromosome-Bearing Sperm Sperm, X-Chromosome-Bearing Sperms, X-Chromosome-Bearing X Chromosome Bearing Sperm X-Chromosome-Bearing Sperms X-Bearing Sperm Sperm, X-Bearing Sperms, X-Bearing X Bearing Sperm X-Bearing Sperms Y-Chromosome-Bearing Sperm Y-Chromosome-Bearing Sperm Sperm, Y-Chromosome-Bearing Sperms, Y-Chromosome-Bearing Y Chromosome Bearing Sperm Y-Chromosome-Bearing Sperms Y-Bearing Sperm Sperm, Y-Bearing Sperms, Y-Bearing Y Bearing Sperm Y-Bearing Sperms

Below are MeSH descriptors whose meaning is more general than "Spermatozoa".

Anatomy [A]
Urogenital System [A05]
Genitalia [A05.360]
Germ Cells [A05.360.490]
Spermatozoa [A05.360.490.890]
Cells [A11]
Germ Cells [A11.497]
Spermatozoa [A11.497.760]

Below are MeSH descriptors whose meaning is related to "Spermatozoa".

Below are MeSH descriptors whose meaning is more specific than "Spermatozoa".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Spermatozoa" by people in this website by year, and whether "Spermatozoa" was a major or minor topic of these publications.

Bar chart showing 215 publications over 31 distinct years, with a maximum of 14 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1997	2	0	2
1998	5	0	5
1999	6	2	8
2000	4	1	5
2001	2	2	4
2002	3	2	5
2003	7	5	12
2004	7	4	11
2005	3	2	5
2006	3	1	4
2007	3	3	6
2008	4	3	7
2009	7	0	7
2010	4	5	9
2011	0	5	5
2012	7	1	8
2013	8	3	11
2014	7	1	8
2015	8	3	11
2016	3	1	4
2017	4	2	6
2018	11	3	14
2019	3	3	6
2020	3	5	8
2021	7	4	11
2022	0	4	4
2023	1	5	6
2024	7	2	9
2025	7	2	9
2026	3	0	3

Below are the most recent publications written about "Spermatozoa" by people in Profiles.

Holdaway JA, Saini L, Coil-Otto R, Nayyab S, Taghavi M, Visconti P, Georg GI. Development of TSSK1 and TSSK2 Targeted Degraders Reveals Sperm Machinery for Protein Degradation and Potential for Nonhormonal Male Contraception. J Med Chem. 2026 Jun 25; 69(12):14236-14254.

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Galambos NS, Crocker OJ, Schneider BK, Allerton KS, Gross KE, Schneider AE, Lynch J, Yukselen O, Kucukural A, Conine CC. tRNA-derived RNA processing in sperm transmits non-genetically inherited phenotypes to offspring in C. elegans. Nat Commun. 2026 Mar 15; 17(1).

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Cecchini K, Zamani M, Ajaykumar N, Vega-Badillo J, Bagci A, Bailey S, Zamore PD, Gainetdinov I. Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness. Nature. 2026 04; 652(8109):508-516.

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Violante S, Kyaw A, Kouatli L, Paladugu K, Apostolakis L, Jenks M, Johnson A, Sheldon RD, Whitten D, Schilmiller AL, Visconti PE, Cross JR, Levin LR, Buck J, Balbach M. Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase. Proc Natl Acad Sci U S A. 2025 Sep 30; 122(39):e2506417122.

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Cannarella R, Rando OJ, Chamayou S, Romano S, Guglielmino A, Yin Q, Mancuso F, Arato I, Lilli C, Brancorsini S, Farinacci S, Luca G, Leggio L, Iraci N, Lundy SD, La Vignera S, Calogero AE. Sperm insulin-like growth factor 2 protein levels: implications for early embryo development. Reprod Biomed Online. 2026 02; 52(2):105202.

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Fissore RA, Lopes EM, Carpentiero F. Zebrafish sperm outsource activation to eggs' protease-activated receptors. PLoS Biol. 2025 Jun; 23(6):e3003214.

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Luque GM, Jablo?ski M, Schiavi-Ehrenhaus LJ, Del Prado RC, Balbach M, Romarowski A, Martin-Hidalgo D, Visconti PE, Krapf D, Darszon A, Krapf D, Buck J, Levin LR, Buffone MG. Bovine serum albumin-induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation. J Physiol. 2025 05; 603(9):2633-2653.

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Gustafsson HT, Ferguson L, Galan C, Yu T, Upton H, Kaymak E, Weng Z, Collins K, Rando OJ. Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR. Elife. 2025 Apr 25; 14.

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Nayyab S, Gervasi MG, Tourzani DA, Shamailova Y, Akizawa H, Taghavi M, Cui W, Fissore R, Salicioni AM, Georg GI, Snyder E, Visconti PE. Identification of TSSK1 and TSSK2 as Novel Targets for Male Contraception. Biomolecules. 2025 04 18; 15(4).

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Yang CH, Rando OJ. Paternal Effects in Mammals: Challenges and Opportunities. Annu Rev Biochem. 2025 06; 94(1):253-278.

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