Mice, Inbred NOD

"Mice, Inbred NOD" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A strain of non-obese diabetic mice developed in Japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent diabetes mellitus in which insulitis is a major histopathologic feature, and in which genetic susceptibility is strongly MHC-linked.

Descriptor ID	D016688
MeSH Number(s)	B01.050.050.199.520.520.565 B01.050.150.900.649.313.992.635.505.500.400.565
Concept/Terms	Mice, Inbred NOD Mice, Inbred NOD Inbred NOD Mice NOD Mice, Inbred Mouse, NOD NOD Mouse Nonobese Diabetic Mice Diabetic Mice, Nonobese Mice, Nonobese Diabetic Non-Obese Diabetic Mouse Diabetic Mouse, Non-Obese Mouse, Non-Obese Diabetic Non Obese Diabetic Mouse Non-Obese Diabetic Mice Diabetic Mice, Non-Obese Mice, Non-Obese Diabetic Non Obese Diabetic Mice Mouse, Inbred NOD Inbred NOD Mouse NOD Mouse, Inbred Mice, NOD NOD Mice Nonobese Diabetic Mouse Diabetic Mouse, Nonobese Mouse, Nonobese Diabetic

Below are MeSH descriptors whose meaning is more general than "Mice, Inbred NOD".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Laboratory [B01.050.050.199]
Animals, Inbred Strains [B01.050.050.199.520]
Mice, Inbred Strains [B01.050.050.199.520.520]
Mice, Inbred NOD [B01.050.050.199.520.520.565]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Mice [B01.050.150.900.649.313.992.635.505.500]
Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
Mice, Inbred NOD [B01.050.150.900.649.313.992.635.505.500.400.565]

Below are MeSH descriptors whose meaning is related to "Mice, Inbred NOD".

Below are MeSH descriptors whose meaning is more specific than "Mice, Inbred NOD".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mice, Inbred NOD" by people in this website by year, and whether "Mice, Inbred NOD" was a major or minor topic of these publications.

Bar chart showing 319 publications over 31 distinct years, with a maximum of 18 publications in 2003 and 2008 and 2010 and 2011 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	3	3
1997	0	4	4
1998	0	3	3
1999	0	2	2
2000	0	6	6
2001	0	6	6
2002	0	7	7
2003	2	16	18
2004	1	11	12
2005	0	17	17
2006	0	10	10
2007	1	9	10
2008	1	17	18
2009	0	13	13
2010	1	17	18
2011	1	17	18
2012	1	12	13
2013	0	9	9
2014	0	18	18
2015	2	12	14
2016	0	17	17
2017	0	14	14
2018	0	12	12
2019	0	17	17
2020	0	14	14
2021	0	7	7
2022	0	2	2
2023	0	8	8
2024	2	3	5
2025	0	3	3
2026	0	1	1

Below are the most recent publications written about "Mice, Inbred NOD" by people in Profiles.

Itoh-Nakadai A, Liang M, Shindo M, Bibi C, Tomizawa-Murasawa M, Fujiki S, Kaneko A, Kanamaru E, Hashimoto M, Kajita H, Ando Y, Kojima M, Moody J, Iwasaki M, Takagi S, Nakagawa R, Agrawal S, Amitani-Iijima H, Sato K, Sorimachi Y, Suzuki N, Fukami T, Hanada K, Morita S, Katsura K, Matsumoto T, Kobayashi M, Kato M, Negishi Y, Shirouzu M, Najima Y, Takubo K, Hon CC, Uchida N, Taniguchi S, Momozawa Y, Carninci P, Shultz LD, Saito Y, de Hoon M, Shin JW, Ishikawa F. CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting. Nat Commun. 2026 Jan 26; 17(1):101.

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Racine JJ, Dwyer JR, Chapman HD, Bell A, Robledo RF, Serreze DV. Direct-in-NOD genetic ablation of Bcl3 leads to complete type 1 diabetes protection. J Immunol. 2025 Nov 01; 214(11):2847-2860.

View in: PubMed
Serreze DV, Tousey-Pfarrer M, Racine JJ. Humanized Mouse Models for Type 1 Diabetes. Curr Protoc. 2025 Oct; 5(10):e70224.

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Megathlin HR, Burzenski L, Brehm MA, Greiner DL, Balu-Iyer S, Shultz LD. Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model. J Pharm Sci. 2025 Oct; 114(10):103964.

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Darguzyte M, Antczak P, Bachurski D, Hoelker P, Abedpour N, Gholamipoorfard R, Schl??er HA, Wennhold K, Thelen M, Garcia-Marquez MA, Koenig J, Schneider A, Braun T, Klawonn F, Damrat M, Rahman M, Kleid JM, Theobald SJ, Bauer E, von Kaisenberg C, Talbot SR, Shultz LD, Soper B, Stripecke R. Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles. Cells. 2024 10 12; 13(20).

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Serreze DV, Dwyer JR, Racine JJ. Advancing Animal Models of Human Type 1 Diabetes. Cold Spring Harb Perspect Med. 2024 Oct 01; 14(10).

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Lee J, Yurkovetskiy LA, Reiman D, Frommer L, Strong Z, Chang A, Kahaly GJ, Khan AA, Chervonsky AV. Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 09 03; 15(1):7688.

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Celhar T, Li X, Zhao Y, Tay HC, Lee A, Liew HH, Shepherdson EK, Rajarethinam R, Fan Y, Mak A, Chan JKY, Singhal A, Takahashi T. Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice. Stem Cell Res Ther. 2024 06 09; 15(1):164.

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Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.

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Racine JJ, Bachman JF, Zhang JG, Misherghi A, Khadour R, Kaisar S, Bedard O, Jenkins C, Abbott A, Forte E, Rainer P, Rosenthal N, Sattler S, Serreze DV. Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy. J Immunol. 2024 Apr 15; 212(8):1287-1306.

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