Keratinocytes

"Keratinocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

Descriptor ID	D015603
MeSH Number(s)	A11.436.397
Concept/Terms	Keratinocytes Keratinocytes Keratinocyte

Below are MeSH descriptors whose meaning is more general than "Keratinocytes".

Anatomy [A]
Cells [A11]
Epithelial Cells [A11.436]
Keratinocytes [A11.436.397]

Below are MeSH descriptors whose meaning is more specific than "Keratinocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Keratinocytes" by people in this website by year, and whether "Keratinocytes" was a major or minor topic of these publications.

Bar chart showing 50 publications over 24 distinct years, with a maximum of 4 publications in 2006 and 2011 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	1	1	2
2000	1	0	1
2003	0	1	1
2004	0	1	1
2005	1	1	2
2006	0	4	4
2007	1	0	1
2008	2	1	3
2009	1	1	2
2010	0	1	1
2011	2	2	4
2012	1	0	1
2013	2	0	2
2014	1	2	3
2015	2	2	4
2016	0	3	3
2017	1	1	2
2018	0	1	1
2019	0	2	2
2020	1	2	3
2022	0	1	1
2023	1	2	3
2024	0	2	2

Below are the most recent publications written about "Keratinocytes" by people in Profiles.

Hamzavi IH, Ganesan AK, Mahmoud BH, Weiss E, Ahmed AM, Robinson D, Goldman MP, Munavalli G, Kahn SA, Huang V, Waibel J, Desai A, Elbuluk N, Desai S, Pandya AG. Effective and durable repigmentation for stable vitiligo: A randomized within-subject controlled trial assessing treatment with autologous skin cell suspension transplantation. J Am Acad Dermatol. 2024 Dec; 91(6):1104-1112.

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Parameswaran P, Payne L, Powers J, Rashighi M, Orzalli MH. A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome. J Exp Med. 2024 Aug 05; 221(8).

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Ceol CJ. Microenvironmental GABA Signaling Regulates Melanomagenesis through Reciprocal Melanoma-Keratinocyte Communication. Cancer Discov. 2023 10 05; 13(10):2128-2130.

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Refat MA, Strassner JP, Frisoli ML, Rashighi M, Richmond J, Nada E, Saleh R, El-Hamd MA, Goldberg D, Mahmoud BH, Harris JE. Lesional CD8+ T-Cell Number Predicts Surgical Outcomes of Melanocyte-Keratinocyte Transplantation Surgery for Vitiligo. J Invest Dermatol. 2023 11; 143(11):2275-2282.e6.

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Zhou JY, Sarkar MK, Okamura K, Harris JE, Gudjonsson JE, Fitzgerald KA. Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT). Proc Natl Acad Sci U S A. 2023 01 31; 120(5):e2213777120.

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Hsueh YC, Wang Y, Riding RL, Catalano DE, Lu YJ, Richmond JM, Siegel DL, Rusckowski M, Stanley JR, Harris JE. A Keratinocyte-Tethered Biologic Enables Location-Precise Treatment in Mouse Vitiligo. J Invest Dermatol. 2022 12; 142(12):3294-3303.

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Liu S, de Medeiros MC, Fernandez EM, Zarins KR, Cavalcante RG, Qin T, Wolf GT, Figueroa ME, D'Silva NJ, Rozek LS, Sartor MA. 5-Hydroxymethylation highlights the heterogeneity in keratinization and cell junctions in head and neck cancers. Clin Epigenetics. 2020 11 17; 12(1):175.

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Spidale NA, Malhotra N, Frascoli M, Sylvia K, Miu B, Freeman C, Stadinski BD, Huseby E, Kang J. Neonatal-derived IL-17 producing dermal ?d T cells are required to prevent spontaneous atopic dermatitis. Elife. 2020 02 17; 9.

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Szymczak K, Pelletier MGH, Gaines PCW. Quantification of Chemotaxis or Respiratory Burst Using Ex Vivo Culture-Derived Murine Neutrophils. Methods Mol Biol. 2020; 2087:93-106.

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Cau L, Takahara H, Thompson PR, Serre G, M?chin MC, Simon M. Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in?Reconstructed Human Epidermis. J Invest Dermatol. 2019 09; 139(9):1889-1897.e4.

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