3-Phosphoinositide-Dependent Protein Kinases
"3-Phosphoinositide-Dependent Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3).
| Descriptor ID |
D064413
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| MeSH Number(s) |
D08.811.913.696.620.682.700.745
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| Concept/Terms |
3-Phosphoinositide-Dependent Protein Kinases- 3-Phosphoinositide-Dependent Protein Kinases
- 3 Phosphoinositide Dependent Protein Kinases
- Kinases, 3-Phosphoinositide-Dependent Protein
- Protein Kinases, 3-Phosphoinositide-Dependent
- 3-Phosphoinositide-Dependent Protein Kinase
- 3 Phosphoinositide Dependent Protein Kinase
- Kinase, 3-Phosphoinositide-Dependent Protein
- Protein Kinase, 3-Phosphoinositide-Dependent
3-Phosphoinositide Dependent Protein Kinase-1- 3-Phosphoinositide Dependent Protein Kinase-1
- 3 Phosphoinositide Dependent Protein Kinase 1
- 3-Phosphoinositide-Dependent Protein Kinase-1
- Kinase-1, 3-Phosphoinositide-Dependent Protein
- Protein Kinase-1, 3-Phosphoinositide-Dependent
- PtdIns(3,4,5)P3-Dependent Protein Kinase-1
- 3-Phosphoinositide-Dependent Kinase 1 (PDK1)
3-Phosphoinositide Dependent Protein Kinase-2- 3-Phosphoinositide Dependent Protein Kinase-2
- 3 Phosphoinositide Dependent Protein Kinase 2
- 3-Phosphoinositide-Dependent Protein Kinase-2
- Kinase-2, 3-Phosphoinositide-Dependent Protein
- Protein Kinase-2, 3-Phosphoinositide-Dependent
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Below are MeSH descriptors whose meaning is more general than "3-Phosphoinositide-Dependent Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "3-Phosphoinositide-Dependent Protein Kinases".
This graph shows the total number of publications written about "3-Phosphoinositide-Dependent Protein Kinases" by people in this website by year, and whether "3-Phosphoinositide-Dependent Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
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Below are the most recent publications written about "3-Phosphoinositide-Dependent Protein Kinases" by people in Profiles.
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Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S. PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science. 2005 Apr 01; 308(5718):114-8.
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Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science. 2005 Feb 18; 307(5712):1098-101.
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Steiler TL, Galuska D, Leng Y, Chibalin AV, Gilbert M, Zierath JR. Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. Endocrinology. 2003 Dec; 144(12):5259-67.
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Corvera S, Czech MP. Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction. Trends Cell Biol. 1998 Nov; 8(11):442-6.