JNK Mitogen-Activated Protein Kinases
"JNK Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.
| Descriptor ID |
D048031
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.374 D12.644.360.450.340 D12.776.476.450.340
|
| Concept/Terms |
JNK Mitogen-Activated Protein Kinases- JNK Mitogen-Activated Protein Kinases
- JNK Mitogen Activated Protein Kinases
- jun-NH2-Terminal Kinase
- jun NH2 Terminal Kinase
- jun-NH2-Terminal Kinases
- jun NH2 Terminal Kinases
- c-jun Amino-Terminal Kinase
- Amino-Terminal Kinase, c-jun
- c jun Amino Terminal Kinase
- c-jun N-Terminal Kinase
- N-Terminal Kinase, c-jun
- c jun N Terminal Kinase
|
Below are MeSH descriptors whose meaning is more general than "JNK Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "JNK Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "JNK Mitogen-Activated Protein Kinases" by people in this website by year, and whether "JNK Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 1 | 2 | 3 |
| 2002 | 0 | 13 | 13 |
| 2003 | 2 | 9 | 11 |
| 2004 | 4 | 4 | 8 |
| 2005 | 1 | 3 | 4 |
| 2006 | 6 | 2 | 8 |
| 2007 | 3 | 4 | 7 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 3 | 4 |
| 2010 | 4 | 2 | 6 |
| 2011 | 4 | 0 | 4 |
| 2012 | 1 | 3 | 4 |
| 2013 | 2 | 2 | 4 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 3 | 3 |
| 2016 | 2 | 2 | 4 |
| 2017 | 2 | 3 | 5 |
| 2018 | 5 | 0 | 5 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2026 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "JNK Mitogen-Activated Protein Kinases" by people in Profiles.
-
Fern?ndez-Gonz?lez I, Vattathara JJ, Davis RJ, Sabio G, L?pez M. Attack of the kinases: JNK signaling in metabolism. Am J Physiol Regul Integr Comp Physiol. 2026 Apr 01; 330(4):R379-R395.
-
Farrell L, Puig-Barbe A, Haque MI, Amcheslavsky A, Yu M, Bergmann A, Fan Y. Actin remodeling mediates ROS production and JNK activation to drive apoptosis-induced proliferation. PLoS Genet. 2022 12; 18(12):e1010533.
-
Smith AO, Jonassen JA, Preval KM, Davis RJ, Pazour GJ. c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease. PLoS Genet. 2021 12; 17(12):e1009711.
-
Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ. JNK regulates muscle remodeling via myostatin/SMAD inhibition. Nat Commun. 2018 08 02; 9(1):3030.
-
Girnius N, Edwards YJ, Garlick DS, Davis RJ. The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation. Elife. 2018 06 01; 7.
-
West RJH, Ugbode C, Gao FB, Sweeney ST. The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia. Hum Mol Genet. 2018 04 15; 27(8):1382-1395.
-
Morel C, Sherrin T, Kennedy NJ, Forest KH, Avcioglu Barutcu S, Robles M, Carpenter-Hyland E, Alfulaij N, Standen CL, Nichols RA, Benveniste M, Davis RJ, Todorovic C. JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory. J Neurosci. 2018 04 11; 38(15):3708-3728.
-
Girnius N, Edwards YJK, Davis RJ. The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution. Cell Death Differ. 2018 09; 25(9):1702-1715.
-
Girnius N, Davis RJ. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017 Nov 14; 21(7):1910-1921.
-
Kant S, Standen CL, Morel C, Jung DY, Kim JK, Swat W, Flavell RA, Davis RJ. A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress. Cell Rep. 2017 Sep 19; 20(12):2775-2783.