Mitogen-Activated Protein Kinases

"Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).

Descriptor ID	D020928
MeSH Number(s)	D08.811.913.696.620.682.700.567 D12.644.360.450 D12.776.476.450
Concept/Terms	Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinases Kinases, Mitogen-Activated Protein Mitogen Activated Protein Kinases Protein Kinases, Mitogen-Activated

Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Mitogen-Activated Protein Kinases [D12.644.360.450]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Mitogen-Activated Protein Kinases [D12.776.476.450]

Below are MeSH descriptors whose meaning is related to "Mitogen-Activated Protein Kinases".

Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinases".

Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
JNK Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mitogen-Activated Protein Kinases" by people in this website by year, and whether "Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.

Bar chart showing 166 publications over 25 distinct years, with a maximum of 31 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	5	0	5
1999	6	0	6
2000	3	7	10
2001	4	8	12
2002	20	11	31
2003	16	10	26
2004	7	9	16
2005	2	2	4
2006	2	2	4
2007	4	3	7
2008	0	5	5
2009	1	0	1
2010	2	0	2
2011	1	1	2
2012	2	4	6
2013	0	5	5
2014	1	0	1
2015	2	3	5
2016	1	1	2
2017	0	1	1
2018	2	2	4
2019	2	3	5
2020	2	2	4
2021	0	1	1
2024	0	1	1

Below are the most recent publications written about "Mitogen-Activated Protein Kinases" by people in Profiles.

Gonzalez X, Irazoqui JE. Distinct members of the Caenorhabditis elegans CeMbio reference microbiota exert cryptic virulence that is masked by host defense. Mol Microbiol. 2024 09; 122(3):387-402.

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Kyriazis P, Tiwary A, Freeman J, Landry D, Braden G. Atypical anti-glomerular basement membrane glomerulonephritis in a patient with metastatic melanoma treated with mitogen-activated protein kinase and immune checkpoint inhibitors: a case report. J Med Case Rep. 2021 Apr 03; 15(1):186.

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Vasquez-Rifo A, Ricci EP, Ambros V. Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes. PLoS Biol. 2020 12; 18(12):e3000969.

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Janardhan HP, Meng X, Dresser K, Hutchinson L, Trivedi CM. KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K-MAPK1 inhibition. J Exp Med. 2020 07 06; 217(7).

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Leech CM, Flynn MJ, Arsenault HE, Ou J, Liu H, Zhu LJ, Benanti JA. The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network. PLoS Genet. 2020 04; 16(4):e1008600.

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Foster KJ, Cheesman HK, Liu P, Peterson ND, Anderson SM, Pukkila-Worley R. Innate Immunity in the C.?elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development. Cell Rep. 2020 04 07; 31(1):107478.

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Kumar NP, Moideen K, Nancy A, Viswanathan V, Shruthi BS, Sivakumar S, Hissar S, Kornfeld H, Babu S. Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy. BMC Infect Dis. 2019 Dec 09; 19(1):1039.

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Li H, Li Q, Dang K, Ma S, Cotton JL, Yang S, Zhu LJ, Deng AC, Ip YT, Johnson RL, Wu X, Punzo C, Mao J. YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression. Cell Rep. 2019 12 03; 29(10):3200-3211.e4.

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Rajaraman B, Ramadas N, Krishnasamy S, Ravi V, Pathak A, Devasena CS, Swaminathan K, Ganeshprasad A, Kuppuswamy AA, Vedantham S. Hyperglycaemia cause vascular inflammation through advanced glycation end products/early growth response-1 axis in gestational diabetes mellitus. Mol Cell Biochem. 2019 Jun; 456(1-2):179-190.

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Winters MJ, Pryciak PM. MAPK modulation of yeast pheromone signaling output and the role of phosphorylation sites in the scaffold protein Ste5. Mol Biol Cell. 2019 04 01; 30(8):1037-1049.

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