"Aurora Kinase A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION.
| Descriptor ID |
D064096
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.103.500 D12.776.167.049.500
|
| Concept/Terms |
Aurora Kinase A- Aurora Kinase A
- Aurora A Kinase
- Aurora A Kinases
- Aurora Kinases A
- STK15 Kinase
- AURORA2 Protein
- AuroraA Kinase
- Breast-Tumor-Amplified Kinase
- Breast Tumor Amplified Kinase
- BTAK Protein
- Serine-Threonine Protein Kinase 15
- Serine Threonine Protein Kinase 15
- AURKA
- Aurora-A Kinase
|
Below are MeSH descriptors whose meaning is more general than "Aurora Kinase A".
Below are MeSH descriptors whose meaning is more specific than "Aurora Kinase A".
This graph shows the total number of publications written about "Aurora Kinase A" by people in this website by year, and whether "Aurora Kinase A" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Aurora Kinase A" by people in Profiles.
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Chattopadhyay A, O'Connor CJ, Zhang F, Galvagnion C, Galloway WR, Tan YS, Stokes JE, Rahman T, Verma C, Spring DR, Itzhaki LS. Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell. Sci Rep. 2016 Apr 05; 6:23732.
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Massari F, Ciccarese C, Santoni M, Brunelli M, Conti A, Modena A, Montironi R, Santini D, Cheng L, Martignoni G, Cascinu S, Tortora G. The route to personalized medicine in bladder cancer: where do we stand? Target Oncol. 2015 Sep; 10(3):325-36.
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Yoon Y, Cowley DO, Gallant J, Jones SN, Van Dyke T, Rivera-P?rez JA. Conditional Aurora A deficiency differentially affects early mouse embryo patterning. Dev Biol. 2012 Nov 01; 371(1):77-85.
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Li Z, Rana TM. A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nat Commun. 2012; 3:1085.
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Cao Q, Huang YS, Kan MC, Richter JD. Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation. Mol Cell Biol. 2005 Dec; 25(24):10930-9.