Diabetes Mellitus, Type 2

"Diabetes Mellitus, Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Descriptor ID	D003924
MeSH Number(s)	C18.452.394.750.149 C19.246.300
Concept/Terms	Diabetes Mellitus, Type 2 Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Ketosis-Resistant Diabetes Mellitus, Ketosis Resistant Ketosis-Resistant Diabetes Mellitus Diabetes Mellitus, Non Insulin Dependent Diabetes Mellitus, Non-Insulin-Dependent Non-Insulin-Dependent Diabetes Mellitus Diabetes Mellitus, Stable Stable Diabetes Mellitus Diabetes Mellitus, Type II NIDDM Diabetes Mellitus, Noninsulin Dependent Diabetes Mellitus, Maturity-Onset Diabetes Mellitus, Maturity Onset Maturity-Onset Diabetes Mellitus Maturity Onset Diabetes Mellitus MODY Diabetes Mellitus, Slow-Onset Diabetes Mellitus, Slow Onset Slow-Onset Diabetes Mellitus Type 2 Diabetes Mellitus Noninsulin-Dependent Diabetes Mellitus Noninsulin Dependent Diabetes Mellitus Maturity-Onset Diabetes Diabetes, Maturity-Onset Maturity Onset Diabetes Type 2 Diabetes Diabetes, Type 2 Diabetes Mellitus, Adult-Onset Adult-Onset Diabetes Mellitus Diabetes Mellitus, Adult Onset

Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 2".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Glucose Metabolism Disorders [C18.452.394]
Diabetes Mellitus [C18.452.394.750]
Diabetes Mellitus, Type 2 [C18.452.394.750.149]
Endocrine System Diseases [C19]
Diabetes Mellitus [C19.246]
Diabetes Mellitus, Type 2 [C19.246.300]

Below are MeSH descriptors whose meaning is related to "Diabetes Mellitus, Type 2".

Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 2".

Diabetes Mellitus, Type 2
Diabetes Mellitus, Lipoatrophic

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Diabetes Mellitus, Type 2" by people in this website by year, and whether "Diabetes Mellitus, Type 2" was a major or minor topic of these publications.

Bar chart showing 513 publications over 30 distinct years, with a maximum of 41 publications in 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1996	0	1	1
1997	1	0	1
1998	2	0	2
1999	1	0	1
2000	0	1	1
2002	4	1	5
2003	5	0	5
2004	8	6	14
2005	10	2	12
2006	9	2	11
2007	10	4	14
2008	13	2	15
2009	13	12	25
2010	15	2	17
2011	20	7	27
2012	14	4	18
2013	23	6	29
2014	16	4	20
2015	31	6	37
2016	20	8	28
2017	22	5	27
2018	19	5	24
2019	20	5	25
2020	28	3	31
2021	22	2	24
2022	40	1	41
2023	23	0	23
2024	19	4	23
2025	11	0	11

Below are the most recent publications written about "Diabetes Mellitus, Type 2" by people in Profiles.

Ramsey DJ, Makwana B, Dani SS, Patel M, Panchal K, Shah J, Khadke S, Kumar A, Patel T, Kosiborod MN, Fonarow GC, Ramsey KM, Nohria A, Butler J, Ganatra S. GLP-1 Receptor Agonists and Sight-Threatening Ophthalmic Complications in Patients With Type 2 Diabetes. JAMA Netw Open. 2025 Aug 01; 8(8):e2526321.

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Sen I, Smith JAB, Caria E, Orlov I, Savikj M, Brady AJ, Lian K, Ellefsen S, Zierath JR, Krook A. Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis. Sci Adv. 2025 Jul 11; 11(28):eads4371.

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Chung C, Lee KN, Han K, Park J, Shin DW, Lee SW. Physical activity intensity and amount are inversely correlated with the risk of tuberculosis in patients with diabetes. Sci Rep. 2025 Jul 09; 15(1):24701.

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Keller MJ, Brady AJ, Smith JAB, Savikj M, MacGregor K, Jollet M, ?berg SB, Nyl?n C, Bj?rnholm M, Rickenlund A, Carlsson M, Caidahl K, Krook A, Pillon NJ, Zierath JR, Wallberg-Henriksson H. Inflammatory markers and blood glucose are higher after morning vs afternoon exercise in type 2 diabetes. Diabetologia. 2025 Sep; 68(9):2023-2035.

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Makwana B, Khadke S, Kumar A, Nasir K, Wadhera R, Shah R, Sheth S, Kong Y, Navas-Acien A, Adamkiewicz G, Rajagopalan S, Al-Kindi S, Dani SS, Moffatt-Bruce S, Ganatra S. Marine Microplastic Levels and the Prevalence of Cardiometabolic Diseases in US Coastline Counties. J Am Heart Assoc. 2025 Jul; 14(13):e039891.

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Kj?rgaard J, Stocks B, Henderson J, Freemantle JB, Rizo-Roca D, Puglia M, Madrazo Montoya M, Andersson D, B?ckdahl J, Eriksson-Hogling D, Stidsen JV, Wierer M, Rasmussen S, Sakamoto K, H?jlund K, Ryd?n M, Zierath JR, Krook A, Deshmukh AS. Personalized molecular signatures of insulin resistance and type 2 diabetes. Cell. 2025 Jul 24; 188(15):4106-4122.e16.

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Colletta A, Cooper KM, Placentino G, Devuni D, Colletta C. Sodium-glucose cotransporter-2 inhibitor therapy improves renal and hepatic function in patients with cirrhosis secondary to metabolic dysfunction associated steatotic liver disease and type 2 diabetes. Front Endocrinol (Lausanne). 2025; 16:1531295.

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Goyal A, Saeed H, Sulaiman SA, Sultan W, Siddiqui MR, Kan Changez MI, Qamar A, Ganatra S, Dani SS. Emerging trends and disparities in cardiovascular, kidney, and diabetes-related mortality: A retrospective analysis of the wide-ranging online data for epidemiologic research database. PLoS One. 2025; 20(5):e0320670.

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Rizo-Roca D, Henderson JD, Zierath JR. Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes. J Intern Med. 2025 Jun; 297(6):584-607.

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Solomon M, Claudel S, Verma A. Cardiovascular-Kidney-Metabolic Health: Definition, Staging, Risk Assessment, and Therapeutic Considerations. Cardiol Clin. 2025 Aug; 43(3):337-357.

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