Genetic Vectors

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"Genetic Vectors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.

Descriptor ID	D005822
MeSH Number(s)	G05.360.337
Concept/Terms	Genetic Vectors Genetic Vectors Genetic Vector Vector, Genetic Vectors, Genetic Shuttle Vectors Shuttle Vectors Shuttle Vector Vector, Shuttle Vectors, Shuttle Cloning Vectors Cloning Vectors Cloning Vector Vector, Cloning Vectors, Cloning

Below are MeSH descriptors whose meaning is more general than "Genetic Vectors".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genetic Vectors [G05.360.337]

Below are MeSH descriptors whose meaning is related to "Genetic Vectors".

Below are MeSH descriptors whose meaning is more specific than "Genetic Vectors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genetic Vectors" by people in this website by year, and whether "Genetic Vectors" was a major or minor topic of these publications.

Bar chart showing 536 publications over 31 distinct years, with a maximum of 31 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	6	4	10
1996	5	3	8
1997	3	6	9
1998	4	8	12
1999	4	3	7
2000	6	5	11
2001	9	4	13
2002	15	15	30
2003	9	16	25
2004	11	5	16
2005	9	14	23
2006	3	4	7
2007	12	11	23
2008	14	10	24
2009	8	12	20
2010	11	8	19
2011	8	13	21
2012	5	7	12
2013	13	13	26
2014	4	16	20
2015	7	14	21
2016	5	12	17
2017	12	19	31
2018	10	15	25
2019	9	12	21
2020	15	6	21
2021	9	7	16
2022	5	5	10
2023	4	5	9
2024	13	10	23
2025	3	3	6

Below are the most recent publications written about "Genetic Vectors" by people in Profiles.

Keeler AM, Zhan W, Ram S, Fitzgerald KA, Gao G. The curious case of AAV immunology. Mol Ther. 2025 May 07; 33(5):1946-1965.

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Wang D, Stevens G, Flotte TR. Gene therapy then and now: A look back at changes in the field over the past 25 years. Mol Ther. 2025 May 07; 33(5):1889-1902.

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Wang J, Poskitt LE, Gallagher J, Puffenberger EG, Wynn RM, Shishodia G, Chuang DT, Beever J, Hardin DL, Brigatti KW, Baker WC, Gately R, Bertrand S, Rodrigues A, Benatti HR, Taghian T, Hall E, Prestigiacomo R, Liang J, Chen G, Zhou X, Ren L, Liu N, He R, Su Q, Xie J, Jiang Z, Gruntman A, Gray-Edwards H, Gao G, Strauss KA, Wang D. BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease. Sci Transl Med. 2025 Feb 26; 17(787):eads0539.

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Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, De Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, Gaitan Y, Duryea J, Hannigan S, Dickinson ME, Mirochnitchenko O, Wang D, Lutz CM, Heaney JD, Gao G, Murray SA, Lagor WR. A comprehensive atlas of AAV tropism in the mouse. Mol Ther. 2025 Mar 05; 33(3):1282-1299.

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Laforet GA. Thrombotic Microangiopathy Associated with Systemic Adeno-Associated Virus Gene Transfer: Review of Reported Cases. Hum Gene Ther. 2025 Feb; 36(3-4):64-76.

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Wang Y, Fu Q, Sha S, Yoon S. Interferon inhibitors increase rAAV production in HEK293 cells. J Biotechnol. 2025 Mar; 399:9-18.

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Banou L, Sarrafpour S, Teng CC, Liu J. Ocular Gene Therapy: An Overview of Viral Vectors, Immune Responses, and Future Directions. Yale J Biol Med. 2024 12; 97(4):491-503.

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Daci R, Gray-Edwards H, Shazeeb MS, Vardar Z, Vachha B, Cataltepe OI, Flotte TR. Neuroimaging Applications for the Delivery and Monitoring of Gene Therapy for Central Nervous System Diseases. Hum Gene Ther. 2024 Nov; 35(21-22):886-895.

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Wang JH, Zhan W, Gallagher TL, Gao G. Recombinant adeno-associated virus as a delivery platform for ocular gene therapy: A comprehensive review. Mol Ther. 2024 Dec 04; 32(12):4185-4207.

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Du A, Yang K, Zhou X, Ren L, Liu N, Zhou C, Liang J, Yan N, Gao G, Wang D. Systemic gene therapy corrects the neurological phenotype in a mouse model of NGLY1 deficiency. JCI Insight. 2024 Oct 08; 9(19).

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