Mice, Inbred NOD

"Mice, Inbred NOD" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A strain of non-obese diabetic mice developed in Japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent diabetes mellitus in which insulitis is a major histopathologic feature, and in which genetic susceptibility is strongly MHC-linked.

Descriptor ID	D016688
MeSH Number(s)	B01.050.050.199.520.520.565 B01.050.150.900.649.313.992.635.505.500.400.565
Concept/Terms	Mice, Inbred NOD Mice, Inbred NOD Inbred NOD Mice NOD Mice, Inbred Mouse, NOD NOD Mouse Nonobese Diabetic Mice Diabetic Mice, Nonobese Mice, Nonobese Diabetic Non-Obese Diabetic Mouse Diabetic Mouse, Non-Obese Mouse, Non-Obese Diabetic Non Obese Diabetic Mouse Non-Obese Diabetic Mice Diabetic Mice, Non-Obese Mice, Non-Obese Diabetic Non Obese Diabetic Mice Mouse, Inbred NOD Inbred NOD Mouse NOD Mouse, Inbred Mice, NOD NOD Mice Nonobese Diabetic Mouse Diabetic Mouse, Nonobese Mouse, Nonobese Diabetic

Below are MeSH descriptors whose meaning is more general than "Mice, Inbred NOD".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Laboratory [B01.050.050.199]
Animals, Inbred Strains [B01.050.050.199.520]
Mice, Inbred Strains [B01.050.050.199.520.520]
Mice, Inbred NOD [B01.050.050.199.520.520.565]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Mice [B01.050.150.900.649.313.992.635.505.500]
Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
Mice, Inbred NOD [B01.050.150.900.649.313.992.635.505.500.400.565]

Below are MeSH descriptors whose meaning is related to "Mice, Inbred NOD".

Below are MeSH descriptors whose meaning is more specific than "Mice, Inbred NOD".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mice, Inbred NOD" by people in this website by year, and whether "Mice, Inbred NOD" was a major or minor topic of these publications.

Bar chart showing 323 publications over 30 distinct years, with a maximum of 19 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	6	8
1996	0	3	3
1997	0	4	4
1998	0	3	3
1999	0	2	2
2000	0	6	6
2001	0	6	6
2002	0	7	7
2003	2	16	18
2004	1	11	12
2005	0	17	17
2006	0	10	10
2007	1	9	10
2008	1	17	18
2009	0	13	13
2010	1	17	18
2011	1	18	19
2012	1	13	14
2013	0	11	11
2014	0	18	18
2015	2	13	15
2016	0	16	16
2017	0	14	14
2018	0	10	10
2019	0	16	16
2020	0	14	14
2021	0	6	6
2022	0	2	2
2023	0	8	8
2024	2	3	5

Below are the most recent publications written about "Mice, Inbred NOD" by people in Profiles.

Darguzyte M, Antczak P, Bachurski D, Hoelker P, Abedpour N, Gholamipoorfard R, Schl??er HA, Wennhold K, Thelen M, Garcia-Marquez MA, Koenig J, Schneider A, Braun T, Klawonn F, Damrat M, Rahman M, Kleid JM, Theobald SJ, Bauer E, von Kaisenberg C, Talbot SR, Shultz LD, Soper B, Stripecke R. Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles. Cells. 2024 10 12; 13(20).

View in: PubMed
Serreze DV, Dwyer JR, Racine JJ. Advancing Animal Models of Human Type 1 Diabetes. Cold Spring Harb Perspect Med. 2024 Oct 01; 14(10).

View in: PubMed
Lee J, Yurkovetskiy LA, Reiman D, Frommer L, Strong Z, Chang A, Kahaly GJ, Khan AA, Chervonsky AV. Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 Sep 03; 15(1):7688.

View in: PubMed
Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.

View in: PubMed
Racine JJ, Bachman JF, Zhang JG, Misherghi A, Khadour R, Kaisar S, Bedard O, Jenkins C, Abbott A, Forte E, Rainer P, Rosenthal N, Sattler S, Serreze DV. Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy. J Immunol. 2024 Apr 15; 212(8):1287-1306.

View in: PubMed
Racine JJ, Misherghi A, Dwyer JR, Maser R, Forte E, Bedard O, Sattler S, Pugliese A, Landry L, Elso C, Nakayama M, Mannering S, Rosenthal N, Serreze DV. HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice. J Immunol. 2023 12 15; 211(12):1792-1805.

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Ye C, Clements SA, Gu W, Geurts AM, Mathews CE, Serreze DV, Chen YG, Driver JP. Deletion of V?3+CD4+ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8+ T cells. Proc Natl Acad Sci U S A. 2023 Dec 05; 120(49):e2312039120.

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Yang J, Jiao J, Draheim KM, Yang G, Yang H, Yao LC, Shultz LD, Greiner DL, Rajagopal D, Vessillier S, Maier CC, Mohanan S, Cai D, Cheng M, Brehm MA, Keck JG. Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model. FASEB J. 2023 06; 37(6):e22995.

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Aryee KE, Shultz LD, Burzenski LM, Greiner DL, Brehm MA. NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. J Leukoc Biol. 2023 05 02; 113(5):418-433.

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Ciecko AE, Wang Y, Harleston S, Drewek A, Serreze DV, Geurts AM, Lin CW, Chen YG. Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes. J Immunol. 2023 04 01; 210(7):935-946.

View in: PubMed

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