T-Lymphocytes

"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor ID	D013601
MeSH Number(s)	A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
Concept/Terms	T-Lymphocytes T-Lymphocytes T Lymphocytes T-Lymphocyte T-Cells T Cells T-Cell Thymus-Dependent Lymphocytes Lymphocyte, Thymus-Dependent Lymphocytes, Thymus-Dependent Thymus Dependent Lymphocytes Thymus-Dependent Lymphocyte

Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]

Below are MeSH descriptors whose meaning is related to "T-Lymphocytes".

Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.

Bar chart showing 612 publications over 31 distinct years, with a maximum of 31 publications in 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	11	8	19
1996	13	9	22
1997	12	4	16
1998	14	5	19
1999	17	14	31
2000	9	7	16
2001	11	11	22
2002	15	11	26
2003	10	13	23
2004	17	11	28
2005	15	9	24
2006	17	9	26
2007	12	13	25
2008	13	11	24
2009	13	5	18
2010	16	8	24
2011	8	8	16
2012	11	10	21
2013	12	8	20
2014	8	13	21
2015	8	9	17
2016	12	9	21
2017	10	5	15
2018	10	8	18
2019	6	10	16
2020	10	8	18
2021	7	11	18
2022	5	12	17
2023	1	8	9
2024	6	10	16
2025	3	3	6

Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.

Nanaware PP, Calvo-Calle JM, Redick SD, Tarpley MW, Cruz J, Clement CC, Manganaro A, Velarde de la Cruz EE, Muneeruddin K, Faulkner M, Wang JP, Shaffer SA, Harlan DM, Santambrogio L, Kent SC, Stern LJ. The antigen presentation landscape of cytokine-stressed human pancreatic islets. Cell Rep. 2025 Aug 26; 44(8):115927.

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Keeler AM, Zhan W, Ram S, Fitzgerald KA, Gao G. The curious case of AAV immunology. Mol Ther. 2025 May 07; 33(5):1946-1965.

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Gerber WK, Xie Y, Patel SA. Expanding the Therapeutic Reach of Chimeric Antigen Receptor T-Cells and Bispecific T-Cell Engagers Across Solid Tumors. JCO Precis Oncol. 2025 Mar; 9:e2400753.

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Kosti P, Abram-Saliba J, Pericou-Troquier L, Pavelot S, Ruggeri T, Laffaille M, Irving M, Coukos G, Lanitis E, Dunn SM. Potent and durable control of mesothelin-expressing tumors by a novel T cell-secreted bi-specific engager. J Immunother Cancer. 2025 Mar 13; 13(3).

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Elyaman W, Stern LJ, Jiang N, Dressman D, Bradley P, Klatzmann D, Bradshaw EM, Farber DL, Kent SC, Chizari S, Funk K, Devanand D, Thakur KT, Raj T, Dalahmah OA, Sarkis RA, Weiner HL, Shneider NA, Przedborski S. Exploring the role of T?cells in Alzheimer's and other neurodegenerative diseases: Emerging therapeutic insights from the T Cells in the Brain symposium. Alzheimers Dement. 2025 Feb; 21(2):e14548.

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Ezzedine K, Tannous R, Pearson TF, Harris JE. Recent clinical and mechanistic insights into vitiligo offer new treatment options for cell-specific autoimmunity. J Clin Invest. 2025 Jan 16; 135(2).

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Zhou L, Ma B, Ruscetti M. Cellular senescence offers distinct immunological vulnerabilities in cancer. Trends Cancer. 2025 Apr; 11(4):334-350.

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Darguzyte M, Antczak P, Bachurski D, Hoelker P, Abedpour N, Gholamipoorfard R, Schl??er HA, Wennhold K, Thelen M, Garcia-Marquez MA, Koenig J, Schneider A, Braun T, Klawonn F, Damrat M, Rahman M, Kleid JM, Theobald SJ, Bauer E, von Kaisenberg C, Talbot SR, Shultz LD, Soper B, Stripecke R. Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles. Cells. 2024 10 12; 13(20).

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Hojo-Souza NS, de Castro JT, Rivelli GG, Azevedo PO, Oliveira ER, Faustino LP, Salazar N, Bagno FF, Carvalho AF, Rattis B, Louren?o KL, Gomes IP, Assis BRD, Piccin M, Fonseca FG, Durigon E, Silva JS, de Souza RP, Goulart GAC, Santiago H, Fernandes APS, Teixeira SR, Gazzinelli RT. SpiN-Tec: A T cell-based recombinant vaccine that is safe, immunogenic, and shows high efficacy in experimental models challenged with SARS-CoV-2 variants of concern. Vaccine. 2024 12 02; 42(26):126394.

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Lee J, Yurkovetskiy LA, Reiman D, Frommer L, Strong Z, Chang A, Kahaly GJ, Khan AA, Chervonsky AV. Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 09 03; 15(1):7688.

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