HEK293 Cells

"HEK293 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cell line generated from human embryonic kidney cells that were transformed with human adenovirus type 5.

Descriptor ID	D057809
MeSH Number(s)	A11.251.210.172.750 A11.436.334
Concept/Terms	HEK293 Cells HEK293 Cells Cell, HEK293 Cells, HEK293 HEK293 Cell 293T Cells 293T Cell Cell, 293T Cells, 293T HEK 293 Cells 293 Cell, HEK 293 Cells, HEK Cell, HEK 293 Cells, HEK 293 HEK 293 Cell Human Kidney Cell Line 293 Human Embryonic Kidney Cell Line 293 HEK 293 Cell Line

Below are MeSH descriptors whose meaning is more general than "HEK293 Cells".

Anatomy [A]
Cells [A11]
Cells, Cultured [A11.251]
Cell Line [A11.251.210]
Cell Line, Transformed [A11.251.210.172]
HEK293 Cells [A11.251.210.172.750]
Epithelial Cells [A11.436]
HEK293 Cells [A11.436.334]

Below are MeSH descriptors whose meaning is more specific than "HEK293 Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "HEK293 Cells" by people in this website by year, and whether "HEK293 Cells" was a major or minor topic of these publications.

Bar chart showing 433 publications over 16 distinct years, with a maximum of 55 publications in 2018

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2010	6	6
2011	33	33
2012	30	30
2013	44	44
2014	36	36
2015	24	24
2016	25	25
2017	32	32
2018	55	55
2019	51	51
2020	35	35
2021	32	32
2022	9	9
2023	3	3
2024	12	12
2025	6	6

Below are the most recent publications written about "HEK293 Cells" by people in Profiles.

Ahmed M, Fischer S, Robert KL, Lange KI, Stuck MW, Best S, Johnson CA, Pazour GJ, Blacque OE, Nandadasa S. Cleavage of the Meckel-Gruber syndrome protein TMEM67 by ADAMTS9 uncouples Wnt signaling and ciliogenesis. Nat Commun. 2025 May 28; 16(1):4946.

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Liu H, Liu N, Zhou C, Du A, Kapadia M, Tai PWL, Barton E, Gao G, Wang D. High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling. EMBO Mol Med. 2025 Jun; 17(6):1475-1494.

View in: PubMed
Olety B, Usami Y, Peters P, Wu Y, G?ttlinger H. The ectodomain sheddase ADAM10 restricts HIV-1 propagation and is counteracted by Nef. Sci Adv. 2025 Apr 18; 11(16):eadt1836.

View in: PubMed
Green EA, Fu Q, Ndahiro N, Leibiger TM, Wang Y, Lee Y, Lee KH, Betenbaugh M, Yoon S, McNally DJ. Development of an HEK293 Suspension Cell Culture Medium, Transient Transfection Optimization Workflow, and Analytics for Batch rAAV Manufacturing. Biotechnol Bioeng. 2025 Jul; 122(7):1640-1655.

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Wang Y, Fu Q, Sha S, Yoon S. Interferon inhibitors increase rAAV production in HEK293 cells. J Biotechnol. 2025 Mar; 399:9-18.

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Lee JM, Zeng J, Liu P, Nguyen MA, Suchenski Loustaunau D, Bauer DE, Kurt Yilmaz N, Wolfe SA, Schiffer CA. Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets. Nucleic Acids Res. 2025 Jan 07; 53(1).

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Padron A, Dwivedi R, Chakraborty R, Prakash P, Kim K, Shi J, Ahn J, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C. Cyclophilin A facilitates HIV-1 integration. J Virol. 2024 Nov 19; 98(11):e0094724.

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Greiner-Tollersrud OK, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, Abdullah Z, Andryka-Cegielski K, Dominick FI, Huebscher K, Goschin A, Smulski CR, Trompouki E, Link R, Ebersbach H, Srinivas H, Marchant M, Sogkas G, Staab D, V?gb? C, Guerini D, Baasch S, Latz E, Hartmann G, Henneke P, Geiger R, Peng XP, Grimbacher B, Bartok E, Alseth I, Warncke M, Proietti M. ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA. Cell Rep. 2024 11 26; 43(11):114899.

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MalagodaPathiranage K, Banerjee R, Martin CT. A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase. Nucleic Acids Res. 2024 Sep 23; 52(17):10607-10618.

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Jo M, Lee JS, Tocheny CE, Lero MW, Bui QT, Morgan JS, Shaw LM. Fluorescent tagging of endogenous IRS2 with an auxin-dependent degron to assess dynamic intracellular localization and function. J Biol Chem. 2024 11; 300(11):107796.

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