RNA, Long Noncoding

"RNA, Long Noncoding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.

Descriptor ID	D062085
MeSH Number(s)	D13.444.735.790.375
Concept/Terms	RNA, Long Noncoding RNA, Long Noncoding Noncoding RNA, Long lncRNA Long ncRNA ncRNA, Long RNA, Long Non-Translated Long Non-Translated RNA Non-Translated RNA, Long RNA, Long Non Translated Long Non-Coding RNA Long Non Coding RNA Non-Coding RNA, Long RNA, Long Non-Coding Long Non-Protein-Coding RNA Long Non Protein Coding RNA Non-Protein-Coding RNA, Long RNA, Long Non-Protein-Coding Long Noncoding RNA RNA, Long Untranslated Long Untranslated RNA Untranslated RNA, Long Long ncRNAs ncRNAs, Long Long Intergenic Non-Protein Coding RNA Long Intergenic Non-Protein Coding RNA Long Intergenic Non Protein Coding RNA LincRNAs LINC RNA

Below are MeSH descriptors whose meaning is more general than "RNA, Long Noncoding".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Untranslated [D13.444.735.790]
RNA, Long Noncoding [D13.444.735.790.375]

Below are MeSH descriptors whose meaning is related to "RNA, Long Noncoding".

Below are MeSH descriptors whose meaning is more specific than "RNA, Long Noncoding".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA, Long Noncoding" by people in this website by year, and whether "RNA, Long Noncoding" was a major or minor topic of these publications.

Bar chart showing 115 publications over 24 distinct years, with a maximum of 12 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	4	4
2003	0	2	2
2004	0	1	1
2005	0	1	1
2006	0	1	1
2007	0	3	3
2008	0	1	1
2009	0	1	1
2010	0	1	1
2011	0	2	2
2012	1	1	2
2013	6	0	6
2014	7	3	10
2015	6	1	7
2016	7	4	11
2017	7	1	8
2018	6	3	9
2019	3	1	4
2020	8	1	9
2021	1	1	2
2022	4	0	4
2023	7	0	7
2024	11	1	12
2025	4	3	7

Below are the most recent publications written about "RNA, Long Noncoding" by people in Profiles.

Rahman RU, Ahmad I, Li Z, Sparks RP, Ben Saad A, Mullen AC. Singletrome enhances detection of long noncoding RNAs in single cell transcriptomes. Sci Rep. 2025 Aug 12; 15(1):29542.

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Sen I, Smith JAB, Caria E, Orlov I, Savikj M, Brady AJ, Lian K, Ellefsen S, Zierath JR, Krook A. Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis. Sci Adv. 2025 Jul 11; 11(28):eads4371.

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Salsi V, Losi F, Fosso B, Ferrarini M, Pini S, Manfredi M, Vattemi G, Mongini T, Maggi L, Pesole G, Henras AK, Kaufman PD, McStay B, Tupler R. Nucleolar FRG2 lncRNAs inhibit rRNA transcription and cytoplasmic translation, linking FSHD to dysregulation of muscle-specific protein synthesis. Nucleic Acids Res. 2025 Jul 08; 53(13).

View in: PubMed
Lou S, DJiake Tihagam R, Wasko UN, Equbal Z, Venkatesan S, Braczyk K, Przanowski P, Il Koo B, Saltani I, Singh AT, Likhite S, Powers S, Souza GMPR, Maxwell RA, Yu J, Zhu LJ, Beenhakker M, Abbott SBG, Lu Z, Green MR, Meyer KC, Tushir-Singh J, Bhatnagar S. Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype. Nat Commun. 2025 Jul 04; 16(1):6169.

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Ling X, Golovenko D, Gan J, Ma J, Korostelev AA, Fang W. Cryo-EM structure of a natural RNA nanocage. Nature. 2025 Aug; 644(8078):1107-1115.

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Kant S, Caliz AD, Yoo HJ, Kaur G, Learnard H, Khalil HA, Davis RJ, Keaney JFJ. Mixed lineage kinase (MLK) controls tumor development and angiogenesis. Angiogenesis. 2025 May 02; 28(3):29.

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Fritz A, Pacht E, Toor R, Warren J, Greenyer H, Del Porto J, Person A, Korzec S, Zotkin G, Heath J, Ghule P, Gordon J, Van Wijnen A, Frietze S, Glass K, Lian J, Stein J, Stein GS. Mitotic bookmarking provides epigenetic persistence or plasticity for biological control and cancer. Biochem Cell Biol. 2025 Jan 01; 103:1-10.

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Bighetti-Trevisan RL, Almeida LO, Ramos JIR, Freitas GP, Oliveira FS, Gordon JAR, Tye CE, Stein GS, Lian JB, Stein JL, Rosa AL, Beloti MM. The effect of osteoclasts on epigenetic regulation by long non-coding RNAs in osteoblasts grown on titanium with nanotopography. Biomater Adv. 2025 Mar; 168:214128.

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Rahman S, Bloye G, Farah N, Demeulemeester J, Costa JR, O'Connor D, Pocock R, Rapoz-D'Silva T, Turna A, Wang L, Lee S, Fielding AK, Roels J, Jaksik R, Dawidowska M, Van Vlierberghe P, Hadjur S, Hughes JR, Davies JOJ, Gutierrez A, Kelliher MA, Van Loo P, Dawson MA, Mansour MR. Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia. Blood. 2024 Nov 28; 144(22):2319-2326.

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Shahzad U, Nikolopoulos M, Li C, Johnston M, Wang JJ, Sabha N, Varn FS, Riemenschneider A, Krumholtz S, Krishnamurthy PM, Smith CA, Karamchandani J, Watts JK, Verhaak RGW, Gallo M, Rutka JT, Das S. CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma. Mol Oncol. 2025 Mar; 19(3):764-784.

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