Genetic Vectors

"Genetic Vectors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.

Descriptor ID	D005822
MeSH Number(s)	G05.360.337
Concept/Terms	Genetic Vectors Genetic Vectors Genetic Vector Vector, Genetic Vectors, Genetic Shuttle Vectors Shuttle Vectors Shuttle Vector Vector, Shuttle Vectors, Shuttle Cloning Vectors Cloning Vectors Cloning Vector Vector, Cloning Vectors, Cloning

Below are MeSH descriptors whose meaning is more general than "Genetic Vectors".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genetic Vectors [G05.360.337]

Below are MeSH descriptors whose meaning is related to "Genetic Vectors".

Below are MeSH descriptors whose meaning is more specific than "Genetic Vectors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genetic Vectors" by people in this website by year, and whether "Genetic Vectors" was a major or minor topic of these publications.

Bar chart showing 572 publications over 31 distinct years, with a maximum of 32 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	5	3	8
1997	3	6	9
1998	4	8	12
1999	4	3	7
2000	6	5	11
2001	9	4	13
2002	15	15	30
2003	9	16	25
2004	11	6	17
2005	10	14	24
2006	5	4	9
2007	13	11	24
2008	16	12	28
2009	8	15	23
2010	11	8	19
2011	8	11	19
2012	4	8	12
2013	13	12	25
2014	4	17	21
2015	7	15	22
2016	7	12	19
2017	12	20	32
2018	11	16	27
2019	10	13	23
2020	15	6	21
2021	9	7	16
2022	5	4	9
2023	4	5	9
2024	15	9	24
2025	10	15	25
2026	7	2	9

Below are the most recent publications written about "Genetic Vectors" by people in Profiles.

Khanduja S, Raman V, Hall CL, Howell LM, Van Dessel N, Forbes NS. Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory. Cell Rep Med. 2026 Jun 16; 7(6):102839.

View in: PubMed
Tang Q, Pires-Ferreira D, Mueller C, Gruntman AM, Flotte TR. Optimization of Alpha-1 Antitrypsin Expression from Adeno-Associated Virus Vectors. Hum Gene Ther. 2026 Jul; 37(13-14):609-617.

View in: PubMed
Wu HL, Webb GM, Fuchs SP, Pessoa CT, Hwang JM, Fisher HK, McCullen AJ, Humkey MC, Brown MK, Waytashek CM, Boyle CD, Kukula KA, Potter SK, Devlin G, Elmore ZC, Hull JA, Zikos J, Swanson T, Armantrout K, Chun K, Crank H, Bailey L, White R, Barber-Axthelm A, Fischer M, Smedley JV, Axthelm MK, Fennessey CM, Keele BF, Desrosiers RC, Magnani DM, Asokan A, Sacha JB. Adeno-associated virus gene therapy-mediated CCR5 blockade suppresses virus replication long term in SHIV-infected macaques. Sci Transl Med. 2026 Apr 29; 18(847):eadw1976.

View in: PubMed
Parajuli S, Gallagher T, Flotte TR. Immune Toxicities in AAV Gene Therapy: Overview for Clinicians. Int J Mol Sci. 2026 Mar 31; 27(7).

View in: PubMed
Saylam E, D'ambrosio ES, Pesco MT, Gushchina LV. Adeno-Associated Virus Toxicity in Duchenne Muscular Dystrophy: Mechanisms and Clinical Considerations. Genes (Basel). 2026 Feb 27; 17(3).

View in: PubMed
Lewis CJ, D'Souza P, Johnston JM, Acosta MT, Farmer C, Baker EH, Crowell A, Mojica Y, Ashraf S, Joseph L, V?zina G, Quezado Z, Yousef MH, Vardar Z, Shazeeb MS, Corti M, Blackwood M, Coleman K, Batista R, Thurm A, De Boever E, Gahl WA, Byrne BJ, Flotte TR, Jiang X, Gross AL, Keeler AM, Gray-Edwards H, Martin DR, Sena-Esteves M, Tifft CJ. AAV9 Gene Therapy in Type II GM1 Gangliosidosis - A Phase 1-2 Trial. N Engl J Med. 2026 Mar 26; 394(12):1184-1194.

View in: PubMed
Castelli JMP, Poljakov K, Jwa Y, Cunningham R, Cassidy ME, Gray MD, Sanchez Gaytan JN, Enstrom MR, Gastelum G, Wang Z, Linton JD, Rongvaux A, Taylor JJ, Adair JE. In vivo production of an anti-HIV antibody in mice by non-viral gene knockin in primate hematopoietic stem and progenitor cells. Mol Ther. 2026 May 06; 34(5):2754-2769.

View in: PubMed
Cui M, Cheng SY, Liang J, McGowan J, Xu M, Xu G, Luo L, Wu J, Harman CD, Jacobson AL, Kapeller LE, Mayes MA, Namkung S, Sharma T, Leland TB, Zhang F, Yip M, Rossmiller B, Xue T, Chen X, Boonying W, Lotun A, Wang D, Su Q, Xie J, Wei Y, Rothstein AM, Gregory-Ksander MS, Komaromy A, Tian B, Lin H, Punzo C, Tai PWL, Gao G. Modification of the VP1u region boosts transduction of adeno-associated virus vectors for ocular gene therapy. Mol Ther. 2026 May 06; 34(5):2781-2800.

View in: PubMed
Hoyle B, Bello D, Hill J, Das S, Kim J. Imaged Capillary Isoelectric Focusing (icIEF) Platform for Characterization of Charge Variants of Adeno-Associated Virus (AAV) Capsids and Impact on their Transduction Efficiency. Curr Gene Ther. 2026; 26(2):1-16.

View in: PubMed
Hoyle B, Hill J, Bello D. Quantifying the Full-to-Empty Adeno-Associated Virus (AAV) Capsid Ratios and Their Impact on Transduction Efficiency in vitro. AAPS J. 2025 12 17; 28(1):36.

View in: PubMed

People

Explore

Similar Concepts

Top Journals