"Myotonin-Protein Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.
| Descriptor ID |
D065636
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.576
|
| Concept/Terms |
Myotonin-Protein Kinase- Myotonin-Protein Kinase
- Kinase, Myotonin-Protein
- Myotonin Protein Kinase
- DM-Kinase
- DM Kinase
- Myotonic Dystrophy Protein Kinase
- DMPK Protein
- Protein, DMPK
- MDGP Protein
- Protein, MDGP
- MDPK Protein
- Protein, MDPK
- DM Protein Kinase
- Kinase, DM Protein
- Protein Kinase, DM
- DM1PK Protein
- Protein, DM1PK
|
Below are MeSH descriptors whose meaning is more general than "Myotonin-Protein Kinase".
Below are MeSH descriptors whose meaning is more specific than "Myotonin-Protein Kinase".
This graph shows the total number of publications written about "Myotonin-Protein Kinase" by people in this website by year, and whether "Myotonin-Protein Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myotonin-Protein Kinase" by people in Profiles.
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Smith KP, Byron M, Johnson C, Xing Y, Lawrence JB. Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains. J Cell Biol. 2007 Sep 10; 178(6):951-64.
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Lieberman SM, Takaki T, Han B, Santamaria P, Serreze DV, DiLorenzo TP. Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase. J Immunol. 2004 Dec 01; 173(11):6727-34.