Below are the most recent publications written about "Hepatocytes" by people in Profiles.
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Ravi S, Sharma T, Yip M, Yang H, Xie J, Gao G, Tai PWL. A deep learning model trained on expressed transcripts across different tissue types reveals cell-type codon-optimization preferences. Nucleic Acids Res. 2025 Mar 20; 53(6).
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Varanasi SK, Chen D, Liu Y, Johnson MA, Miller CM, Ganguly S, Lande K, LaPorta MA, Hoffmann FA, Mann TH, Teneche MG, Casillas E, Mangalhara KC, Mathew V, Sun M, Jensen IJ, Farsakoglu Y, Chen T, Parisi B, Deota S, Havas A, Lee J, Chung HK, Schietinger A, Panda S, Williams AE, Farber DL, Dhar D, Adams PD, Feng GS, Shadel GS, Sundrud MS, Kaech SM. Bile acid synthesis impedes tumor-specific T cell responses during liver cancer. Science. 2025 Jan 10; 387(6730):192-201.
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Watson BR, Paul B, Rahman RU, Amir-Zilberstein L, Segerstolpe ?, Epstein ET, Murphy S, Geistlinger L, Lee T, Shih A, Deguine J, Xavier RJ, Moffitt JR, Mullen AC. Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution. Nat Commun. 2025 Jan 02; 16(1):319.
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Ortega-Ribera M, Zhuang Y, Babuta M, Brezani V, Joshi RS, Zsengeller Z, Thevkar Nagesh P, Wang Y, Bronson R, Szabo G. A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition. Cell Mol Gastroenterol Hepatol. 2025; 19(4):101446.
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Babuta M, Nagesh PT, Datta AA, Remotti V, Zhuang Y, Mehta J, Lami F, Wang Y, Szabo G. Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1? Axis in the Liver. Cells. 2024 06 01; 13(11).
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Gruntman AM, Xue W, Flotte TR. Alpha-1 Antitrypsin Deficiency. Methods Mol Biol. 2024; 2750:1-7.
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Guay KP, Ke H, Gierasch LM, Gershenson A, Hebert DN. Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types. Methods Mol Biol. 2024; 2750:143-163.
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Ohkubo R, Mu WC, Wang CL, Song Z, Barthez M, Wang Y, Mitchener N, Abdullayev R, Lee YR, Ma Y, Curtin M, Srinivasan S, Zhang X, Yang F, Sudmant PH, Pisco AO, Neff N, Haynes CM, Chen D. The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease. Cell Rep. 2022 12 13; 41(11):111803.
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Vernia S, Lee A, Kennedy NJ, Han MS, Isasa M, Cavanagh-Kyros J, Roy A, Syed A, Chaudhry S, Edwards YJK, Gygi SP, Gao G, Davis RJ. Phosphorylation of RXRa mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2210434119.
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Cho Y, Joshi R, Lowe P, Copeland C, Ribeiro M, Morel C, Catalano D, Szabo G. Granulocyte colony-stimulating factor attenuates liver damage by M2 macrophage polarization and hepatocyte proliferation in alcoholic hepatitis in mice. Hepatol Commun. 2022 09; 6(9):2322-2339.