Heterotrimeric GTP-Binding Proteins

"Heterotrimeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.

Descriptor ID	D020962
MeSH Number(s)	D08.811.277.040.330.300.200 D12.644.360.360 D12.776.157.325.332 D12.776.476.375 D12.776.543.325
Concept/Terms	Heterotrimeric GTP-Binding Proteins Heterotrimeric GTP-Binding Proteins GTP-Binding Proteins, Heterotrimeric Heterotrimeric GTP Binding Proteins Heterotrimeric G-Proteins G-Proteins, Heterotrimeric Heterotrimeric G Proteins

Below are MeSH descriptors whose meaning is more general than "Heterotrimeric GTP-Binding Proteins".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Heterotrimeric GTP-Binding Proteins [D08.811.277.040.330.300.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Heterotrimeric GTP-Binding Proteins [D12.644.360.360]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Heterotrimeric GTP-Binding Proteins [D12.776.157.325.332]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Heterotrimeric GTP-Binding Proteins [D12.776.476.375]
Membrane Proteins [D12.776.543]
Heterotrimeric GTP-Binding Proteins [D12.776.543.325]

Below are MeSH descriptors whose meaning is related to "Heterotrimeric GTP-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "Heterotrimeric GTP-Binding Proteins".

Heterotrimeric GTP-Binding Proteins
GTP-Binding Protein alpha Subunits
Transducin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Heterotrimeric GTP-Binding Proteins" by people in this website by year, and whether "Heterotrimeric GTP-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1995 and 1996 and 1998 and 2002 and 2005 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1996	1	0	1
1998	1	0	1
2002	0	1	1
2005	1	0	1
2007	1	0	1

Below are the most recent publications written about "Heterotrimeric GTP-Binding Proteins" by people in Profiles.

Strickfaden SC, Pryciak PM. Distinct roles for two Galpha-Gbeta interfaces in cell polarity control by a yeast heterotrimeric G protein. Mol Biol Cell. 2008 Jan; 19(1):181-97.

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Winters MJ, Lamson RE, Nakanishi H, Neiman AM, Pryciak PM. A membrane binding domain in the ste5 scaffold synergizes with gbetagamma binding to control localization and signaling in pheromone response. Mol Cell. 2005 Oct 07; 20(1):21-32.

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Nishiguchi KM, Sandberg MA, Gorji N, Berson EL, Dryja TP. Cone cGMP-gated channel mutations and clinical findings in patients with achromatopsia, macular degeneration, and other hereditary cone diseases. Hum Mutat. 2005 Mar; 25(3):248-58.

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Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A. Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. Hum Mol Genet. 2004 Aug 01; 13(15):1563-75.

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Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res. 2002 Dec 15; 62(24):7203-6.

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Park JG, Bose A, Leszyk J, Czech MP. PYK2 as a mediator of endothelin-1/G alpha 11 signaling to GLUT4 glucose transporters. J Biol Chem. 2001 Dec 21; 276(51):47751-4.

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Dosil M, Schandel KA, Gupta E, Jenness DD, Konopka JB. The C terminus of the Saccharomyces cerevisiae alpha-factor receptor contributes to the formation of preactivation complexes with its cognate G protein. Mol Cell Biol. 2000 Jul; 20(14):5321-9.

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Butty AC, Pryciak PM, Huang LS, Herskowitz I, Peter M. The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science. 1998 Nov 20; 282(5393):1511-6.

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Pryciak PM, Hartwell LH. AKR1 encodes a candidate effector of the G beta gamma complex in the Saccharomyces cerevisiae pheromone response pathway and contributes to control of both cell shape and signal transduction. Mol Cell Biol. 1996 Jun; 16(6):2614-26.

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Dorer R, Pryciak PM, Hartwell LH. Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients. J Cell Biol. 1995 Nov; 131(4):845-61.

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