Mitogen-Activated Protein Kinase 10
"Mitogen-Activated Protein Kinase 10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.
| Descriptor ID |
D048057
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.374.800 D12.644.360.450.340.800 D12.776.476.450.340.800
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 10- Mitogen-Activated Protein Kinase 10
- Mitogen Activated Protein Kinase 10
- c-jun Kinase 3
- Kinase 3, c-jun
- c jun Kinase 3
- Mitogen Activated Protein Kinase p49(3F12)
- p49 3F12 Kinase
- 3F12 Kinase, p49
- p49(3F12) SAP Kinase
- MAPK10 Mitogen-Activated Protein Kinase
- MAPK10 Mitogen Activated Protein Kinase
- Stress-Activated Protein Kinase JNK3
- Stress Activated Protein Kinase JNK3
- c-jun N-Terminal Kinase 3
- c jun N Terminal Kinase 3
- JNK3 Mitogen Activated Protein Kinase
- MAP Kinase p49(3F12)
- p54-SAPK(beta)
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 10".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 10".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 10" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 10" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 10" by people in Profiles.
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Kant S, Craige SM, Chen K, Reif MM, Learnard H, Kelly M, Caliz AD, Tran KV, Ramo K, Peters OM, Freeman M, Davis RJ, Keaney JF. Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis. Nat Commun. 2019 09 17; 10(1):4223.
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Vernia S, Morel C, Madara JC, Cavanagh-Kyros J, Barrett T, Chase K, Kennedy NJ, Jung DY, Kim JK, Aronin N, Flavell RA, Lowell BB, Davis RJ. Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress. Elife. 2016 Feb 24; 5:e10031.
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Sherrin T, Blank T, Hippel C, Rayner M, Davis RJ, Todorovic C. Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning. J Neurosci. 2010 Oct 06; 30(40):13348-61.
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Barnat M, Enslen H, Propst F, Davis RJ, Soares S, Nothias F. Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration. J Neurosci. 2010 Jun 09; 30(23):7804-16.
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Tachibana H, Perrino C, Takaoka H, Davis RJ, Naga Prasad SV, Rockman HA. JNK1 is required to preserve cardiac function in the early response to pressure overload. Biochem Biophys Res Commun. 2006 May 19; 343(4):1060-6.
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Keramaris E, Vanderluit JL, Bahadori M, Mousavi K, Davis RJ, Flavell R, Slack RS, Park DS. c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation. J Biol Chem. 2005 Jan 14; 280(2):1132-41.
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Kuan CY, Whitmarsh AJ, Yang DD, Liao G, Schloemer AJ, Dong C, Bao J, Banasiak KJ, Haddad GG, Flavell RA, Davis RJ, Rakic P. A critical role of neural-specific JNK3 for ischemic apoptosis. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15184-9.
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Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell. 2000 Oct 13; 103(2):239-52.