Antigen Presentation

"Antigen Presentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process by which antigen is presented to lymphocytes in a form they can recognize. This is performed by antigen presenting cells (APCs). Some antigens require processing before they can be recognized. Antigen processing consists of ingestion and partial digestion of the antigen by the APC, followed by presentation of fragments on the cell surface. (From Rosen et al., Dictionary of Immunology, 1989)

Descriptor ID	D017951
MeSH Number(s)	G12.119 G12.450.050.400.070
Concept/Terms	Antigen Presentation Antigen Presentation Antigen Presentations Antigen Processing Antigen Processing Antigen Processings

Below are MeSH descriptors whose meaning is more general than "Antigen Presentation".

Biological Sciences [G]
Immune System Phenomena [G12]
Antigen Presentation [G12.119]
Immunity [G12.450]
Adaptive Immunity [G12.450.050]
Immunity, Cellular [G12.450.050.400]
Antigen Presentation [G12.450.050.400.070]

Below are MeSH descriptors whose meaning is related to "Antigen Presentation".

Below are MeSH descriptors whose meaning is more specific than "Antigen Presentation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen Presentation" by people in this website by year, and whether "Antigen Presentation" was a major or minor topic of these publications.

Bar chart showing 197 publications over 31 distinct years, with a maximum of 11 publications in 2005 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	7	3	10
1997	3	0	3
1998	5	4	9
1999	6	4	10
2000	6	2	8
2001	2	4	6
2002	7	3	10
2003	3	4	7
2004	3	7	10
2005	8	3	11
2006	8	2	10
2007	6	5	11
2008	4	4	8
2009	2	2	4
2010	4	5	9
2011	6	1	7
2012	3	3	6
2013	2	3	5
2014	3	3	6
2015	2	0	2
2016	3	4	7
2017	0	1	1
2018	3	4	7
2019	4	5	9
2020	2	0	2
2021	6	2	8
2022	1	0	1
2023	2	1	3
2024	0	1	1
2025	3	2	5
2026	1	0	1

Below are the most recent publications written about "Antigen Presentation" by people in Profiles.

Ramesh KM, Lu L, Stern LJ. T Cell Assay to Track Presentation of an Influenza Hemagglutinin Epitope Presented by the MHC-II Protein HLA-DR1. Methods Mol Biol. 2026; 3007:255-273.

View in: PubMed
Kane GI, Naylor TE, Lusi EF, Brassil ML, Wigglesworth K, Dinnell RW, Diaz-Infante MB, Whiteman LM, Lukas J, Winkler M, Josh R, Cerrutti J, Mori H, Gallucci S, Fitzgerald KA, Atukorale PU. Super-adjuvant nanoparticles for platform cancer vaccination. Cell Rep Med. 2025 Oct 21; 6(10):102415.

View in: PubMed
Nanaware PP, Calvo-Calle JM, Redick SD, Tarpley MW, Cruz J, Clement CC, Manganaro A, Velarde de la Cruz EE, Muneeruddin K, Faulkner M, Wang JP, Shaffer SA, Harlan DM, Santambrogio L, Kent SC, Stern LJ. The antigen presentation landscape of cytokine-stressed human pancreatic islets. Cell Rep. 2025 Aug 26; 44(8):115927.

View in: PubMed
Drake LA, Ramos RB, Denzin LK, Nanaware PP, Stern LJ, Drake JR. Conformational variants of I-Ak MHC class II molecules carry distinct immunopeptidomes. Mol Immunol. 2025 Mar; 179:128-140.

View in: PubMed
Carr? A, Samassa F, Zhou Z, Perez-Hernandez J, Lekka C, Manganaro A, Oshima M, Liao H, Parker R, Nicastri A, Brandao B, Colli ML, Eizirik DL, Aluri J, Patel D, G?ransson M, Burgos Morales O, Anderson A, Landry L, Kobaisi F, Scharfmann R, Marselli L, Marchetti P, You S, Nakayama M, Hadrup SR, Kent SC, Richardson SJ, Ternette N, Mallone R. Interferon-a promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic ?-cells. Nat Commun. 2025 Jan 17; 16(1):765.

View in: PubMed
Cruz FM, Orellano LAA, Chan A, Rock KL. Alternate MHC I Antigen Presentation Pathways Allow CD8+ T-cell Recognition and Killing of Cancer Cells in the Absence of ?2M or TAP. Cancer Immunol Res. 2025 Jan 09; 13(1):98-108.

View in: PubMed
Parsons BD, Medina-Luna D, Scur M, Pinelli M, Gamage GS, Chilvers RA, Hamon Y, Ahmed IHI, Savary S, Makrigiannis AP, Braverman NE, Rodriguez-Alcazar JF, Latz E, Karakach TK, Di Cara F. Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model. Cell Rep. 2024 02 27; 43(2):113744.

View in: PubMed
Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Molt? PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science. 2023 09 22; 381(6664):1316-1323.

View in: PubMed
Sari G, Rock KL. Tumor immune evasion through?loss of MHC class-I antigen presentation. Curr Opin Immunol. 2023 08; 83:102329.

View in: PubMed
Cruz FM, Chan A, Rock KL. Pathways of MHC I cross-presentation of exogenous antigens. Semin Immunol. 2023 03; 66:101729.

View in: PubMed

People

Explore

Similar Concepts

Top Journals