Autophagy-Related Protein-1 Homolog

"Autophagy-Related Protein-1 Homolog" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.

Descriptor ID	D000071189
MeSH Number(s)	D08.811.913.696.620.682.700.108 D12.644.360.081 D12.776.094.438 D12.776.476.078
Concept/Terms	Autophagy-Related Protein-1 Homolog Autophagy-Related Protein-1 Homolog Autophagy Related Protein 1 Homolog Serine-Threonine Protein Kinase ULK1 Serine Threonine Protein Kinase ULK1 Unc-51 Like Autophagy Activating Kinase 1 Unc 51 Like Autophagy Activating Kinase 1 ULK1 Protein Unc-51-Like Kinase 1 Unc 51 Like Kinase 1

Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein-1 Homolog".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Autophagy-Related Protein-1 Homolog [D08.811.913.696.620.682.700.108]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Autophagy-Related Protein-1 Homolog [D12.644.360.081]
Proteins [D12.776]
Autophagy-Related Proteins [D12.776.094]
Autophagy-Related Protein-1 Homolog [D12.776.094.438]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Autophagy-Related Protein-1 Homolog [D12.776.476.078]

Below are MeSH descriptors whose meaning is related to "Autophagy-Related Protein-1 Homolog".

Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein-1 Homolog".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Autophagy-Related Protein-1 Homolog" by people in this website by year, and whether "Autophagy-Related Protein-1 Homolog" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2010 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	0	1	1
2008	0	1	1
2010	0	2	2
2014	0	1	1
2016	1	0	1
2018	2	0	2

Below are the most recent publications written about "Autophagy-Related Protein-1 Homolog" by people in Profiles.

Nandy A, Lin L, Velentzas PD, Wu LP, Baehrecke EH, Silverman N. The NF-?B Factor Relish Regulates Atg1 Expression and Controls Autophagy. Cell Rep. 2018 11 20; 25(8):2110-2120.e3.

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Saleiro D, Blyth GT, Kosciuczuk EM, Ozark PA, Majchrzak-Kita B, Arslan AD, Fischietti M, Reddy NK, Horvath CM, Davis RJ, Fish EN, Platanias LC. IFN-?-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5. Sci Signal. 2018 11 20; 11(557).

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Li M, Lindblad JL, Perez E, Bergmann A, Fan Y. Autophagy-independent function of Atg1 for apoptosis-induced compensatory proliferation. BMC Biol. 2016 08 19; 14:70.

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P?rez E, Das G, Bergmann A, Baehrecke EH. Autophagy regulates tissue overgrowth in a context-dependent manner. Oncogene. 2015 Jun; 34(26):3369-76.

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Nezis IP, Shravage BV, Sagona AP, Lamark T, Bj?rk?y G, Johansen T, Rusten TE, Brech A, Baehrecke EH, Stenmark H. Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J Cell Biol. 2010 Aug 23; 190(4):523-31.

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McPhee CK, Logan MA, Freeman MR, Baehrecke EH. Activation of autophagy during cell death requires the engulfment receptor Draper. Nature. 2010 Jun 24; 465(7301):1093-6.

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Juh?sz G, Hill JH, Yan Y, Sass M, Baehrecke EH, Backer JM, Neufeld TP. The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. J Cell Biol. 2008 May 19; 181(4):655-66.

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Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell. 2007 Dec 14; 131(6):1137-48.

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