"Aurora Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell division, including centrosome duplication, SPINDLE APPARATUS formation, chromosome alignment, attachment to the spindle, checkpoint activation, and CYTOKINESIS.
Descriptor ID |
D064127
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MeSH Number(s) |
D08.811.913.696.620.682.700.103 D12.776.167.049
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aurora Kinases".
Below are MeSH descriptors whose meaning is more specific than "Aurora Kinases".
This graph shows the total number of publications written about "Aurora Kinases" by people in this website by year, and whether "Aurora Kinases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 2 | 2 |
2003 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2005 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aurora Kinases" by people in Profiles.
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Boeckmann L, Takahashi Y, Au WC, Mishra PK, Choy JS, Dawson AR, Szeto MY, Waybright TJ, Heger C, McAndrew C, Goldsmith PK, Veenstra TD, Baker RE, Basrai MA. Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae. Mol Biol Cell. 2013 Jun; 24(12):2034-44.
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Yoon Y, Cowley DO, Gallant J, Jones SN, Van Dyke T, Rivera-P?rez JA. Conditional Aurora A deficiency differentially affects early mouse embryo patterning. Dev Biol. 2012 Nov 01; 371(1):77-85.
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Chen CT, Hehnly H, Doxsey SJ. Orchestrating vesicle transport, ESCRTs and kinase surveillance during abscission. Nat Rev Mol Cell Biol. 2012 Jul 11; 13(8):483-8.
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Li Z, Rana TM. A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nat Commun. 2012; 3:1085.
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Hall LL, Byron M, Pageau G, Lawrence JB. AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome. J Cell Biol. 2009 Aug 24; 186(4):491-507.
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Chen CT, Doxsey S. A last-minute rescue of trapped chromatin. Cell. 2009 Feb 06; 136(3):397-9.
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Man C, Rosa J, Yip YL, Cheung AL, Kwong YL, Doxsey SJ, Tsao SW. Id1 overexpression induces tetraploidization and multiple abnormal mitotic phenotypes by modulating aurora A. Mol Biol Cell. 2008 Jun; 19(6):2389-401.
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Rosa J, Canovas P, Islam A, Altieri DC, Doxsey SJ. Survivin modulates microtubule dynamics and nucleation throughout the cell cycle. Mol Biol Cell. 2006 Mar; 17(3):1483-93.
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Cao Q, Huang YS, Kan MC, Richter JD. Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation. Mol Cell Biol. 2005 Dec; 25(24):10930-9.
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Trautmann S, Rajagopalan S, McCollum D. The S. pombe Cdc14-like phosphatase Clp1p regulates chromosome biorientation and interacts with Aurora kinase. Dev Cell. 2004 Nov; 7(5):755-62.