Diabetes Mellitus, Type 2

"Diabetes Mellitus, Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Descriptor ID	D003924
MeSH Number(s)	C18.452.394.750.149 C19.246.300
Concept/Terms	Diabetes Mellitus, Type 2 Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Ketosis-Resistant Diabetes Mellitus, Ketosis Resistant Ketosis-Resistant Diabetes Mellitus Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus, Non-Insulin-Dependent Non-Insulin-Dependent Diabetes Mellitus Diabetes Mellitus, Stable Stable Diabetes Mellitus Diabetes Mellitus, Type II NIDDM Diabetes Mellitus, Noninsulin Dependent Diabetes Mellitus, Maturity-Onset Diabetes Mellitus, Maturity Onset Maturity-Onset Diabetes Mellitus Maturity Onset Diabetes Mellitus MODY Diabetes Mellitus, Slow-Onset Diabetes Mellitus, Slow Onset Slow-Onset Diabetes Mellitus Type 2 Diabetes Mellitus Noninsulin-Dependent Diabetes Mellitus Noninsulin Dependent Diabetes Mellitus Maturity-Onset Diabetes Diabetes, Maturity-Onset Maturity Onset Diabetes Type 2 Diabetes Diabetes, Type 2 Diabetes Mellitus, Adult-Onset Adult-Onset Diabetes Mellitus Diabetes Mellitus, Adult Onset

Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 2".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Glucose Metabolism Disorders [C18.452.394]
Diabetes Mellitus [C18.452.394.750]
Diabetes Mellitus, Type 2 [C18.452.394.750.149]
Endocrine System Diseases [C19]
Diabetes Mellitus [C19.246]
Diabetes Mellitus, Type 2 [C19.246.300]

Below are MeSH descriptors whose meaning is related to "Diabetes Mellitus, Type 2".

Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 2".

Diabetes Mellitus, Type 2
Diabetes Mellitus, Lipoatrophic

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Diabetes Mellitus, Type 2" by people in this website by year, and whether "Diabetes Mellitus, Type 2" was a major or minor topic of these publications.

Bar chart showing 469 publications over 30 distinct years, with a maximum of 35 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1996	0	1	1
1997	1	0	1
1998	2	0	2
1999	1	0	1
2000	0	1	1
2002	4	1	5
2003	5	0	5
2004	8	6	14
2005	10	2	12
2006	9	3	12
2007	9	4	13
2008	12	2	14
2009	13	11	24
2010	14	2	16
2011	20	6	26
2012	13	4	17
2013	23	6	29
2014	14	4	18
2015	28	6	34
2016	18	8	26
2017	20	5	25
2018	18	4	22
2019	19	5	24
2020	25	2	27
2021	21	2	23
2022	34	1	35
2023	22	0	22
2024	13	3	16
2025	3	0	3

Below are the most recent publications written about "Diabetes Mellitus, Type 2" by people in Profiles.

Colletta A, Cooper KM, Placentino G, Devuni D, Colletta C. Sodium-glucose cotransporter-2 inhibitor therapy improves renal and hepatic function in patients with cirrhosis secondary to metabolic dysfunction associated steatotic liver disease and type 2 diabetes. Front Endocrinol (Lausanne). 2025; 16:1531295.

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Goyal A, Saeed H, Sulaiman SA, Sultan W, Siddiqui MR, Kan Changez MI, Qamar A, Ganatra S, Dani SS. Emerging trends and disparities in cardiovascular, kidney, and diabetes-related mortality: A retrospective analysis of the wide-ranging online data for epidemiologic research database. PLoS One. 2025; 20(5):e0320670.

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Rizo-Roca D, Henderson JD, Zierath JR. Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes. J Intern Med. 2025 Jun; 297(6):584-607.

View in: PubMed
Sawalha K, Gautam N, Sivakumar K, Paydak H, Mehta JL. Metformin: Its salutary effects beyond diabetes mellitus. J Investig Med. 2025 Jun; 73(5):363-375.

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Bisht P, Bhattacharya A, Pal A, Singh R, Verma SK. Design and synthesis of novel 3,7-dihydro-1H-purine-2,6-diones as DPP-4 inhibitors: An in silico, in vitro and in vivo approach. Eur J Med Chem. 2025 Feb 05; 283:117160.

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Osataphan S, Awidi M, Jan YJ, Gunturu K, Sundararaman S, Viray H, Frankenberger E, Mariano M, O'Loughlin L, Piper-Vallillo A, Stafford K, Kolnick A, Ghazalah H, Sehgal K, Patti ME, Costa D, Lam P, Rangachari D. Association between higher glucose levels and reduced survival in patients with non-small cell lung cancer treated with immune checkpoint inhibitors. Lung Cancer. 2024 Dec; 198:108023.

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Doan TD, Suh L, Wu M, Cherng N, Perugini R. The role of socioeconomic status in resolution of type 2 diabetes mellitus following longitudinal sleeve gastrectomy. Surg Endosc. 2025 01; 39(1):568-576.

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Amante DJ, Shenette L, Wainaina S, Balakrishnan K, Bhatia S, Lee JA, Lemon SC, McManus D, Harlan DM, Malkani S, Gerber BS. Digital Health Tools and Behavioral Strategies to Increase Engagement With Diabetes Self-Management Education and Support: Design and Feasibility of DM-BOOST. Sci Diabetes Self Manag Care. 2024 Dec; 50(6):497-509.

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Rizo-Roca D, Guimar?es DSPSF, Pendergrast LA, Di Leo N, Chibalin AV, Maqdasy S, Ryd?n M, N?slund E, Zierath JR, Krook A. Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes. Sci Transl Med. 2024 Oct 09; 16(768):eado3022.

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Owolabi EO, Boakye MDS, Omololu SO, Smalls BL, Shaibi GQ. Technology-Based Interventions to Promote Diabetes Self-Management Behaviors for Persons Newly Diagnosed with Type 2 Diabetes: A Scoping Review. Curr Diab Rep. 2024 Dec; 24(12):257-272.

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