T-Lymphocytes

"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor ID	D013601
MeSH Number(s)	A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
Concept/Terms	T-Lymphocytes T-Lymphocytes T Lymphocytes T-Lymphocyte T-Cells T Cells T-Cell Thymus-Dependent Lymphocytes Lymphocyte, Thymus-Dependent Lymphocytes, Thymus-Dependent Thymus Dependent Lymphocytes Thymus-Dependent Lymphocyte

Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]

Below are MeSH descriptors whose meaning is related to "T-Lymphocytes".

Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.

Bar chart showing 615 publications over 31 distinct years, with a maximum of 31 publications in 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	11	8	19
1996	13	9	22
1997	12	4	16
1998	14	5	19
1999	17	14	31
2000	9	7	16
2001	11	11	22
2002	15	11	26
2003	10	13	23
2004	17	11	28
2005	15	9	24
2006	17	9	26
2007	12	13	25
2008	13	11	24
2009	13	5	18
2010	16	8	24
2011	8	8	16
2012	11	10	21
2013	12	8	20
2014	8	13	21
2015	8	8	16
2016	12	9	21
2017	10	5	15
2018	10	8	18
2019	6	11	17
2020	10	8	18
2021	7	11	18
2022	5	12	17
2023	1	8	9
2024	6	10	16
2025	5	4	9

Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.

Almeida GG, Pinto JA, Pinto PM, da Silva LB, Andrade LAF, Valiate BVS, Zini N, Bagno FF, Rivelli GG, Louren?o KL, Souza JPC, Gomes IP, de Castro NS, Maia ALC, de Carvalho AF, Alves JC, de Castro JT, Li G, da Rocha Fernandes G, Alves PA, Diniz RC, Daher AB, de Souza RP, Teixeira SMR, Fernandes APSM, Gazzinelli RT, da Costa Santiago H. Safety and immunogenicity of SpiN-Tec, a T-cell based RBD-Nucleocapsid chimeric vaccine for COVID-19. Vaccine. 2025 Oct 03; 64:127756.

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Nanaware PP, Calvo-Calle JM, Redick SD, Tarpley MW, Cruz J, Clement CC, Manganaro A, Velarde de la Cruz EE, Muneeruddin K, Faulkner M, Wang JP, Shaffer SA, Harlan DM, Santambrogio L, Kent SC, Stern LJ. The antigen presentation landscape of cytokine-stressed human pancreatic islets. Cell Rep. 2025 Aug 26; 44(8):115927.

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Lefran?ais E, Hudrisier D, Neyrolles O, Behar SM, Ernst JD. Finding and filling the knowledge gaps in mechanisms of T cell-mediated TB immunity to inform vaccine design. Nat Rev Immunol. 2025 Nov; 25(11):798-815.

View in: PubMed
Keeler AM, Zhan W, Ram S, Fitzgerald KA, Gao G. The curious case of AAV immunology. Mol Ther. 2025 May 07; 33(5):1946-1965.

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Gerber WK, Xie Y, Patel SA. Expanding the Therapeutic Reach of Chimeric Antigen Receptor T-Cells and Bispecific T-Cell Engagers Across Solid Tumors. JCO Precis Oncol. 2025 Mar; 9:e2400753.

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Kosti P, Abram-Saliba J, Pericou-Troquier L, Pavelot S, Ruggeri T, Laffaille M, Irving M, Coukos G, Lanitis E, Dunn SM. Potent and durable control of mesothelin-expressing tumors by a novel T cell-secreted bi-specific engager. J Immunother Cancer. 2025 Mar 13; 13(3).

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Allard-Chamard H, Hillier K, Ramseier ML, Bertocchi A, Kaneko N, Premo K, Yuen G, Karpel M, Mahajan VS, Tsekeri C, Hong JS, Vencic J, Crotty R, Sharda AV, Barmettler S, Westermann-Clark E, Walter JE, Ghebremichael M, Shalek AK, Farmer JR, Pillai S. Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans. Blood Adv. 2025 Feb 11; 9(3):520-532.

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Elyaman W, Stern LJ, Jiang N, Dressman D, Bradley P, Klatzmann D, Bradshaw EM, Farber DL, Kent SC, Chizari S, Funk K, Devanand D, Thakur KT, Raj T, Dalahmah OA, Sarkis RA, Weiner HL, Shneider NA, Przedborski S. Exploring the role of T?cells in Alzheimer's and other neurodegenerative diseases: Emerging therapeutic insights from the T Cells in the Brain symposium. Alzheimers Dement. 2025 Feb; 21(2):e14548.

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Ezzedine K, Tannous R, Pearson TF, Harris JE. Recent clinical and mechanistic insights into vitiligo offer new treatment options for cell-specific autoimmunity. J Clin Invest. 2025 Jan 16; 135(2).

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Zhou L, Ma B, Ruscetti M. Cellular senescence offers distinct immunological vulnerabilities in cancer. Trends Cancer. 2025 Apr; 11(4):334-350.

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