Keratinocytes

"Keratinocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

Descriptor ID	D015603
MeSH Number(s)	A11.436.397
Concept/Terms	Keratinocytes Keratinocytes Keratinocyte

Below are MeSH descriptors whose meaning is more general than "Keratinocytes".

Anatomy [A]
Cells [A11]
Epithelial Cells [A11.436]
Keratinocytes [A11.436.397]

Below are MeSH descriptors whose meaning is more specific than "Keratinocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Keratinocytes" by people in this website by year, and whether "Keratinocytes" was a major or minor topic of these publications.

Bar chart showing 57 publications over 25 distinct years, with a maximum of 5 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	1	1	2
2000	1	0	1
2003	0	2	2
2004	0	1	1
2005	1	1	2
2006	0	4	4
2007	1	0	1
2008	2	1	3
2009	1	1	2
2010	0	1	1
2011	2	2	4
2012	1	0	1
2013	2	1	3
2014	3	2	5
2015	2	2	4
2016	0	3	3
2017	1	1	2
2018	0	1	1
2019	0	2	2
2020	1	2	3
2022	0	2	2
2023	1	3	4
2024	0	2	2
2026	1	0	1

Below are the most recent publications written about "Keratinocytes" by people in Profiles.

Wang Y, Afshari K, Haddadi NS, Lopes CS, Eng CL, Whiteman LM, Martinez N, Kyawe PP, Anufrieva KS, Wei K, Frieda K, Rosenbach M, Vleugels RA, Gallucci S, Harris JE, Rashighi M, Garber M. A spatially coordinated keratinocyte-fibroblast circuit recruits MMP9+ myeloid cells to drive type I interferon-driven inflammation in photosensitive autoimmunity. Nat Immunol. 2026 Jun; 27(6):1184-1196.

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Hamzavi IH, Ganesan AK, Mahmoud BH, Weiss E, Ahmed AM, Robinson D, Goldman MP, Munavalli G, Kahn SA, Huang V, Waibel J, Desai A, Elbuluk N, Desai S, Pandya AG. Effective and durable repigmentation for stable vitiligo: A randomized within-subject controlled trial assessing treatment with autologous skin cell suspension transplantation. J Am Acad Dermatol. 2024 12; 91(6):1104-1112.

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Parameswaran P, Payne L, Powers J, Rashighi M, Orzalli MH. A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome. J Exp Med. 2024 Aug 05; 221(8).

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Lin X, Chu J, Xiang Y, He M, Ma Q, Duan J, Wang Y, Sun S. Kangfuxin liquid reduces the ultraviolet B-induced photodamage of HaCaT cells by regulating autophagy. Biosci Biotechnol Biochem. 2023 Nov 21; 87(12):1485-1494.

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Ceol CJ. Microenvironmental GABA Signaling Regulates Melanomagenesis through Reciprocal Melanoma-Keratinocyte Communication. Cancer Discov. 2023 10 05; 13(10):2128-2130.

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Refat MA, Strassner JP, Frisoli ML, Rashighi M, Richmond J, Nada E, Saleh R, El-Hamd MA, Goldberg D, Mahmoud BH, Harris JE. Lesional CD8+ T-Cell Number Predicts Surgical Outcomes of Melanocyte-Keratinocyte Transplantation Surgery for Vitiligo. J Invest Dermatol. 2023 11; 143(11):2275-2282.e6.

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Zhou JY, Sarkar MK, Okamura K, Harris JE, Gudjonsson JE, Fitzgerald KA. Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT). Proc Natl Acad Sci U S A. 2023 01 31; 120(5):e2213777120.

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Jin J, Zhu KS, Tang SM, Xiang Y, Mao MY, Hong XD, Chen AF, Zhang XD, Lu H, Chen ZL, Wu JF, Pan SF, Zhu SH. Trehalose promotes functional recovery of keratinocytes under oxidative stress and wound healing via ATG5/ATG7. Burns. 2023 09; 49(6):1382-1391.

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Hsueh YC, Wang Y, Riding RL, Catalano DE, Lu YJ, Richmond JM, Siegel DL, Rusckowski M, Stanley JR, Harris JE. A Keratinocyte-Tethered Biologic Enables Location-Precise Treatment in Mouse Vitiligo. J Invest Dermatol. 2022 12; 142(12):3294-3303.

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Liu S, de Medeiros MC, Fernandez EM, Zarins KR, Cavalcante RG, Qin T, Wolf GT, Figueroa ME, D'Silva NJ, Rozek LS, Sartor MA. 5-Hydroxymethylation highlights the heterogeneity in keratinization and cell junctions in head and neck cancers. Clin Epigenetics. 2020 11 17; 12(1):175.

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