Below are the most recent publications written about "Genetic Vectors" by people in Profiles.
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Wan F, He J, Ma H, PiresFerreira D, Kumanan V, Lee JS, Chen X, He R, Su Q, Gallagher TL, Zhu S, Cabrera GT, Zhao L, Shen J, Gruntman A, Brown RH, Xu Z, Gao G, Xie J. Intravenous administration of an engineered AAV9-gene-silencing vector suppresses human SOD1 and extends survival in an ALS mouse model. Nat Commun. 2026 06 25; 17(1).
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Khanduja S, Raman V, Hall CL, Howell LM, Van Dessel N, Forbes NS. Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory. Cell Rep Med. 2026 Jun 16; 7(6):102839.
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Chen X, Xie Q, Nath SJ, Tang M, Ma H, G?nes Y?, Sharma T, Liu H, Cui M, Du A, Lu M, Liu SY, Wassamon B, Xu M, Wu JY, Su Q, Fitzgibbons TP, Liu J, Wan F, Kumanan V, He R, Ma Y, Yang J, Gray-Edwards HL, Gallagher TL, Tai PWL, Gao G, Xie J. Long-term comparative analysis of AAV9-mediated gene replacement therapies for spinal muscular atrophy in mice. Nat Commun. 2026 May 23; 17(1).
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Tang Q, Pires-Ferreira D, Mueller C, Gruntman AM, Flotte TR. Optimization of Alpha-1 Antitrypsin Expression from Adeno-Associated Virus Vectors. Hum Gene Ther. 2026 Jul; 37(13-14):609-617.
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Wang J, Turgeon CT, Loken PR, Gray-Edwards H, Gao G, Tortorelli S, Wang D, Strauss KA. Systemic dual-gene therapy reverses biochemical intoxication in the central metabolic compartment of Bckdha-/- mice. Mol Ther. 2026 Aug 05; 34(8):4569-4580.
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Arjomandnejad M, Essien K, Sylvia K, Blackwood M, Tutto A, Katz E, Tang Q, Harris JE, Keeler AM. AAVrh32.33 capsid demonstrates unexpected dermal tropism regardless of immunodominant epitope. Mol Ther. 2026 Aug 05; 34(8):4531-4545.
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Wu HL, Webb GM, Fuchs SP, Pessoa CT, Hwang JM, Fisher HK, McCullen AJ, Humkey MC, Brown MK, Waytashek CM, Boyle CD, Kukula KA, Potter SK, Devlin G, Elmore ZC, Hull JA, Zikos J, Swanson T, Armantrout K, Chun K, Crank H, Bailey L, White R, Barber-Axthelm A, Fischer M, Smedley JV, Axthelm MK, Fennessey CM, Keele BF, Desrosiers RC, Magnani DM, Asokan A, Sacha JB. Adeno-associated virus gene therapy-mediated CCR5 blockade suppresses virus replication long term in SHIV-infected macaques. Sci Transl Med. 2026 Apr 29; 18(847):eadw1976.
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Xicluna R, Yamada K, Gonzalez-Visiedos M, Greenwood CM, Zaugg D, Waiz D, Steiner G, Hahn K, Schwandt T, Otteneder MB, Biswas M, Mu?oz-Melero M, Kumar SRP, Herzog RW, Haegel H. Transient prophylactic immunosuppression with abatacept or dasatinib prevents immune responses in AAV gene transfer. Mol Ther. 2026 Jul 01; 34(7):3805-3819.
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Parajuli S, Gallagher T, Flotte TR. Immune Toxicities in AAV Gene Therapy: Overview for Clinicians. Int J Mol Sci. 2026 Mar 31; 27(7).
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Saylam E, D'ambrosio ES, Pesco MT, Gushchina LV. Adeno-Associated Virus Toxicity in Duchenne Muscular Dystrophy: Mechanisms and Clinical Considerations. Genes (Basel). 2026 Feb 27; 17(3).